The Effects of Sleep Deprivation on Physiological and Perceptual Responses During Exercise

• Sponsor: St Mary's University College (Other)
• Overall Status: Not yet recruiting
• CT.gov ID: NCT05313932
• Collaborator: (none)
• Enrollment: 12
• Arms: 2
• Anticipated Duration (Months): 5.2

Study Details

Study Description

Brief Summary

Sleep deprivation has been found to impact exercise performance. The effects of both partial (several hours) and full (24+ hours) sleep deprivation on exercise performance has shown effects on rating of perceived exertion, rate of oxygen consumption, respiratory exchange ratio, and heart rate. A common practice with athletes is to perform regular physiological testing (submaximal and maximal) in order to assess their fitness and to determine training intensities. However, the effects of sleep deprivation on those same physiological test results has not been investigated Therefore, the purpose of this study is to investigate the effects of partial sleep deprivation on physiological test results.

Condition or Disease	Intervention/Treatment	Phase
Sleep Deprivation	Other: Sleep deprivation	N/A

Study Design

• Study Type: Interventional
• Anticipated Enrollment: 12 participants
• Allocation: Randomized
• Intervention Model: Crossover Assignment
• Masking: None (Open Label)
• Primary Purpose: Basic Science
• Official Title: The Effects of Partial Sleep Restriction on Physiological and Perceptual Responses During Submaximal and Maximal Exercise in Trained Runners
• Anticipated Study Start Date: Apr 20, 2022
• Anticipated Primary Completion Date: Aug 31, 2022
• Anticipated Study Completion Date: Sep 26, 2022

Arms and Interventions

Arm	Intervention/Treatment
Experimental: Sleep deprivation Two hours of sleep deprivation (Six hours of sleep)	Other: Sleep deprivation; Participants wake after six hours so that they are deprived of 2 hours of sleep
No Intervention: No intervention No sleep deprivation (Eight hours of sleep)

Outcome Measures

Primary Outcome Measures

1. Oxygen uptake [From baseline to completion, up to 31 days]

   Change from baseline in oxygen uptake measured breath-by-breath using an online gas analyzer during submaximal and maximal incremental exercise

2. Respiratory exchange ratio [From baseline to completion, up to 31 days]

   Change from baseline in respiratory exchange ratio measured breath-by-breath using an online gas analyzer during submaximal and maximal incremental exercise

3. Breathing frequency [From baseline to completion, up to 31 days]

   Change from baseline in breathing frequency measured breath-by-breath using an online gas analyzer during submaximal and maximal incremental exercise

4. Minute ventilation [From baseline to completion, up to 31 days]

   Change from baseline in minute ventilation measured breath-by-breath using an online gas analyzer during submaximal and maximal incremental exercise

5. Blood lactate concentration [From baseline to completion, up to 31 days]

   Change from baseline in blood lactate concentration measured using capillary puncture during submaximal and maximal incremental exercise

6. Rating of perceived exertion [From baseline to completion, up to 31 days]

   Change from baseline in ratings of perceived exertion measured using a 15-point (6-20) scale during submaximal and maximal incremental exercise

7. Heart rate [From baseline to completion, up to 31 days]

   Change from baseline in heart rate measured using a heart rate monitor during submaximal and maximal incremental exercise

Eligibility Criteria

Criteria

• Ages Eligible for Study: 18 Years to 45 Years
• Sexes Eligible for Study: Male
• Accepts Healthy Volunteers: Yes

Inclusion Criteria:

• Injury-free, trained, male runners

Exclusion Criteria:

• Female, untrained, injured

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

• St Mary's University College

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: St Mary's University College
• ClinicalTrials.gov Identifier: NCT05313932
• Other Study ID Numbers: StMarysUC4
• First Posted: Apr 6, 2022
• Last Update Posted: Apr 6, 2022
• Last Verified: Mar 1, 2022

• Individual Participant Data (IPD) Sharing Statement: No
• Plan to Share IPD: No
• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No
• Additional relevant MeSH terms: Sleep Deprivation

Study Results

No Results Posted as of Apr 6, 2022