EMDRpsychose: Interest of EMDR Schizophrenic Disorders
Study Details
Study Description
Brief Summary
The purpose of this study is to determine the interest of the use of EMDR (Eye Movement Desensitization and Reprocessing) psychotherapy in the management of psychotic disorders, in particular schizophrenic disorders.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Detailed Description
Since 2015 more and more studies conducted by researchers, especially Dutch and English, are interested in the use of EMDR (Eye Movement Desensitization and Reprocessing) for other pathologies such as bipolar disorder, unipolar depression, anxiety disorders, psychotic disorders, substance use disorders and chronic pain.
These studies show that EMDR appears to be a technique that is both effective, capable of significantly improving symptoms, and without risk for patients, while respecting the protocol and the clinical stabilization provided during the procedure.
To date, the use of EMDR for the management of psychotic patients has not been the subject of any prospective study in France and the authors' conclusions converge on the fact that it is essential to carry out more research on the subject.
For this, the investigators wish to evaluate the effect of EMDR on the management of patients with schizophrenic disorders, on the basis that this psychotherapy would improve their quality of life (improvement of all the specific scores used in psychiatry). : PANSS, DES, HAD and WEMWBS scales).
Finally, the investigators believe that it is relevant to assess the benefit of EMDR six months after hospitalization of patients, in order to measure the maintenance of this efficacy in the medium term
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Control group Patients in the control group will have simple consultations on D15, D30, D45, D60 and D75 |
Other: Control group
Patients in the control group will have simple consultations on D15, D30, D45, D60 and D75
|
| EMDR group Patients in the EMDR group will have EMDR session on D15, D30, D45, D60 and D75 |
Other: EMDR group
Patients in the EMDR group will have EMDR session on D15, D30, D45, D60 and D75
|
Outcome Measures
Primary Outcome Measures
- Assessment of the decrease in the severity of positive or negative symptoms of schizophrenia [At 6 month after Hospital discharge (M0)]
The decrease in the severity of positive or negative symptoms of schizophrenia is assessed using the "Positive and Negative Syndrome Scale" (PANSS) between M0 and M6.This decrease will be considered effective if it's greater than or equal to 20%.
Secondary Outcome Measures
- Assessment of the decrease in the intensity of dissociative symptoms. [At 6 month after Hospital discharge (M0)]
The decrease in the intensity of dissociative symptoms is assessed using the Dissociative Experience Scale (DES) between M0 and M6. The DES is a short written questionnaire. It consists of 28 items that assess the frequency of various dissociative symptoms in the patient's daily life. 0 corresponds to the answer "Never" and 100 to the answer "All the time". The total score is obtained by adding the scores of the 28 items and then dividing by 28. This gives a score between 0 and 100.
- Assessment of the decrease in the intensity of anxiety and depressive symptoms. [At 6 month after Hospital discharge (M0)]
The decrease in the intensity of anxiety and depressive symptoms is assessed using the Hospital Anxiety and Depression (HAD) between M0 and M6 The HAD scale is a short written questionnaire, consisting of 14 items to assess the patient's symptoms of anxiety and depression. The total anxiety score is obtained by adding the scores of items 1, 3, 5, 7, 9, 11 and 13 and the total depression score by adding the scores of the remaining items. The interpretation of the results is as follows: Score ≤ 7 = absence of symptomatology, 8 ≥ Score ≤ 10 = questionable symptomatology Score ≥ 11 = certain symptomatology.
- Quality of life assessment [At 6 month after Hospital discharge (M0)]
The quality of life is assessed using the Warwick-Edinburgh Mental Well-Being Scale (WEMWBS). The Warwick-Edinburgh Mental Wellbeing Scale (WEMWBS) assesses the psychological well-being of individuals. It consists of 14 items on a likert scale of 5 (1: never, 2: rarely, 3: sometimes, 4: often, 5: all the time). In this scale, there is no threshold score, but the higher the score, the stronger the psychological well-being of the individual. An improvement in the quality of life is measured by an increase in the scale score between M0 and M6
Eligibility Criteria
Criteria
Inclusion Criteria:
-
≥ 18 years and over,
-
Hospitalized for decompensated psychotic disorder, Positive diagnosis of schizophrenia or schizoaffective disorder (according to the DSM-V psychiatry manual),
-
With positive or negative symptoms according to the Positive and Negative Syndrome Scale (PANSS),
-
Stabilized clinical condition (considered compatible with hospital discharge),
-
With ambulatory follow-up planned after hospitalization
Exclusion Criteria:
-
< 18 years,
-
Patients who do not meet the diagnostic criteria (according to the DSM-V psychiatry manual) for schizophrenic or schizoaffective disorder),
-
Non-French speaking or illiterate patients,
-
Cognitive disorders making it impossible the understanding and the none- opposition to the study,
-
Non-stabilized clinical condition (incompatible with hospital discharge),
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Departement of Psychiatry - Hospital René Dubos | Pontoise | France | 95300 | |
| 2 | Departement of Psychiatry -Hospital Paul Guiraud | Villejuif | France | 94800 |
Sponsors and Collaborators
- Centre Hospitalier René Dubos
Investigators
- Principal Investigator: Dr Marie-Claire ASMAR, Hospital René Dubos - Pontoise
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- CHRD 1721