Serum Zinc, Peptic Ulcer Disease and H. Pylori Infection

• Sponsor: Ain Shams University (Other)
• Overall Status: Completed
• CT.gov ID: NCT02716025
• Collaborator: (none)
• Enrollment: 75
• Duration (Months): 22

Study Details

Study Description

Brief Summary

Fifty consecutive patients with symptoms suggestive of peptic ulcer disease were included. All underwent complete clinical evaluation, laboratory investigations, upper gastrointestinal endoscopy and rapid urease test. Measurement of serum zinc level was done for all the included patients in addition to twenty five age and sex matched healthy control subjects.

Condition or Disease	Intervention/Treatment	Phase
Peptic Ulcer Disease	Procedure: Upper gastrointestinal endoscopy

Study Design

• Study Type: Observational
• Actual Enrollment: 75 participants
• Observational Model: Case-Control
• Time Perspective: Prospective
• Study Start Date: Oct 1, 2013
• Actual Primary Completion Date: Aug 1, 2015
• Actual Study Completion Date: Aug 1, 2015

Arms and Interventions

Arm	Intervention/Treatment
Case Group	Procedure: Upper gastrointestinal endoscopy; Thorough examination of the esophagus, stomach and duodenum to the second part was done to all patients using Olympus CV-150 or Pentax EPM-3500.
Control Group

Outcome Measures

Primary Outcome Measures

1. Detection of positive upper GIT endoscopic findings [upon endoscopy]

Eligibility Criteria

Criteria

• Ages Eligible for Study: 18 Years to 55 Years
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:

• Symptoms suggestive of peptic ulcer disease like epigastric pain, dyspepsia, heartburn

Exclusion Criteria:

• Patients who received zinc supplementation, proton pump inhibitors (PPI), non-steroidal anti-inflammatory drugs (NSAIDs)

• Those presented with hematemesis or melena

• Those with chronic liver disease, renal failure, malabsorption or previous gastric surgery

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

• Ain Shams University

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: Sara Abdelhakam, Assistant Professor, Ain Shams University
• ClinicalTrials.gov Identifier: NCT02716025
• Other Study ID Numbers: 811
• First Posted: Mar 22, 2016
• Last Update Posted: Mar 22, 2016
• Last Verified: Mar 1, 2016

• Additional relevant MeSH terms: Peptic Ulcer

Study Results

No Results Posted as of Mar 22, 2016