Interrupting Sitting Time During Postprandial State

Sponsor

Franklin Pierce University (Other)

Overall Status

Completed

CT.gov ID

NCT04590729

Collaborator

(none)

Enrollment

Location

Arms

Actual Duration (Months)

10.8

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The literature has shown that interrupting sitting time with frequent physical activities (e.g., cycling on a stationary bike for 3 minutes every 30 minutes of sitting) is effective for decreasing blood sugar levels. However, the optimal frequency and distribution of sitting interruption remains less clear. The purpose of this study is to compare the effects of two different protocols of sitting interruption (i.e., 3 minutes of cycling every 30 minutes versus 3 minutes of cycling every 15 minutes) on blood sugar levels.

Condition or Disease	Intervention/Treatment	Phase
Sedentary Behavior	Behavioral: 3-min Exercise Per 30 Min Behavioral: 3-min Exercise Per 15 Min	N/A

Detailed Description

This study will involve two different physical activity conditions and a control condition. Each participant will undergo the three conditions in a random order. The first protocol involves 3 minutes of cycling on a stationary bike at moderate intensity every 30 minutes for 6 hours, totaling 36 minutes of cycling exercise. The second protocol involves 3 minutes of cycling on a stationary bike at moderate intensity every 15 minutes for 3 hours to match the total exercise duration in the first protocol. Participants will remain seated for 3 hours to match to the total time spent in the lab. For the control condition, participants will remain seated. For each condition, participants will be provided with two meals, one before the protocol and another one in the middle of the protocol. The meals will be purchased from the cafeteria on campus based on the participant's own choice as long as carbohydrates account for 55-65% of total calories. Participants will eat identical meals across the three conditions.

Study Design

Study Type:

Interventional

Actual Enrollment :

11 participants

Allocation:

Randomized

Intervention Model:

Crossover Assignment

Intervention Model Description:

three-by-three crossover designthree-by-three crossover design

Masking:

Triple (Participant, Investigator, Outcomes Assessor)

Primary Purpose:

Treatment

Official Title:

Redistributing Intermittent Physical Activity Breaks to Target Postprandial Glucose Excursion.

Actual Study Start Date :

Oct 20, 2020

Actual Primary Completion Date :

Nov 20, 2020

Actual Study Completion Date :

Nov 20, 2020

Arms and Interventions

Arm	Intervention/Treatment
Experimental: 3-min Exercise Per 30 Min This protocol involves 3 minutes of cycling on a stationary bike at moderate intensity every 30 minutes for 6 hours, totaling 36 minutes of cycling exercise.	Behavioral: 3-min Exercise Per 30 Min This protocol involves 3 minutes of cycling on a stationary bike at 50 revolutions per minute and 1 kilopond every 30 minutes for 6 hours, totaling 36 minutes of cycling exercise.
Experimental: 3-min Exercise Per 15 Min This protocol involves 3 minutes of cycling on a stationary bike at moderate intensity every 15 minutes for 3 hours to match the total exercise duration in the first protocol.	Behavioral: 3-min Exercise Per 15 Min This protocol involves 3 minutes of cycling on a stationary bike at 50 revolutions per minute and 1 kilopond every 15 minutes for 3 hours, totaling 36 minutes of cycling exercise.
No Intervention: Sitting Sitting control.

Arm

Intervention/Treatment

Experimental: 3-min Exercise Per 30 Min

This protocol involves 3 minutes of cycling on a stationary bike at moderate intensity every 30 minutes for 6 hours, totaling 36 minutes of cycling exercise.

Behavioral: 3-min Exercise Per 30 Min

This protocol involves 3 minutes of cycling on a stationary bike at 50 revolutions per minute and 1 kilopond every 30 minutes for 6 hours, totaling 36 minutes of cycling exercise.

Experimental: 3-min Exercise Per 15 Min

This protocol involves 3 minutes of cycling on a stationary bike at moderate intensity every 15 minutes for 3 hours to match the total exercise duration in the first protocol.

Behavioral: 3-min Exercise Per 15 Min

This protocol involves 3 minutes of cycling on a stationary bike at 50 revolutions per minute and 1 kilopond every 15 minutes for 3 hours, totaling 36 minutes of cycling exercise.

No Intervention: Sitting

Sitting control.

Outcome Measures

Primary Outcome Measures

Postprandial glucose levels [three and a half hour after the carbohydrates intake]
The investigators will measure capillary blood sugar levels every 30 minutes using the finger-stick method.

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years to 45 Years

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Yes

Inclusion Criteria:

Apparently healthy persons
Sedentary lifestyle

Exclusion Criteria:

Cardiovascular diseases
Pulmonary diseases
Metabolic diseases
Other contraindications to exercise

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Franklin Pierce University	Rindge	New Hampshire	United States	03461

Sponsors and Collaborators

Franklin Pierce University

Investigators

Principal Investigator: Tongyu Ma, Ph.D., Franklin Pierce University

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

Responsible Party:

Tongyu Ma, Assistant Professor of Health Sciences, Franklin Pierce University

ClinicalTrials.gov Identifier:

NCT04590729

Other Study ID Numbers:

TM9282020

First Posted:

Oct 19, 2020

Last Update Posted:

Nov 24, 2020

Last Verified:

Nov 1, 2020

Individual Participant Data (IPD) Sharing Statement:

Plan to Share IPD:

Studies a U.S. FDA-regulated Drug Product:

Studies a U.S. FDA-regulated Device Product:

Study Results

No Results Posted as of Nov 24, 2020