Scleral Hydrops and Intralabyrinthine Schwannoma
Study Details
Study Description
Brief Summary
The symptoms of intralabyrinthine schwannomas (vertigo, deafness, instability, tinnitus) cut across the symptoms found in pressure pathologies involving the inner ear, particularly the endolymphatic hydrops.
Some publications have described dilatation of the membranous labyrinth (hydrops) in the presence of intralabyrinthine tumors.
It would be interesting to measure the size of the saccule (structure of the membranous labyrinth) in the presence of an intralabyrinthine schwannoma, to evaluate if some of the symptoms presented by the patients could be explained by the concomitant presence of an endolymphatic hydrops (accessible to drug therapy - Betahistine).
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
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Study Design
Outcome Measures
Primary Outcome Measures
- Size of intralabyrinth saccules [1 hour after the realization of the MRI]]
To measure saccule size (membranous labyrinth structure) in patients with intralabyrinthine schwannoma on a high resolution fluid sequence (FIESTA-C) in 3T MRI
Eligibility Criteria
Criteria
Inclusion Criteria
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Age> 18,
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Subject having benefited from an exploration of internal auditory canals by MRI in our service at CHU de Hautepierre between January 1, 2008 and October 1, 2017
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Presence on the MRI of the internal auditory ducts, including the realization of a high resolution fluid sequence of FIESTA-C (exploitable) type, of an intralabyrinthine schwannoma, without extension to the internal auditory canal.
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Subject who has agreed to the use of medical data for the purposes of this research.
Criteria for Non Inclusion
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Refusal of the patient to participate in the study
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Absence of high resolution fluid sequence of fast imaging employing steady state acquisition (FIESTA-C)
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Presence of movement artifacts interfering with the interpretation of the FIESTA-C sequence
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Interior surgery of the inner ear or pontocerebellar angle, without preoperative imaging Inflammatory or infectious pathology of the concomitant middle or inner ear
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Extension of schwannoma to the internal auditory canal
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Impossibility of giving the subject informed information (difficulty understanding the subject,)
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Subject under the protection of justice
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Subject under guardianship or curatorship
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Service Imagerie 1 | Strasbourg | France | 67091 |
Sponsors and Collaborators
- University Hospital, Strasbourg, France
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- 7026