Influence of Coffeeberry Ingestion on Soccer Skill Performance

Sponsor

PepsiCo Global R&D (Industry)

Overall Status

Completed

CT.gov ID

NCT04181619

Collaborator

(none)

Enrollment

Location

Arms

20.9

Actual Duration (Months)

1.4

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The study of soccer skill performance has 3 objectives. Objective 1 is to compare effects of coffeeberry (300mg) and placebo ingestion on dribbling speed and precision and passing and shooting speed and accuracy compared to placebo. 30 subjects will be assessed before dosing, after a 1 hr resting absorption period, and after simulated soccer match play. Of these 30, 20 subjects will proceed to Objective 2 (45 minutes of intense simulated soccer match play) and Objective 3 (repeated sprint activity continued until volitional fatigue).

Condition or Disease	Intervention/Treatment	Phase
Skill Performance Soccer Performance Coffeeberry Effects	Dietary Supplement: Coffeeberry beverage Other: Comparator beverage	N/A

Study Design

Study Type:

Interventional

Actual Enrollment :

30 participants

Allocation:

Randomized

Intervention Model:

Crossover Assignment

Masking:

Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)

Masking Description:

Double-blind

Primary Purpose:

Basic Science

Official Title:

Influence of Coffeeberry Extract on Soccer Specific Skill Performance After Rest, During Simulated Soccer Match Play, and Following Fatiguing Exercise in Academy Football Players

Actual Study Start Date :

Nov 6, 2019

Actual Primary Completion Date :

Aug 3, 2021

Actual Study Completion Date :

Aug 3, 2021

Arms and Interventions

Arm	Intervention/Treatment
Experimental: Coffeeberry beverage 300 mg Coffeeberry extract in 300 ml beverage	Dietary Supplement: Coffeeberry beverage One exposure of 300 mg coffeeberry extract in a 300 ml flavored still beverage prior to exercise session
Placebo Comparator: Color and flavor matched beverage 0 mg Coffeeberry extract in 300 ml flavor and color-matched beverage	Other: Comparator beverage One 300 ml still beverage, color and flavor matched to experimental beverage prior to exercise session

Arm

Intervention/Treatment

Experimental: Coffeeberry beverage

300 mg Coffeeberry extract in 300 ml beverage

Dietary Supplement: Coffeeberry beverage

One exposure of 300 mg coffeeberry extract in a 300 ml flavored still beverage prior to exercise session

Placebo Comparator: Color and flavor matched beverage

0 mg Coffeeberry extract in 300 ml flavor and color-matched beverage

Other: Comparator beverage

One 300 ml still beverage, color and flavor matched to experimental beverage prior to exercise session

Outcome Measures

Primary Outcome Measures

Dribbling speed [During 3.5 hours post consumption]
m/sec, increase would be better. Simulated match in an indoor gym with pre-set targets.
Dribbling precision [During 3.5 hours post consumption]
Meters, more accuracy would be better. Simulated match in an indoor gym against pre-set targets.
Passing accuracy [During 3.5 hours post consumption]
1-10 scale, higher score would be better. Simulated match in an indoor gym against pre-set targets.
Passing speed by Time [During 3.5 hours post consumption]
km/h, increased would be better. Simulated match in an indoor gym against pre-set targets.
Shooting accuracy [During 3.5 hours post consumption]
More shots on target would be better. Simulated match in an indoor gym against pre-set targets.
Shooting speed [During 3.5 hours post consumption]
Milliseconds, faster would be better. Simulated match in an indoor gym against pre-set targets.

Secondary Outcome Measures

Sprint speed [During 3.5 hours post consumption]
m/sec, increase would be better. In indoor gym with marked course.
High-intensity endurance running capacity [During 3.5 hours post consumption]
Run time to volitional fatigue in min, increase would be better. In indoor gym with marked course.

Other Outcome Measures

Blood analyte concentration: Capillary glucose [During 3.5 hours post consumption]
(mmol/L), more regulated would be better
Blood analyte concentration: Capillary lactate [During 3.5 hours post consumption]
(mmol/L), lower (delayed rise) would be better
Blood analyte concentration: Serum chlorogenic acid [During 3.5 hours post consumption]
(mmol/L), n.a. for placebo, introduced to evaluate primary outcomes
Blood analyte concentration: Serum caffeine [During 3.5 hours post consumption]
(ug/mL), n.a. for placebo, Introduced to evaluate primary outcomes
Rate of Perceived Exertion (RPE) [During 3.5 hours post consumption]
By Borg scale, rated 6-20, lower values would be better
Activation/Deactivation (feelings and mood) [During 3.5 hours post consumption]
Checklist of feelings using a 4 point scale from definitely do to definitely don't feel, more relaxed and better mood would be better
Mental energy [During 3.5 hours post consumption]
By Visual Analog Scale (VAS) vertical marking on 100 mm horizontal line, higher energy would be better
Physical energy [During 3.5 hours post consumption]
By Visual Analog Scale (VAS) vertical marking on 100 mm horizontal line, higher energy would be better
Heart rate [During 3.5 hours post consumption]
By electronic reading, lower would be better
Gut comfort [During 3.5 hours post consumption]
By Visual Analog Scale (VAS) vertical marking on 100 mm horizontal scale, no or less nausa, fullness or bloating would be better
Hydration status [During 3.5 hours post consumption]
Urine osmolality in mOsm/kg, comparing pre- vs. post-exercise concentration

Eligibility Criteria

Criteria

Ages Eligible for Study:

16 Years to 28 Years

Sexes Eligible for Study:

Male

Accepts Healthy Volunteers:

Yes

Inclusion Criteria:

Provide valid informed consent prior to any study procedure
Male soccer players age 16 to 28 years
5-year soccer playing experience
1-year regularly soccer training
Free of injuries
Willing to avoid alcohol in the 48-h period prior to main trials.
Willing to avoid caffeine, caffeinated and decaffeinated products, apples, and, berries/cherries for 24-h prior to main trials
Willing to record food intake over the 48-h period prior to the first trial and replicate for second trial
Willing to abstain from strenuous physical activity for 24-h before all visits