Evaluation of Sestrin Levels in Patients With Endometriosis

• Sponsor: Kanuni Sultan Suleyman Training and Research Hospital (Other)
• Overall Status: Completed
• CT.gov ID: NCT04886037
• Collaborator: (none)
• Enrollment: 90
• Location: 1
• Actual Duration (Months): 5.6
• Patients Per Site Per Month: 16.2

Study Details

Study Description

Brief Summary

Serum sestrin levels of endometriosis patients are compared with a group of healthy volunteers of the same age.

Condition or Disease	Intervention/Treatment	Phase
Endometriosis	Other: sestrin

Detailed Description

Serum sestrin levels are compared with 45 endometriosis patients and 45 healthy volunteers of the same age. The energy metabolism of the endometriosis group and its possible relationship with the endometriosis stage will be compared since sestrin gives information about the energy metabolism of the people.

Study Design

• Study Type: Observational
• Actual Enrollment: 90 participants
• Observational Model: Case-Control
• Time Perspective: Prospective
• Official Title: The Sestrin Levels in Patients With Endometriosis
• Actual Study Start Date: Feb 1, 2021
• Actual Primary Completion Date: Jul 10, 2021
• Actual Study Completion Date: Jul 20, 2021

Arms and Interventions

Arm	Intervention/Treatment
women with endometriosis It consists of women between the ages of 18-45 who have been diagnosed with endometriosis by surgery or ultrasonography.	Other: sestrin; Serum sestrin levels involved in inflammation and energy metabolism are compared between endometriosis and healthy control group.
control It consists of healty women between the ages of 18-45	Other: sestrin; Serum sestrin levels involved in inflammation and energy metabolism are compared between endometriosis and healthy control group.

Outcome Measures

Primary Outcome Measures

1. Serum sestrin levels in women with endometriosis [6 months]

   Serum sestrin levels involved in inflammation and energy metabolism are compared between endometriosis and healthy control group.

Secondary Outcome Measures

1. Comparison of the relationship between serum sestrin level and endometriosis stage [6 months]

   By comparing the relation of serum sestrin level with the stage of endometriosis, its relation with serum level in patients with advanced and early stage endometriosis will be examined. The possible effect of sestrin on disease pathogenesis will be examined.

Eligibility Criteria

Criteria

• Ages Eligible for Study: 18 Years to 45 Years
• Sexes Eligible for Study: Female
• Accepts Healthy Volunteers: Yes

Inclusion Criteria:

• diagnosed with endometriosis (Surgery or ultrasound)

• Women without endometriosis

Exclusion Criteria:

• Women without endometriosis

• women who are only suspected endometriosis

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Pinar Yalcin Bahat	Istanbul	İ̇stanbul	Turkey	34000

Sponsors and Collaborators

• Kanuni Sultan Suleyman Training and Research Hospital

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: Pınar Yalcin bahat, Principal Investigator, Kanuni Sultan Suleyman Training and Research Hospital
• ClinicalTrials.gov Identifier: NCT04886037
• Other Study ID Numbers: endo-sestrin
• First Posted: May 13, 2021
• Last Update Posted: Aug 31, 2021
• Last Verified: Aug 1, 2021

• Individual Participant Data (IPD) Sharing Statement: Undecided
• Plan to Share IPD: Undecided
• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No
• Keywords provided by Pınar Yalcin bahat, Principal Investigator, Kanuni Sultan Suleyman Training and Research Hospital: sestrin
• Additional relevant MeSH terms: Endometriosis

Study Results

No Results Posted as of Aug 31, 2021