Hydrolyzed Collagen Combined With Djulis and Green Caviar Improve Skin Condition

• Sponsor: TCI Co., Ltd. (Industry)
• Overall Status: Completed
• CT.gov ID: NCT04709588
• Collaborator: (none)
• Enrollment: 50
• Location: 1
• Arms: 2
• Actual Duration (Months): 4
• Patients Per Site Per Month: 12.5

Study Details

Study Description

Brief Summary

Collagen combined with djulis and green caviar improve skin condition

Condition or Disease	Intervention/Treatment	Phase
Skin Condition	Dietary Supplement: placebo group; Dietary Supplement: collagen drinkss	N/A

Detailed Description

Using collagen drinks combined fish collagen with djulis, and green caviar to improve skin condition.

Study Design

• Study Type: Interventional
• Actual Enrollment: 50 participants
• Allocation: Randomized
• Intervention Model: Parallel Assignment
• Masking: None (Open Label)
• Primary Purpose: Treatment
• Official Title: Hydrolyzed Collagen Combined With Djulis and Green Caviar Improve Skin Condition
• Actual Study Start Date: May 1, 2020
• Actual Primary Completion Date: Jun 30, 2020
• Actual Study Completion Date: Aug 31, 2020

Arms and Interventions

Arm	Intervention/Treatment
Placebo Comparator: placebo group subjects drank 50 ml every night for 14, 28 days	Dietary Supplement: placebo group; subjects drank 50 ml every night for 14, 28 days
Experimental: collagen drinks subjects drank 50 ml every night for 14, 28 days	Dietary Supplement: collagen drinkss; subjects drank 50 ml every night for 14, 28 days

Outcome Measures

Primary Outcome Measures

1. skin moisture [subjects drank 50 ml every night for 28 days]

   using corneometer CM825 to examine skin moisture (The higher the value, the more water content, C.U., corneometer units )

2. skin elasticity [subjects drank 50 ml every night for 28 days]

   using cutometer dual MPA580 to examine skin elasticity (The closer the R2 value is to 1, the better the elasticity and no unit)

3. skin gloss [subjects drank 50 ml every night for 28 days]

   using probe system GL2000 & MPA10 to examine skin gloss (The higher the value, the higher the gloss, no unit)

4. skin spot [subjects drank 50 ml every night for 28 days]

   usig VISIA-CR to examine skin spot (The higher the value, the larger the pore area, mm2)

5. skin wrinkle [subjects drank 50 ml every night for 28 days]

   using VISIOSCAN-VC20 to examine skin wrinkle (The higher the value, the more wrinkles, surface evaluation of wrinkles, SEW)

6. skin roughness [subjects drank 50 ml every night for 28 days]

   using VISIOSCAN-VC98 to examine skin roughness (The higher the value, the higher the roughness, surface evaluation of roughness, SEr)

7. skin smoothness [subjects drank 50 ml every night for 28 days]

   using VISIOSCAN-VC98 to examine skin smoothness (The lower the value, the higher the smoothness, surface evaluation of smoothness, SEsm)

Eligibility Criteria

Criteria

• Ages Eligible for Study: 20 Years to 65 Years
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: Yes

Inclusion Criteria:

1. Dry skin

2. Rough skin

3. Large pores

4. Dark yellow complexion

5. Sagging skin

Exclusion Criteria:

1. Skin disorders

2. Liver diseases

3. Kidney diseases

4. Allergy to cosmetics, drugs, or foods

5. Pregnant and lactating women

6. People who had any cosmetic procedures before 4 weeks of the study

7. Area of facial spot over 3 cm2

8. Vegan

9. People who took collagen supplements in the past 3 months.

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Research & Design Center, TCI CO., Ltd	Taipei		Taiwan

Sponsors and Collaborators

• TCI Co., Ltd.

Investigators

• Principal Investigator: Chi Fu Chiang, Ph.D, Research & Design Center, TCI CO., Ltd

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: TCI Co., Ltd.
• ClinicalTrials.gov Identifier: NCT04709588
• Other Study ID Numbers: EWISH-20190917-01
• First Posted: Jan 14, 2021
• Last Update Posted: Jan 14, 2021
• Last Verified: Jan 1, 2021

• Individual Participant Data (IPD) Sharing Statement: No
• Plan to Share IPD: No
• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No
• Additional relevant MeSH terms: Skin Diseases; Disease

Study Results

No Results Posted as of Jan 14, 2021