Smoking: Cytokines in Vitreous and Aqueous Humor
Sponsor
Medical University of Graz (Other)
Overall Status
Completed
CT.gov ID
NCT04178499
Collaborator
(none)
50
89
Study Details
Study Description
Brief Summary
Smoking is a risk factor for ophthalmologic diseases. Inflammation might play a role in their pathogenesis.
This study elucidates intraocular cytokine profiles in smokers and non smokers.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Study Design
Study Type:
Observational
Actual Enrollment
:
50 participants
Observational Model:
Ecologic or Community
Time Perspective:
Cross-Sectional
Official Title:
Smoking: Cytokines in Vitreous and Aqueous Humor
Actual Study Start Date
:
Jan 1, 2012
Actual Primary Completion Date
:
Jan 1, 2015
Actual Study Completion Date
:
Jun 1, 2019
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| smokers active smokers |
Diagnostic Test: cytokine analysis
analysis of intraocular cytokines
|
| non-smokers never smokers |
Diagnostic Test: cytokine analysis
analysis of intraocular cytokines
|
Outcome Measures
Primary Outcome Measures
- cotinine [At the time of vitrectomy procedure]
Concentration of intraocular cotinine
Eligibility Criteria
Criteria
Ages Eligible for Study:
18 Years
and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
-
scheduled vitrectomy and/or cataract surgery
-
signed informed consent
Exclusion Criteria:
-
diabetes
-
uveitis
-
rheumatologic disease
-
anti-inflammatory/immunomodulatory medications
-
st.p. intravitreal injections
-
st.p. glaucoma surgery
-
cataract surgery on the eye to be examined within the past 6 months
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- Medical University of Graz
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
Medical University of Graz
ClinicalTrials.gov Identifier:
NCT04178499
Other Study ID Numbers:
- 30-107 ex 17/18
First Posted:
Nov 26, 2019
Last Update Posted:
Nov 26, 2019
Last Verified:
Nov 1, 2019
Individual Participant Data (IPD) Sharing Statement:
No
Plan to Share IPD:
No
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No