Short Term Results of Pediatric Septic Hip Arthritis Management in Assiut University Hospitals

Sponsor
Assiut University (Other)
Overall Status
Not yet recruiting
CT.gov ID
NCT05780697
Collaborator
(none)
50
1
24

Study Details

Study Description

Brief Summary

Detect short term results of pediatric septic hip arthritis and its risk factors

Condition or Disease Intervention/Treatment Phase
  • Procedure: Surgery of Drainage of septic hip arthritis
N/A

Detailed Description

Septic arthritis of the hip is a true orthopedic emergency(1). In developed countries, the incidence of acute bacterial septic arthritis is estimated to be 4 to 10 per 100,000 children (2).It is caused by many microorganisms. Staph aureus is most common in children over 2 years of age . Staph aureus is gram-positive cocci in clusters and most common in nosocomial infections of neonates(3-4).Group B streptococcus is most common in neonates with community-acquired infection and exposed during transvaginal delivery(5).Neisseria gonorrhoeae is gram-negative diplococci and most common in adolescents.when the causative Organism is Neisseria gonorrhoeae ,patients usually have a preceding migratory polyarthralgia,multiple joint involvement and small red papules(6-7).Group A beta-hemolytic streptococcus is most common organism following varicella infection.HACEK organisms (Haeophilus,Actinobacillus,Cardiobacterium,Eikenella,and Kingella fastidious) are less common causative organisms(8-9).Early diagnosis and accurate treatment is key in avoiding complications such as joint destruction,joint dislocation , ankylosis, growth arrest or spread of infection leading to osteomyelitis , pelvic abscess or nerve lesions.. Treatment is started without delay after synovial fluid and blood samples have been obtained. The classical presentation of septic hip arthritis in children is a combination of a painful hip joint with limited range of motion, fever, malaise and inability to bear weight on the affected limb. Misdiagnosis or inappropriate treatment of acute septic arthritis of the hip in children can result in devastating damage of the joint and possible lifelong disability. Open arthrotomy , drainage and thorough irrigation of the joint is considered the standard treatment for septic arthritis of the hip.Empiric antibiotic treatment primarily targets S. aureus and takes into account its resistance to antibiotics(10-11). So,we want to detect short term results of pediatric septic hip arthritis at Assiut University Hospitals

Study Design

Study Type:
Interventional
Anticipated Enrollment :
50 participants
Allocation:
N/A
Intervention Model:
Single Group Assignment
Masking:
None (Open Label)
Primary Purpose:
Treatment
Official Title:
Short Term Results of Pediatric Septic Hip Arthritis Management in Assiut University Hospitals
Anticipated Study Start Date :
Mar 1, 2023
Anticipated Primary Completion Date :
Mar 1, 2024
Anticipated Study Completion Date :
Mar 1, 2025

Arms and Interventions

Arm Intervention/Treatment
Experimental: Children presented with septic hip arthritis in Assiut University Hospitals

Surgery of Drainage of pus in septic hip arthritis

Procedure: Surgery of Drainage of septic hip arthritis
Surgery for septic hip arthritis by anterior or lateral approach and inspection of femoral head

Outcome Measures

Primary Outcome Measures

  1. Modified Moon's criteria for outcome assessment of hip function [Baseline]

Secondary Outcome Measures

  1. Detection of Complications [Baseline]

    Complications such as limb-lenght discrepancy , Avascular necrosis of the femoral head and hip destruction will be documented

Eligibility Criteria

Criteria

Ages Eligible for Study:
1 Day to 14 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
  • Children younger than 14 years old presented with septic hip arthritis only or by bilateral septic hip arthritis in Assiut University Hospitals
Exclusion Criteria:
  • 1-patients with Tuberculous arthritis 2-patients whose parents refuse to participate in the study

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

  • Assiut University

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

Responsible Party:
Beshoy Elkess Ibram, Resident Dr, Assiut University
ClinicalTrials.gov Identifier:
NCT05780697
Other Study ID Numbers:
  • Pediatric Septic Hip arthritis
First Posted:
Mar 22, 2023
Last Update Posted:
Mar 22, 2023
Last Verified:
Mar 1, 2023
Individual Participant Data (IPD) Sharing Statement:
No
Plan to Share IPD:
No
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms:

Study Results

No Results Posted as of Mar 22, 2023