Shanghai Ovarian Cancer and Family Care Project
Study Details
Study Description
Brief Summary
Ovarian cancer is the most lethal gynaecological malignancy, but its incidence in the general population is low. Due to the lack of effective prevention and successful screening approaches, most cases are diagnosed at advanced stages, leading to poor prognosis. In order to address the research requirements pertaining to ovarian cancer, the Shanghai Ovarian Cancer and Family Care Project was established. This initiative offers hospital-based resources for investigating ovarian cancer and high-risk populations. The project comprises an on-going ovarian cancer cohort, a high-risk population cohort, and a healthy population cohort. By leveraging these comprehensive cohorts, the project provides a unique platform for in-depth studies on the detection, prevention, early diagnosis, treatment, and prognosis of ovarian cancer.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
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Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Ambispective patient cohort Patients attending the oncology department require differential diagnosis of ovarian cancer. |
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| High-risk population cohort Family members of ovarian cancer patients; family history of BRCA mutation-related disease; abnormal findings on ovarian cancer screening; history of ovarian disease and other risk factors. |
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| Healthy control cohort Healthy women with normal health examination results. |
Outcome Measures
Primary Outcome Measures
- Death due to ovarian cancer [From diagnosis of ovarian cancer until October 31, 2028.]
Death due to ovarian cancer determined by independent outcomes committee.
Eligibility Criteria
Criteria
Participant meet the criteria for one of the following conditions:
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Patients attending the oncology department require differential diagnosis of ovarian cancer.
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Patients with known high-risk factors for ovarian cancer, such as history of ovarian cancer or BRCA-associated cancer, etc.
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Patients attending the Physical Examination Center who have normal findings on physical examination and no symptoms.
Exclusion Criteria:
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Individuals with evidence of another active cancer.
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Individuals who have prior bilateral oophorectomy.
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Individuals who are unwilling or unable to sign the informed consent form.
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Shanghai first maternity and infant hospital | Shanghai | Shanghai | China | 200120 |
Sponsors and Collaborators
- Shanghai First Maternity and Infant Hospital
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- KS23259