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Feeling of Being in Control of One's Own Action

Sponsor
University Hospital, Strasbourg, France (Other)
Overall Status
Completed
CT.gov ID
NCT01312649
Collaborator
(none)
198
Enrollment
1
Location
5
Arms
74.5
Actual Duration (Months)
2.7
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The investigators aim is to understand the cognitive mechanisms that contribute to the emergence of delusions of control (the belief that one's own actions or thoughts are controlled by an external force). These symptoms are mainly encountered in patients with schizophrenia, and the investigators will distinguish patients with schizophrenia with or without this symptom together with patients with bipolar disorder. Based on the investigators previous studies, this project will help to determine the role of two elementary mechanisms in the ability to feel in control of voluntary actions: (1) the processing of the sensory consequences of action, and (2) the ability to build mental representations for sequenced actions.

Condition or Disease Intervention/Treatment Phase
  • Behavioral: Experimental psychology methods (computer tests)
 N/A

Study Design

Study Type:
Interventional
Actual Enrollment :
198 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Masking:
Single (Outcomes Assessor)
Primary Purpose:
Basic Science
Official Title:
Feeling of Being in Control of One's Own Action: Which Mechanisms in Healthy Volunteers and in Mental Diseases
Actual Study Start Date :
Apr 1, 2011
Actual Primary Completion Date :
Jun 15, 2017
Actual Study Completion Date :
Jun 15, 2017

Arms and Interventions

Arm Intervention/Treatment
Experimental: Arm 1

Healthy volunteers

Behavioral: Experimental psychology methods (computer tests)
Experimental: Arm 2

Schizophrenia with history of delusions of control

Behavioral: Experimental psychology methods (computer tests)
Experimental: Arm 3

Schizophrenia without history of delusions of control

Behavioral: Experimental psychology methods (computer tests)
Experimental: Arm 4

Bipolar disorders

Behavioral: Experimental psychology methods (computer tests)
Active Comparator: Arm 5

Matched healthy controls

Behavioral: Experimental psychology methods (computer tests)

Outcome Measures

Primary Outcome Measures

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years to 55 Years
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    Yes
    Inclusion Criteria:

    • Patients with schizophrenia or bipolar disorders (criteria DSM IV) or healthy controls matched with patients on age, sex and education level

    • 18-55 years old

    Exclusion Criteria:

    • Past history affecting CNS

    • Invalidating sensory disorders

    • Intake of psychotropic drugs, except for patients

    • Intake of benzodiazepines

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Pôle de Psychiatrie - Hôpital civil Strasbourg France

    Sponsors and Collaborators

    • University Hospital, Strasbourg, France

    Investigators

    • Study Director: Anne GIERSCH, MD, Hôpitaux Universitaires de Strasbourg

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    University Hospital, Strasbourg, France
    ClinicalTrials.gov Identifier:
    NCT01312649
    Other Study ID Numbers:
    • 4880
    First Posted:
    Mar 11, 2011
    Last Update Posted:
    Mar 22, 2018
    Last Verified:
    Sep 1, 2017
    Additional relevant MeSH terms:
    Schizophrenia
    Bipolar Disorder

    Study Results

    No Results Posted as of Mar 22, 2018