Is the Short Physical Performance Battery a Useful Outcome Measure in Chronic Obstructive Pulmonary Disease

Sponsor

Royal Brompton & Harefield NHS Foundation Trust (Other)

Overall Status

Completed

CT.gov ID

NCT01515709

Collaborator

Medical Research Council (Other)

445

Enrollment

Location

Actual Duration (Months)

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Patients with Chronic Obstructive Lung Disease (COPD) often develop muscle problems, particularly in their legs which makes them more limited in what they can do. The Short Physical Performance Battery (SPPB) is a simple test of standing balance, usual walking speed and ability to stand from a chair. The SPPB may be a useful measure to predict leg function.

This study aims to evaluate whether the SPPB is comparable with current exercise tests used in COPD patients, and whether it is useful in predicting disability, death and health resource usage over time.

Condition or Disease	Intervention/Treatment	Phase
Pulmonary Disease, Chronic Obstructive Lung Diseases, Obstructive Pulmonary Emphysema Bronchitis, Chronic Lung Diseases Disease Progression

Study Design

Study Type:

Observational

Actual Enrollment :

445 participants

Observational Model:

Cohort

Time Perspective:

Prospective

Official Title:

Is the Short Physical Performance Battery a Useful Outcome Measure in Patients With Chronic Obstructive Pulmonary Disease ?

Actual Study Start Date :

Apr 1, 2011

Actual Primary Completion Date :

Sep 1, 2013

Actual Study Completion Date :

Sep 1, 2018

Arms and Interventions

Arm	Intervention/Treatment
Chronic Obstructive Pulmonary Disease Patients with a diagnosis of COPD

Outcome Measures

Primary Outcome Measures

Mortality rate [36 months]

Secondary Outcome Measures

Hospitalisation rate [36 months]
Healthcare resource usage [36 months]

Eligibility Criteria

Criteria

Ages Eligible for Study:

N/A and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria:

Diagnosis of COPD

Exclusion Criteria:

Any patient in whom mobility and lower limb function have been significantly affected by a neuromuscular cause (eg. motor neurone disease), severe peripheral vascular disease or amputation
Any patient whom is deemed unsafe to exercise
Patients unable to complete the SPPB, walking tests and leg strength assessments.