Effects of Sleep Duration on Eating and Activity Behaviors

Sponsor

The Miriam Hospital (Other)

Overall Status

Completed

CT.gov ID

NCT01030107

Collaborator

American Diabetes Association (Other)

Enrollment

Location

Duration (Months)

1.1

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The purpose of the proposed study is to determine whether the amount children sleep is associated with changes in hormones, hunger, motivation to eat, and food intake. Fifty children 8-11 years old who sleep 9-10 hours per night will be enrolled for a 3-week study. For 1 week each, children will be asked to sleep their typical amount, increase their sleep by 1-½ hours, and decrease their sleep by 1-½ hours. Half of the children will be asked to increase their sleep first and half to decrease their sleep first. During each week, the following will be gathered: sleep duration (measured by actigraphy, which is a small device that measures sleep), levels of hormones measured through blood draws, self-reported hunger and appetite, food intake (measured by 3 days of 24-hour recall), how motivated children are to eat (measured using a computer activity), and child height and weight. We believe that when children sleep less they will show changes in hormones associated with hunger and appetite, report being hungrier, be more motivated to eat, and eat more food.

Condition or Disease	Intervention/Treatment	Phase
Sleep Obesity	Behavioral: Increase Sleep Behavioral: Decrease Sleep

Study Design

Study Type:

Observational

Actual Enrollment :

37 participants

Observational Model:

Case-Only

Time Perspective:

Prospective

Official Title:

Sleep Duration and Pediatric Overweight: the Role of Eating Behaviors

Study Start Date :

Feb 1, 2009

Actual Primary Completion Date :

Jan 1, 2012

Actual Study Completion Date :

Jan 1, 2012

Arms and Interventions

Arm	Intervention/Treatment
Children with Insufficient Sleep Children who sleep approximately 9-10 hours/night	Behavioral: Increase Sleep Children are asked to increase their sleep by approximately 1 1/2 hours/night for 1 week. Behavioral: Decrease Sleep Children are asked to decrease their sleep by approximately 1 1/2 hours/night.

Arm

Intervention/Treatment

Children with Insufficient Sleep

Children who sleep approximately 9-10 hours/night

Behavioral: Increase Sleep

Children are asked to increase their sleep by approximately 1 1/2 hours/night for 1 week.

Behavioral: Decrease Sleep

Children are asked to decrease their sleep by approximately 1 1/2 hours/night.

Outcome Measures

Primary Outcome Measures

absolute reinforcing value of food as compared to sedentary activities [after 1 week of typical sleep duration, after 1 week of decreased sleep duration, after 1 week of increased sleep duration]

Secondary Outcome Measures

plasma levels of leptin and ghrelin [after 1 week of typical sleep duration, after 1 week of decreased sleep duration, after 1 week of increased sleep duration]
caloric intake [after 1 week of typical sleep duration, after 1 week of decreased sleep duration, after 1 week of increased sleep duration]
levels of physical activity [after 1 week of typical sleep duration, after 1 week of decreased sleep duration, after 1 week of increased sleep duration]
subjective ratings of hunger and appetite [after 1 week of typical sleep duration, after 1 week of decreased sleep duration, after 1 week of increased sleep duration]

Eligibility Criteria

Criteria

Ages Eligible for Study:

8 Years to 11 Years

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Yes

Inclusion Criteria:

Age 8-11 years old
BMI for age and gender > 5th percentile (but no greater than 100% overweight)
Sleep approximately 9-10 hours nightly
Attend elementary school
Like at least 1 food and 1 activity used in the reinforcement paradigm
Able to understand and complete the reinforcement paradigm

Exclusion Criteria:

Existence of a diagnosable sleep disorder
Medical or psychiatric condition that could influence sleep or weight
Onset of menarche
Inability to complete study materials, including diagnosed disabilities
Dietary restrictions/allergies to foods used in the study that preclude them from study participation