Use of Behavioral Economics in Repeat SARS-CoV-2 (COVID-19) Antibody Testing in Disadvantaged Communities

Sponsor
University of Southern California (Other)
Overall Status
Enrolling by invitation
CT.gov ID
NCT04901624
Collaborator
AltaMed Health Services (Other), National Institute on Aging (NIA) (NIH)
2,160
1
4
20
107.8

Study Details

Study Description

Brief Summary

Repeat testing for SARS-CoV-2 antibodies in disadvantaged communities will help identify active and recovered infections over time, and as more is understood about antibody protection, it may help identify persons who have immunity. Many questions about social barriers and behavioral facilitators remain unanswered. This project aims to evaluate the effectiveness of risk-based messaging and incentives that promote repeated testing for SARS-CoV-2 antibodies, as well as to understand social and behavioral determinants of COVID-19 testing and variations within sub-groups of this population.

Condition or Disease Intervention/Treatment Phase
  • Behavioral: Family Risk Messaging
  • Behavioral: Personal Risk Messaging
  • Behavioral: Loss Protection
  • Behavioral: Lottery Incentive
N/A

Detailed Description

The rapid spread of the SARS-CoV-2 virus has greatly impacted underserved populations. This project aims to understand social and behavioral determinants of COVID-19 testing and variations within sub-groups of this population. In partnership with the largest federally qualified health center in the United States, investigators will collect survey data and conduct a randomized experiment on 2,160 individuals (540 families) to evaluate the effectiveness of risk-based messaging and incentives that promote repeated testing for SARS-CoV-2 antibodies. In a 2 x 2 (Messaging x Incentive) factorial experiment, participants complete a comprehensive set of social and behavioral surveys to identify determinants of commitment to testing. Participants are then randomized to receive customized messaging promoting repeated testing. Messaging will focus upon either (1a) household risk or (1b) personal risk of COVID-19. Participants are also randomly assigned to an incentive condition that either (2a) insures against losing baseline rewards for initial testing, or (2b) entry into a lottery with a small chance to win $150 if both tests are completed. Both the loss protection and lottery conditions carry the same incentive costs. Previous work in similar populations demonstrates that adherence to planned health behaviors is higher with insurance-based incentives than cash payments of equal value. This experiment compares insurance-based incentives to lottery incentives that have been shown to be effective in multiple contexts. Finally, the investigators evaluate if social and behavioral determinants of health result in heterogeneous treatment effects that can inform customization of incentive offerings in future programs devoted to increasing uptake of testing or vaccinations among underserved populations.

Study Design

Study Type:
Interventional
Anticipated Enrollment :
2160 participants
Allocation:
Randomized
Intervention Model:
Factorial Assignment
Masking:
None (Open Label)
Primary Purpose:
Health Services Research
Official Title:
Use of Behavioral Economics in Repeat SARS-CoV-2 (COVID-19) Antibody Testing in Disadvantaged Communities
Actual Study Start Date :
Jun 29, 2021
Anticipated Primary Completion Date :
Feb 1, 2023
Anticipated Study Completion Date :
Mar 1, 2023

Arms and Interventions

Arm Intervention/Treatment
Experimental: Personal Risk + Loss Protection

Personal Risk + Loss Protection

Behavioral: Personal Risk Messaging
Personal risk framing may engender concern for oneself. Households randomized to personal risk messaging will receive the following message: "Antibody testing will help you understand your risk of getting COVID-19."

Behavioral: Loss Protection
Household members are offered a baseline incentive with a 90% (9 in 10) chance of $60 and receive insurance on winning the baseline incentive for repeat antibody testing.

Experimental: Personal Risk + Lottery Incentive

Personal Risk + Lottery Incentive

Behavioral: Personal Risk Messaging
Personal risk framing may engender concern for oneself. Households randomized to personal risk messaging will receive the following message: "Antibody testing will help you understand your risk of getting COVID-19."

Behavioral: Lottery Incentive
Household members are offered a baseline incentive with a 90% (9 in 10) chance of $60 and receive a bonus lottery incentive with a 4 small (1 in 25) chance of winning $150 for repeat antibody testing.

Experimental: Family Risk + Loss Protection

Family Risk + Loss Protection

Behavioral: Family Risk Messaging
Family risk framing may engender concern for loved ones. It may also make it easier to mentally simulate family burdens with COVID-19 such as knowing how several people in the family becoming sick could adversely affect the lives of everyone in the family. Households randomized to family risk messaging will receive the following message: "Antibody testing will help you understand your family's risk of getting COVID-19."

Behavioral: Loss Protection
Household members are offered a baseline incentive with a 90% (9 in 10) chance of $60 and receive insurance on winning the baseline incentive for repeat antibody testing.

Experimental: Family Risk + Lottery Incentive

Family Risk + Lottery Incentive

Behavioral: Family Risk Messaging
Family risk framing may engender concern for loved ones. It may also make it easier to mentally simulate family burdens with COVID-19 such as knowing how several people in the family becoming sick could adversely affect the lives of everyone in the family. Households randomized to family risk messaging will receive the following message: "Antibody testing will help you understand your family's risk of getting COVID-19."

Behavioral: Lottery Incentive
Household members are offered a baseline incentive with a 90% (9 in 10) chance of $60 and receive a bonus lottery incentive with a 4 small (1 in 25) chance of winning $150 for repeat antibody testing.

Outcome Measures

Primary Outcome Measures

  1. Attendance rate at Time 2 SARS-CoV-2 antibody test [6 months]

    Effectiveness of risk-based messaging and incentives to encourage attendance at Time 2 testing for SARS-CoV-2 antibodies

Secondary Outcome Measures

  1. Social and behavioral determinants of antibody testing [6 months]

    Characterize barriers to access, bias, risk attitude and incentive preferences assessed through survey responses

Eligibility Criteria

Criteria

Ages Eligible for Study:
5 Years and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
  • Adults and children 5 years of age and older
Exclusion Criteria:
  • Children under 5 years of age

Contacts and Locations

Locations

Site City State Country Postal Code
1 AltaMed Health Los Angeles California United States 90022

Sponsors and Collaborators

  • University of Southern California
  • AltaMed Health Services
  • National Institute on Aging (NIA)

Investigators

  • Principal Investigator: Jason Doctor, PhD, University of Southern California

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Jason Doctor, Professor, University of Southern California
ClinicalTrials.gov Identifier:
NCT04901624
Other Study ID Numbers:
  • HS-20-00793
  • 3R33AG057395-04S1
First Posted:
May 25, 2021
Last Update Posted:
Jul 13, 2022
Last Verified:
Jul 1, 2022
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Keywords provided by Jason Doctor, Professor, University of Southern California

Study Results

No Results Posted as of Jul 13, 2022