Observing the Morphology of Schlemm's Canal and Crystalline Lens in Different Age
Sponsor
Wenzhou Medical University (Other)
Overall Status
Completed
CT.gov ID
NCT04360161
Collaborator
(none)
80
1
1
5.4
14.8
Study Details
Study Description
Brief Summary
The aim of this study is to quantify and observe the morphology of trabecular meshwork (TM), Schlemm's canal (SC), ciliary body and crystalline lens before and after cycloplegia in patients with different ages using swept-source optical coherence tomography.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
N/A |
Study Design
Study Type:
Interventional
Actual Enrollment
:
80 participants
Allocation:
N/A
Intervention Model:
Single Group Assignment
Masking:
None (Open Label)
Primary Purpose:
Prevention
Official Title:
Morphology of Schlemm's Canal and Crystalline Lens in Different Age: a Swept-source Optical Coherence Tomography Study
Actual Study Start Date
:
Aug 8, 2019
Actual Primary Completion Date
:
Dec 20, 2019
Actual Study Completion Date
:
Jan 20, 2020
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Experimental: Healthy participants Swept-source optical coherence tomography A device testing TM/SC and Lens morphology |
Device: swept-source optical coherence tomography
Aswe pt-source OCT (CASIA SS-1000; Tomey Corporation, Nagoya, Japan), which is specifically designed for anterior segment imaging using a 1310 nm wavelength with a scan speed of 30,000 A-scans per second and an axial resolution of <10 μm.
|
Outcome Measures
Primary Outcome Measures
- area of Schlemm's canal and trabecular meshwork [up to 6 months]
The area of Schlemm's canal and trabecular meshwork was manually measured and the relationship between the parameters and age was analyzed.
Eligibility Criteria
Criteria
Ages Eligible for Study:
7 Years
to 60 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
- healthy patients who can cooperated with the swept-source OCT measurements
Exclusion Criteria:
-
history of ocular disease
-
presence of central nervous system or systemic disease
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Eye Hospital of WMU | Hangzhou | Zhejiang | China | 325027 |
Sponsors and Collaborators
- Wenzhou Medical University
Investigators
- Study Director: Yune Zhao, Eye Hospital of Wenzhou Medical University
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
Yune Zhao,
Director of Cataract Department,
Wenzhou Medical University
ClinicalTrials.gov Identifier:
NCT04360161
Other Study ID Numbers:
- TM/SC/Lens-LZL
First Posted:
Apr 24, 2020
Last Update Posted:
Apr 24, 2020
Last Verified:
Apr 1, 2020
Individual Participant Data (IPD) Sharing Statement:
No
Plan to Share IPD:
No
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No