Clincosm LogoSign in Get a demo

CASC: Community Acquired Sepsis Cohort

Sponsor
Rennes University Hospital (Other)
Overall Status
Terminated
CT.gov ID
NCT03280992
Collaborator
(none)
796
Enrollment
1
Location
29.8
Actual Duration (Months)
26.7
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The aim of this project is to constitute a prospective cohort of all the patients presenting to the adult emergencies of the University Hospital Centre (CHU) of Rennes for a septic syndrome of community origin.

Condition or Disease Intervention/Treatment Phase

    Detailed Description

    Severe septic syndrome (SSG) and septic shock (CS) are two frequent and serious complications of infectious diseases. In this context, the optimization of the management of septic patients from their reception in the emergency services must be a priority. However there are no predictors of progression or severity in patients admitted to emergencies despite the recommendations emphasizing the need for screening and early therapeutic management. Many scores have been proposed for intensive care unit but they remain difficult to extrapolate to other services because they are very comprehensive and require information that is difficult to obtain for emergency physicians.

    Study Design

    Study Type:
    Observational [Patient Registry]
    Actual Enrollment :
    796 participants
    Observational Model:
    Cohort
    Time Perspective:
    Prospective
    Official Title:
    Community Acquired Sepsis Cohort
    Actual Study Start Date :
    Mar 2, 2016
    Actual Primary Completion Date :
    Aug 27, 2018
    Actual Study Completion Date :
    Aug 27, 2018

    Outcome Measures

    Primary Outcome Measures

    1. Assessment of morbidity in patients with septic syndrome of community origin [Day 90]

      Study of prognostic factors

    2. Internal validity, severity score [Day 90]

    3. Internal validity, triage score by orientation nurses [Day 90]

    4. Study of the prognostic factors of patients with septic syndrome of community origin in terms of mortality [Day 90]

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years and Older
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    No
    Inclusion Criteria:

    • Patient older than 18 years old

    • Patient hospitalized during the study period for community infectious diseases at the CHU of Rennes

    Exclusion Criteria:

    • Written objection from the patient to the computer processing of his data

    • Pregnant women

    • Persons subject to major legal protection (safeguarding justice, guardianship, trusteeship), persons deprived of liberty

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 CHU de Rennes Rennes France 35033

    Sponsors and Collaborators

    • Rennes University Hospital

    Investigators

    None specified.

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    Rennes University Hospital
    ClinicalTrials.gov Identifier:
    NCT03280992
    Other Study ID Numbers:
    • 35RC16_3024_CASC
    First Posted:
    Sep 13, 2017
    Last Update Posted:
    Dec 2, 2021
    Last Verified:
    Dec 1, 2021
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No
    Additional relevant MeSH terms:
    Shock, Septic
    Systemic Inflammatory Response Syndrome

    Study Results

    No Results Posted as of Dec 2, 2021