Serum Hepcidin, Haemoglobin Level and Iron Status in Chronic Kidney Disease Patients (CKD) With Anaemia
Sponsor
Assiut University (Other)
Overall Status
Not yet recruiting
CT.gov ID
NCT04102319
Collaborator
(none)
64
50
Study Details
Study Description
Brief Summary
The current study is planned to assess possible relationships of serum hepcidin levels with haemoglobin levels, inflammation and iron statuses in stage 4 CKD patients.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Study Design
Study Type:
Observational
Anticipated Enrollment
:
64 participants
Observational Model:
Case-Control
Time Perspective:
Cross-Sectional
Official Title:
Association Between Hepcidin, Haemoglobin Level and Iron Status in Stage 4 Chronic Kidney Disease Patients With Anaemia
Anticipated Study Start Date
:
Oct 1, 2019
Anticipated Primary Completion Date
:
Oct 1, 2022
Anticipated Study Completion Date
:
Dec 1, 2023
Outcome Measures
Primary Outcome Measures
- relation between serum hepcidin level and ESR ckd stage 4 [at study entry and then again after 3 months]
measure strength of relation, r, between levels of serum hepcidin and ESR, an inflammation marker
- relation between serum hepcidin and serum ferritin levels [at study entry and then again after 3 months]
measure strength of relation, r, between levels of hecidin and ferritin
Eligibility Criteria
Criteria
Ages Eligible for Study:
18 Years
and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
- Adult patients (>18 years) with anaemia who had CKD stage 4 with glomerular filtration rate (GFR) 15-29 ml/min/1.73 m2
Exclusion Criteria:
- Subjects with blood transfusion within the preceding 3 months. myocardial infarction (MI) history within the preceding 3 months, surgical history within the preceding 3 months, malignancy. Advanced liver cirrhosis. uncontrolled diabetes
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- Assiut University
Investigators
- Principal Investigator: Mohamed Hamed, MD, Assiut University
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
Deiaaeldeen Masaoud Sadeq Mohammed,
Dr,
Assiut University
ClinicalTrials.gov Identifier:
NCT04102319
Other Study ID Numbers:
- hepcidin,Anemia
First Posted:
Sep 25, 2019
Last Update Posted:
Sep 25, 2019
Last Verified:
Sep 1, 2019
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms: