Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma
Study Details
Study Description
Brief Summary
This phase III trial studies how well lenalidomide and dexamethasone works with or without daratumumab in treating patients with high-risk smoldering myeloma. Drugs used in chemotherapy, such as lenalidomide and dexamethasone, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Immunotherapy with monoclonal antibodies, such as daratumumab, may induce changes in the body's immune system and may interfere with the ability of tumor cells to grow and spread. Giving lenalidomide and dexamethasone with daratumumab may work better in treating patients with smoldering myeloma.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Phase 3 |
Detailed Description
PRIMARY OBJECTIVES:
- To compare overall survival in patients with high-risk smoldering multiple myeloma randomized to daratumumab-lenalidomide (revlimid)-dexamethasone or revlimid-dexamethasone.
SECONDARY OBJECTIVES:
-
To compare progression-free survival and response rates between arms. II. To evaluate safety and compare toxicity rates between arms. III. To monitor incidence of infusion-related reactions over the first cycle of daratumumab.
-
To evaluate stem cell mobilization failure and early stem cell mobilization feasibility.
EXPLORATORY OBJECTIVES:
- To measure treatment exposure and adherence. II. To estimate treatment duration and time to progression.
PATIENT-REPORTED OUTCOMES OBJECTIVES:
-
To compare change in health-related quality of life (Functional Assessment of Cancer Therapy [FACT]- General [G]]) from baseline to end of study therapy between arms.
-
To compare change in FACT-G scores from treatment end to 6-months post-treatment end between arms.
-
To describe changes in FACT-G scores over study therapy and shortly after treatment discontinuation and evaluate correlation with survival.
-
To evaluate attributes of select patient reported treatment-emergent symptomatic adverse events (Patient Reported Outcomes [PRO]-Common Terminology Criteria for Adverse Events [CTCAE]) longitudinally.
-
To derive an overall PRO-CTCAE score at each assessment time point. VI. To measure the likelihood of medication adherence (ASK-12) at 6 month intervals throughout treatment.
-
To assess the association of overall PRO-CTCAE score with FACT-G score. VIII. To compare select PRO-CTCAE items and related provider-reported CTCAEs. IX. To evaluate association between treatment adherence and Adherence Starts with Knowledge 12 (ASK-12) score.
-
To assess correlation of treatment adherence and ASK-12 score with FACT-G score.
-
To tabulate PRO compliance and completion rates.
LABORATORY OBJECTIVES:
-
To compare minimal residual disease negative rate after 12 cycles of study therapy between arms.
-
To compare minimal residual disease (MRD) positive to negative conversion rates from 12 cycles to end of treatment between arms.
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To examine patterns of change in minimal residual disease levels during study therapy.
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To evaluate agreement and discordance between methods determining disease-free status.
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To assess the prognostic value of minimal residual disease status at 12 cycles for overall and progression-free survival.
IMAGING OBJECTIVES:
-
To evaluate the association of baseline fludeoxyglucose F-18 (FDG)-positron emission tomography (PET)/computed tomography (CT) imaging with progression-free survival.
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To assess the ability of baseline FDG-PET/CT to predict minimal residual disease status after 12 cycles of study therapy and at the end of study therapy.
-
To describe the results of subsequent FDG-PET/CT imaging studies in the subset of patients with baseline abnormal FDG-PET/CT, and to associate these results with progression-free survival (PFS).
OUTLINE: Patients are randomized to 1 of 2 arms.
ARM I: Patients receive daratumumab intravenously (IV) on days 1, 8, 15, and 22 of courses 1-2, days 1 and 15 of courses 3-6, and day 1 of courses 7-24. Patients also receive lenalidomide orally (PO) daily on days 1-21 and dexamethasone PO on days 1, 8, 15, and 22 in courses 1-12. Treatment repeats every 28 days for up to 24 courses in the absence of disease progression or unacceptable toxicity.
ARM II: Patients receive lenalidomide PO daily on days 1-21 and dexamethasone PO on days 1, 8, 15, and 22 of courses 1-12. Treatment repeats every 28 days for up to 24 courses in the absence of disease progression or unacceptable toxicity.
After completion of study, patients will be followed up every 3, 6 or 12 months for up to 15 years from study entry.
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Experimental: Arm I (daratumumab, lenalidomide, dexamethasone) Patients receive daratumumab IV on days 1, 8, 15, and 22 of courses 1-2, days 1 and 15 of courses 3-6, and day 1 of courses 7-24. Patients also receive lenalidomide PO daily on days 1-21 and dexamethasone PO on days 1, 8, 15, and 22 in courses 1-12. Treatment repeats every 28 days for up to 24 courses in the absence of disease progression or unacceptable toxicity. |
Biological: Daratumumab
Given IV
Other Names:
Drug: Dexamethasone
Given PO
Other Names:
Drug: Lenalidomide
Given PO
Other Names:
Other: Questionnaire Administration
Ancillary studies
|
| Experimental: Arm II (lenalidomide, dexamethasone) Patients receive lenalidomide PO daily on days 1-21 and dexamethasone PO on days 1, 8, 15, and 22 of courses 1-12. Treatment repeats every 28 days for up to 24 courses in the absence of disease progression or unacceptable toxicity. |
Drug: Dexamethasone
Given PO
Other Names:
Drug: Lenalidomide
Given PO
Other Names:
Other: Quality-of-Life Assessment
Ancillary studies
Other Names:
Other: Questionnaire Administration
Ancillary studies
|
Outcome Measures
Primary Outcome Measures
- Overall survival (OS) [From randomization to death due to any cause, or censored at date last known alive, assessed up to 15 years]
Will be estimated using the Kaplan-Meier (KM) method and compared using a stratified log-rank test. Stratified cox proportional hazards regression will produce a treatment hazard ratio estimate.
- Functional Assessment of Cancer Therapy-General (FACT-G) score [Baseline to 24 cycles of treatment (each cycle is 28 days)]
A general effect size measure of half standard deviation will be used to establish the minimally important difference. Descriptive statistics (mean, standard deviation [SD], median, range) will be used to evaluate the distribution of levels and changes for the set of health-related quality of life (QOL) evaluations. Levels and changes will also be assessed graphically. Changes from baseline will be analyzed using linear mixed models based on restricted maximum likelihood estimation with covariance matrix maximizing Akaike information criteria. Models with treatment, assessment time, and treatment by assessment time interaction with and without other predictors will be fit. If there is substantial missingness, will analyze the data according to the methods described in Schluchter and Schluchter, Greene and Beck.
Secondary Outcome Measures
- Progression-free survival (PFS) [From randomization until disease progression or death due to any cause, or censored at date of last disease evaluation, assessed up to 15 years]
Will be estimated using the KM method and compared using a stratified log-rank test. Stratified cox proportional hazards regression will produce a treatment hazard ratio estimate.
- Best response on treatment based on International Myeloma Working Group (IMWG) criteria [At 12 and 24 months]
Response will be tabulated by category. Response rates of very good partial response (VGPR) or better and partial response (PR) or better will be compared using the Fisher's exact test. Ineligible patients are excluded from the analysis and unevaluable patients are counted in the denominator.
- Incidence of adverse events by worst grade and type for treated patients determined using Common Terminology Criteria for Adverse Events (CTCAE) version 5.0 [Up to 28 days post-treatment]
Will monitor the toxicities experienced by all treated patients. Will compare rates of worst grade 3 or higher non-hematologic treatment-related events using the Fisher's exact test.
- Incidence of grade 3 or higher infusion-related reactions over course 1 determined based on CTCAE [During cycle 1 of treatment (each cycle is 28 days)]
Will monitor the toxicities experienced by all treated patients. Will compare rates of worst grade 3 or higher non-hematologic treatment-related events using the Fisher's exact test.
- Stem cell (SC) mobilization failure [After 4 to 6 cycles of treatment (each cycle is 28 days)]
Defined as not collecting a minimum of 5x10^6 CD34 cells per kilogram weight. SC mobilization and type of growth factor support will be summarized overall and by treatment arm with descriptive statistics.
- Early SC mobilization feasibility [Up to 6 cycles of treatment (each cycle is 28 days)]
Defined as the proportion of patients less than 65 years of age treated for 6 courses who opt for SC mobilization. SC mobilization and type of growth factor support will be summarized overall and by treatment arm with descriptive statistics.
- Type of growth factor support [During 4 to 6 cycles of treatment (each cycle is 28 days)]
SC mobilization and type of growth factor support will be summarized overall and by treatment arm with descriptive statistics.
- Change in FACT-G score [From treatment end to 6 months post-treatment]
A general effect size measure of half standard deviation will be used to establish the minimally important difference. Descriptive statistics (mean, SD, median, range) will be used to evaluate the distribution of levels and changes for the set of health-related QOL evaluations. Levels and changes will also be assessed graphically. Changes from baseline will be analyzed using linear mixed models based on restricted maximum likelihood estimation with covariance matrix maximizing Akaike information criteria. Models with treatment, assessment time, and treatment by assessment time interaction with and without other predictors will be fit. If there is substantial missingness, will analyze the data according to the methods described in Schluchter and Schluchter, Greene and Beck.
- Levels of FACT-G score at each assessment time point [From baseline, at 3, f7, 13, 19 cycles of treatment, and early discontinuation of treatment, assessed up to 24 cycles of treatment (each cycle is 28 days)]
A general effect size measure of half standard deviation will be used to establish the minimally important difference. Descriptive statistics (mean, SD, median, range) will be used to evaluate the distribution of levels and changes for the set of health-related QOL evaluations. Levels and changes will also be assessed graphically. Changes from baseline will be analyzed using linear mixed models based on restricted maximum likelihood estimation with covariance matrix maximizing Akaike information criteria. Models with treatment, assessment time, and treatment by assessment time interaction with and without other predictors will be fit. If there is substantial missingness, will analyze the data according to the methods described in Schluchter and Schluchter, Greene and Beck.
- Time to worsening of FACT-G [From baseline until a decrease of 9 points, or censored at date of last assessment, assessed up to 6 months post-treatment]
Will be analyzed with Kaplan-Meier methods and Cox regression with the related treatment arm as the only factor. Correlation between time to worsening of symptoms with PFS and OS will be assessed with Kendall's Tau adjusted for censored observations.
Other Outcome Measures
- Cumulative dose calculated as the sum of all doses taken across all cycles [Up to 24 months]
Cumulative dose will be calculated overall and by cycle. Data will be summarized by treatment arm with descriptive statistics and graphically over time. Patients will be classified into dichotomous groups based on a 75% relative dose intensity cutoff (< 75% versus [vs] >= 75% represents poor vs good treatment adherence). The proportion of patients with poor lenalidomide treatment adherence will be compared between arms using the Fisher's exact test. In addition, multi-variable logistic regression analysis will be conducted to identify the baseline factors associated with calculated good treatment adherence.
- Dose intensity calculated as cumulative dose received divided by treatment duration [Up to 24 months]
Dose intensity will be calculated overall and by cycle. Data will be summarized by treatment arm with descriptive statistics and graphically over time. Patients will be classified into dichotomous groups based on a 75% relative dose intensity cutoff (< 75% vs >= 75% represents poor vs good treatment adherence). The proportion of patients with poor lenalidomide treatment adherence will be compared between arms using the Fisher's exact test. In addition, multi-variable logistic regression analysis will be conducted to identify the baseline factors associated with calculated good treatment adherence.
- Relative dose intensity calculated as the dose intensity divided by planned dose intensity [Up to 24 months]
Dose intensity will be calculated overall and by cycle. Data will be summarized by treatment arm with descriptive statistics and graphically over time. Patients will be classified into dichotomous groups based on a 75% relative dose intensity cutoff (< 75% vs >= 75% represents poor vs good treatment adherence). The proportion of patients with poor lenalidomide treatment adherence will be compared between arms using the Fisher's exact test. In addition, multi-variable logistic regression analysis will be conducted to identify the baseline factors associated with calculated good treatment adherence.
- Duration of treatment [From randomization to date off treatment, or censored at the date of last treatment, assessed up to 24 months]
Treatment duration in each arm will be estimated using Kaplan-Meier methods and compared between arms with the log-rank test.
- Time to progression [From randomization to progression, or censored at date of last disease evaluation, assessed up to 15 years]
Will be estimated using the Kaplan-Meier method.
- Presence, frequency, interference, amount and/or severity of select patient reported outcomes (PRO)-CTCAEs [Assessed at each treatment cycle, from cycle 1 of treatment to end of treatment, up to 24 cycles of treatment (each cycle is 28 days)]
Descriptive statistics (mean, standard deviation, median, range) will be used to summarize selected PRO-CTCAEs tabulated at each cycle overall and by arm. Will map PRO-CTCAEs with provider reported adverse events (AEs) and evaluate differences in incidence and worst severity. Items correspond to 5 attributes measured [frequency (F), severity (S), interference (I), presence/absence (P) and amount (A)] based on multiple choice questions. Response for each attribute except P which is binary is on a 5-point Likert scale with 5 indicating 'almost constantly' frequency, 'very severe' severity, 'very much' amount or 'very much' interference. An overall PRO-CTCAE score will be calculated at each time point.
- Overall PRO-CTCAE score [Up to 15 years]
Defined as the sum of item scores on all symptomatic adverse events (AEs). Descriptive statistics will be used to summarize selected PRO-CTCAEs tabulated at each cycle overall and by arm. Will map PRO-CTCAEs with provider reported AEs and evaluate differences in incidence and worst severity. An overall PRO-CTCAE score will be calculated at each time point.
- Adherence Starts with Knowledge (ASK)-12 scores [At 7, 13, and 19 cycles of treatment (each cycle is 28 days)]
Descriptive statistics will be used to summarize ASK-12 scores tabulated at cycles 7, 13 and 19 overall and by arm. Differences between arms will be evaluated based a t-test (or Wilcoxon rank sum test). Patients will also be classified into high versus low likelihood of medication adherence groups according to tertile distributions (lowest tertile vs second and top). Association between likelihood of medication adherence and calculated treatment adherence dichotomous groups will be evaluated in patients with both ASK-12 and treatment data at cycles 7, 13 and 19 post randomization. In addition, multivariable logistic regression analysis will be conducted to identify the baseline factors associated with low likelihood of medication adherence.
- PRO compliance rate [Up to 15 years]
Defined as the proportion of patients who submit the given PRO instrument among those eligible at each time point which excludes those missing by design (due to death or disease progression, early treatment discontinuation).
- PRO completion rate [Up to 15 years]
Defined as the proportion of patients who complete given PRO instrument based on the instrument's scoring system among those eligible at each time point.
Eligibility Criteria
Criteria
Inclusion Criteria:
-
Patients must be diagnosed with asymptomatic high-risk smoldering multiple myeloma (SMM) within the past 12 months. High-risk is defined by the presence of 2 or more of the following factors:
-
Abnormal serum free light chain ratio of involved to uninvolved >20, but less than 100 if the involved FLC is >= 10 mg/dL by serum free light chain (FLC) assay
-
Serum M-protein level >= 2 gm/dL
-
Presence of t(4;14) or del 17p, del 13q or 1q gain by conventional cytogenetics or fluorescence in situ hybridization (FISH) studies.
-
20% plasma cells on biopsy or aspirate
-
Bone marrow aspirate and/or biopsy is required to be performed within 42 days prior to randomization and must demonstrate 10-59% clonal plasma cells.
-
= 1 g/dL on serum protein electrophoresis (within 28 days prior to randomization).
-
= 200 mg of monoclonal protein on a 24 hour urine protein electrophoresis (within 28 days prior to randomization).
-
NOTE: In the rare situation where the serum protein electrophoresis (SPEP) is felt to be unreliable, then quantitative immunoglobulin levels on nephelometry or turbidometry can be accepted.
-
SPEP, urine protein electrophoresis (UPEP), and serum FLC are required to be performed within 28 days prior to randomization.
-
NOTE: UPEP (on a 24-hour collection) is required; no substitute method is acceptable. Urine must be followed monthly if the baseline urine M-spike is >= 200 mg/24 hour (hr), and urine in addition to serum must be followed in order to confirm a very good partial response (VGPR) or higher response.
-
Patients must have no lytic lesions, no known plasmacytoma, and no unexplained hypercalcemia (i.e., > 11 mg/dL or 1mg/dL above upper limit of normal [ULN]).
-
Hemoglobin >= 11 g/dL (within 28 days prior to randomization).
-
Platelet count >= 100,000 cells/mm^3 (within 28 days prior to randomization).
-
Absolute neutrophil count >= 1500 cells/mm^3 (within 28 days prior to randomization).
-
Calculated creatinine clearance >= 30 mL/min (within 28 days prior to randomization).
-
Bilirubin =< 1.5 mg/dL (within 28 days prior to randomization).
-
Serum glutamate pyruvate transaminase (SGPT) (alanine aminotransferase [ALT]) and serum glutamic oxaloacetic transaminase (SGOT) (aspartate aminotransferase [AST]) =< 2.5 times the upper limit of normal (within 28 days prior to randomization).
-
Patients must not have any prior or concurrent systemic or radiation therapy for the treatment of myeloma. Patients must also not have contraindication to deep vein thrombosis (DVT) prophylaxis/aspirin.
-
Patients must not have more than one focal marrow lesion on magnetic resonance imaging (MRI) of either pelvis or spine. Patients with indwelling pacemakers and/or ICD (implantable cardioverter-defibrillator) that is known or suspected to be MRI incompatible will be excused from this test.
-
Concurrent use of erythropoietin is not allowed while on study therapy.
-
Prior or glucocorticosteroid therapy for the treatment of multiple myeloma is not permitted. Prior systemic glucocorticosteroid use for the treatment of non-malignant disorders is permitted; concurrent use after registration on the study should be restricted to the equivalent of prednisone 10 mg per day. Prior or concurrent topical or localized glucocorticosteroid therapy to treat non-malignant comorbid disorders is permitted.
-
Patients must not have active, uncontrolled seizure disorder. Patients must not have had a seizure in the last 6 months.
-
Patients must not have uncontrolled intercurrent illness including uncontrolled hypertension, symptomatic congestive heart failure, unstable angina, uncontrolled cardiac arrhythmia, uncontrolled psychiatric illness or social situation that would limit compliance with the study, or a prior history of Stevens Johnson syndrome.
-
Patient must have an Eastern Cooperative Oncology Group (ECOG) performance status 0, 1, or 2.
-
Patients with monoclonal gammopathy of undetermined significance are not eligible.
-
Patients must not have grade 2 or higher peripheral neuropathy per CTCAE.
-
Patients must not have active, uncontrolled infection.
-
Patients may have a history of current or previous deep vein thrombosis or pulmonary embolism but are required to take some form of anti-coagulation as prophylaxis if they are not currently on full-dose anticoagulation.
-
Patients should not have New York Heart Association classification III or IV heart failure at baseline.
-
Patients with a history of prior malignancy are eligible provided they were treated with curative intent and have been free of disease for the time period considered appropriate for cure of the specific cancer. For most diseases this time frame is 5 years.
-
Patients must agree to register into the mandatory Risk Evaluation and Mitigation Strategy (REMS) program and be willing and able to comply with the requirements of REMS.
-
Women must not be pregnant due to potential harm to the fetus from daratumumab and lenalidomide. All females of childbearing potential (FCBP) must have a blood test or urine study with a sensitivity of at least 25 mIU/mL within 10-14 days prior to the first dose of lenalidomide and again within 24 hours prior to the first dose of lenalidomide. FCBP must also agree to ongoing pregnancy testing while on treatment. A female of childbearing potential is any woman, regardless of sexual orientation or whether they have undergone tubal ligation, who meets the following criteria: 1) has achieved menarche at some point, 2) has not undergone a hysterectomy or bilateral oophorectomy, or 3) has not been naturally postmenopausal (amenorrhea following cancer therapy does not rule out childbearing potential) for at least 24 consecutive months (i.e., has had menses at any time in the preceding 24 consecutive months).
-
Females of childbearing potential (FCBP) must either abstain from sexual intercourse for the duration of their participation in the study or agree to use TWO acceptable methods of birth control, one highly effective method and one additional effective method AT THE SAME TIME for 1) at least 28 days before starting study treatment; 2) while participating in the study; 3) during dose interruptions; and 4) for at least 28 days after the last dose of protocol treatment (FCBP who are assigned to Arm A and receive daratumumab must extend this contraception requirement to 3 months after the last dose of protocol treatment). Women must also agree to not breastfeed during this same time period. Men must agree to either abstain from sexual intercourse for the duration of their participation in the study or use a latex condom during sexual contact with a FCBP while participating in the study and for 28 days after the last dose of protocol treatment even if they have had a successful vasectomy. Men must also agree to abstain from donating sperm while on study treatment and for 28 days after the last dose of protocol treatment even if they have had a successful vasectomy. Both women and men must both agree to abstain from donating blood during study participation and for at least 28 days after the last dose of protocol treatment.
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Human immunodeficiency virus (HIV)+ patients with undetectable HIV viral loads tested within 6 months are eligible.
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Patients should not have a history of allergic reactions attributed to compounds of similar chemical or biologic composition to daratumumab, lenalidomide, or dexamethasone.
-
Patients must not have known chronic obstructive pulmonary disease (COPD) with a forced expiratory volume in 1 second (FEV1) <50% of predicted normal or known moderate or severe persistent asthma within 2 years prior to randomization
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Anchorage Associates in Radiation Medicine | Anchorage | Alaska | United States | 98508 |
| 2 | Anchorage Radiation Therapy Center | Anchorage | Alaska | United States | 99504 |
| 3 | Alaska Breast Care and Surgery LLC | Anchorage | Alaska | United States | 99508 |
| 4 | Alaska Oncology and Hematology LLC | Anchorage | Alaska | United States | 99508 |
| 5 | Alaska Women's Cancer Care | Anchorage | Alaska | United States | 99508 |
| 6 | Anchorage Oncology Centre | Anchorage | Alaska | United States | 99508 |
| 7 | Katmai Oncology Group | Anchorage | Alaska | United States | 99508 |
| 8 | Providence Alaska Medical Center | Anchorage | Alaska | United States | 99508 |
| 9 | Fairbanks Memorial Hospital | Fairbanks | Alaska | United States | 99701 |
| 10 | CTCA at Western Regional Medical Center | Goodyear | Arizona | United States | 85338 |
| 11 | Kingman Regional Medical Center | Kingman | Arizona | United States | 86401 |
| 12 | Cancer Center at Saint Joseph's | Phoenix | Arizona | United States | 85004 |
| 13 | Mayo Clinic Hospital in Arizona | Phoenix | Arizona | United States | 85054 |
| 14 | Mayo Clinic in Arizona | Scottsdale | Arizona | United States | 85259 |
| 15 | Mercy Hospital Fort Smith | Fort Smith | Arkansas | United States | 72903 |
| 16 | CHI Saint Vincent Cancer Center Hot Springs | Hot Springs | Arkansas | United States | 71913 |
| 17 | Mission Hope Medical Oncology - Arroyo Grande | Arroyo Grande | California | United States | 93420 |
| 18 | PCR Oncology | Arroyo Grande | California | United States | 93420 |
| 19 | Providence Saint Joseph Medical Center/Disney Family Cancer Center | Burbank | California | United States | 91505 |
| 20 | Epic Care-Dublin | Dublin | California | United States | 94568 |
| 21 | Bay Area Breast Surgeons Inc | Emeryville | California | United States | 94608 |
| 22 | Epic Care Partners in Cancer Care | Emeryville | California | United States | 94608 |
| 23 | UC San Diego Moores Cancer Center | La Jolla | California | United States | 92093 |
| 24 | Contra Costa Regional Medical Center | Martinez | California | United States | 94553-3156 |
| 25 | Alta Bates Summit Medical Center - Summit Campus | Oakland | California | United States | 94609 |
| 26 | Bay Area Tumor Institute | Oakland | California | United States | 94609 |
| 27 | Eisenhower Medical Center | Rancho Mirage | California | United States | 92270 |
| 28 | Pacific Central Coast Health Center-San Luis Obispo | San Luis Obispo | California | United States | 93401 |
| 29 | Mission Hope Medical Oncology - Santa Maria | Santa Maria | California | United States | 93444 |
| 30 | Epic Care Cyberknife Center | Walnut Creek | California | United States | 94597 |
| 31 | Rocky Mountain Cancer Centers-Aurora | Aurora | Colorado | United States | 80012 |
| 32 | The Medical Center of Aurora | Aurora | Colorado | United States | 80012 |
| 33 | Boulder Community Hospital | Boulder | Colorado | United States | 80301 |
| 34 | Rocky Mountain Cancer Centers-Boulder | Boulder | Colorado | United States | 80304 |
| 35 | Rocky Mountain Cancer Centers - Centennial | Centennial | Colorado | United States | 80112 |
| 36 | Penrose-Saint Francis Healthcare | Colorado Springs | Colorado | United States | 80907 |
| 37 | Rocky Mountain Cancer Centers-Penrose | Colorado Springs | Colorado | United States | 80907 |
| 38 | Saint Francis Cancer Center | Colorado Springs | Colorado | United States | 80923 |
| 39 | Cancer Center of Colorado at Sloan's Lake | Denver | Colorado | United States | 80204 |
| 40 | National Jewish Health-Main Campus | Denver | Colorado | United States | 80206 |
| 41 | The Women's Imaging Center | Denver | Colorado | United States | 80209 |
| 42 | Porter Adventist Hospital | Denver | Colorado | United States | 80210 |
| 43 | Colorado Blood Cancer Institute | Denver | Colorado | United States | 80218 |
| 44 | Presbyterian - Saint Lukes Medical Center - Health One | Denver | Colorado | United States | 80218 |
| 45 | Rocky Mountain Cancer Centers-Midtown | Denver | Colorado | United States | 80218 |
| 46 | SCL Health Saint Joseph Hospital | Denver | Colorado | United States | 80218 |
| 47 | Rocky Mountain Cancer Centers-Rose | Denver | Colorado | United States | 80220 |
| 48 | Rose Medical Center | Denver | Colorado | United States | 80220 |
| 49 | Western Surgical Care | Denver | Colorado | United States | 80220 |
| 50 | Mercy Medical Center | Durango | Colorado | United States | 81301 |
| 51 | Southwest Oncology PC | Durango | Colorado | United States | 81301 |
| 52 | Mountain Blue Cancer Care Center - Swedish | Englewood | Colorado | United States | 80113 |
| 53 | Swedish Medical Center | Englewood | Colorado | United States | 80113 |
| 54 | The Melanoma and Skin Cancer Institute | Englewood | Colorado | United States | 80113 |
| 55 | National Jewish Health-Western Hematology Oncology | Golden | Colorado | United States | 80401 |
| 56 | Saint Mary's Hospital and Regional Medical Center | Grand Junction | Colorado | United States | 81501 |
| 57 | North Colorado Medical Center | Greeley | Colorado | United States | 80631 |
| 58 | Good Samaritan Medical Center | Lafayette | Colorado | United States | 80026 |
| 59 | Saint Anthony Hospital | Lakewood | Colorado | United States | 80228 |
| 60 | Rocky Mountain Cancer Centers-Littleton | Littleton | Colorado | United States | 80120 |
| 61 | Littleton Adventist Hospital | Littleton | Colorado | United States | 80122 |
| 62 | Rocky Mountain Cancer Centers-Sky Ridge | Lone Tree | Colorado | United States | 80124 |
| 63 | Sky Ridge Medical Center | Lone Tree | Colorado | United States | 80124 |
| 64 | Longmont United Hospital | Longmont | Colorado | United States | 80501 |
| 65 | Rocky Mountain Cancer Centers-Longmont | Longmont | Colorado | United States | 80501 |
| 66 | McKee Medical Center | Loveland | Colorado | United States | 80539 |
| 67 | Parker Adventist Hospital | Parker | Colorado | United States | 80138 |
| 68 | Saint Mary Corwin Medical Center | Pueblo | Colorado | United States | 81004 |
| 69 | National Jewish Health-Northern Hematology Oncology | Thornton | Colorado | United States | 80260 |
| 70 | Rocky Mountain Cancer Centers-Thornton | Thornton | Colorado | United States | 80260 |
| 71 | SCL Health Lutheran Medical Center | Wheat Ridge | Colorado | United States | 80033 |
| 72 | Smilow Cancer Hospital-Derby Care Center | Derby | Connecticut | United States | 06418 |
| 73 | Smilow Cancer Hospital Care Center-Fairfield | Fairfield | Connecticut | United States | 06824 |
| 74 | Smilow Cancer Hospital Care Center at Glastonbury | Glastonbury | Connecticut | United States | 06033 |
| 75 | Smilow Cancer Hospital Care Center - Guiford | Guilford | Connecticut | United States | 06437 |
| 76 | Smilow Cancer Hospital Care Center at Saint Francis | Hartford | Connecticut | United States | 06105 |
| 77 | Smilow Cancer Center/Yale-New Haven Hospital | New Haven | Connecticut | United States | 06510 |
| 78 | Yale University | New Haven | Connecticut | United States | 06520 |
| 79 | Yale-New Haven Hospital North Haven Medical Center | North Haven | Connecticut | United States | 06473 |
| 80 | Smilow Cancer Hospital-Orange Care Center | Orange | Connecticut | United States | 06477 |
| 81 | Smilow Cancer Hospital-Torrington Care Center | Torrington | Connecticut | United States | 06790 |
| 82 | Smilow Cancer Hospital Care Center-Trumbull | Trumbull | Connecticut | United States | 06611 |
| 83 | Smilow Cancer Hospital-Waterbury Care Center | Waterbury | Connecticut | United States | 06708 |
| 84 | Smilow Cancer Hospital Care Center - Waterford | Waterford | Connecticut | United States | 06385 |
| 85 | Holy Cross Hospital | Fort Lauderdale | Florida | United States | 33308 |
| 86 | Cleveland Clinic-Weston | Weston | Florida | United States | 33331 |
| 87 | Emory University Hospital/Winship Cancer Institute | Atlanta | Georgia | United States | 30322 |
| 88 | Emory Saint Joseph's Hospital | Atlanta | Georgia | United States | 30342 |
| 89 | Lewis Cancer and Research Pavilion at Saint Joseph's/Candler | Savannah | Georgia | United States | 31405 |
| 90 | Saint Alphonsus Cancer Care Center-Boise | Boise | Idaho | United States | 83706 |
| 91 | Saint Luke's Cancer Institute - Boise | Boise | Idaho | United States | 83712 |
| 92 | Saint Alphonsus Cancer Care Center-Caldwell | Caldwell | Idaho | United States | 83605 |
| 93 | Kootenai Health - Coeur d'Alene | Coeur d'Alene | Idaho | United States | 83814 |
| 94 | Walter Knox Memorial Hospital | Emmett | Idaho | United States | 83617 |
| 95 | Saint Luke's Cancer Institute - Fruitland | Fruitland | Idaho | United States | 83619 |
| 96 | Idaho Urologic Institute-Meridian | Meridian | Idaho | United States | 83642 |
| 97 | Saint Luke's Cancer Institute - Meridian | Meridian | Idaho | United States | 83642 |
| 98 | Saint Alphonsus Medical Center-Nampa | Nampa | Idaho | United States | 83686 |
| 99 | Saint Luke's Cancer Institute - Nampa | Nampa | Idaho | United States | 83686 |
| 100 | Kootenai Clinic Cancer Services - Post Falls | Post Falls | Idaho | United States | 83854 |
| 101 | Kootenai Cancer Clinic | Sandpoint | Idaho | United States | 83864 |
| 102 | Saint Luke's Cancer Institute - Twin Falls | Twin Falls | Idaho | United States | 83301 |
| 103 | Rush - Copley Medical Center | Aurora | Illinois | United States | 60504 |
| 104 | Loyola Center for Health at Burr Ridge | Burr Ridge | Illinois | United States | 60527 |
| 105 | Carle on Vermilion | Danville | Illinois | United States | 61832 |
| 106 | Northwestern Medicine Cancer Center Kishwaukee | DeKalb | Illinois | United States | 60115 |
| 107 | Carle Physician Group-Effingham | Effingham | Illinois | United States | 62401 |
| 108 | NorthShore University HealthSystem-Evanston Hospital | Evanston | Illinois | United States | 60201 |
| 109 | Northwestern Medicine Cancer Center Delnor | Geneva | Illinois | United States | 60134 |
| 110 | NorthShore University HealthSystem-Glenbrook Hospital | Glenview | Illinois | United States | 60026 |
| 111 | Ingalls Memorial Hospital | Harvey | Illinois | United States | 60426 |
| 112 | NorthShore University HealthSystem-Highland Park Hospital | Highland Park | Illinois | United States | 60035 |
| 113 | Loyola Medicine Homer Glen | Homer Glen | Illinois | United States | 60491 |
| 114 | Duly Health and Care Joliet | Joliet | Illinois | United States | 60435 |
| 115 | Carle Physician Group-Mattoon/Charleston | Mattoon | Illinois | United States | 61938 |
| 116 | Loyola University Medical Center | Maywood | Illinois | United States | 60153 |
| 117 | Marjorie Weinberg Cancer Center at Loyola-Gottlieb | Melrose Park | Illinois | United States | 60160 |
| 118 | Good Samaritan Regional Health Center | Mount Vernon | Illinois | United States | 62864 |
| 119 | Illinois Cancer Specialists-Niles | Niles | Illinois | United States | 60714 |
| 120 | North Shore Medical Center | Skokie | Illinois | United States | 60076 |
| 121 | Carle Cancer Center | Urbana | Illinois | United States | 61801 |
| 122 | The Carle Foundation Hospital | Urbana | Illinois | United States | 61801 |
| 123 | Northwestern Medicine Cancer Center Warrenville | Warrenville | Illinois | United States | 60555 |
| 124 | Rush-Copley Healthcare Center | Yorkville | Illinois | United States | 60560 |
| 125 | Indiana University/Melvin and Bren Simon Cancer Center | Indianapolis | Indiana | United States | 46202 |
| 126 | Springmill Medical Center | Indianapolis | Indiana | United States | 46290 |
| 127 | Reid Health | Richmond | Indiana | United States | 47374 |
| 128 | Mary Greeley Medical Center | Ames | Iowa | United States | 50010 |
| 129 | McFarland Clinic PC - Ames | Ames | Iowa | United States | 50010 |
| 130 | McFarland Clinic PC-Boone | Boone | Iowa | United States | 50036 |
| 131 | Saint Anthony Regional Hospital | Carroll | Iowa | United States | 51401 |
| 132 | Medical Oncology and Hematology Associates-West Des Moines | Clive | Iowa | United States | 50325 |
| 133 | Mercy Cancer Center-West Lakes | Clive | Iowa | United States | 50325 |
| 134 | Alegent Health Mercy Hospital | Council Bluffs | Iowa | United States | 51503 |
| 135 | Greater Regional Medical Center | Creston | Iowa | United States | 50801 |
| 136 | Iowa Methodist Medical Center | Des Moines | Iowa | United States | 50309 |
| 137 | Medical Oncology and Hematology Associates-Des Moines | Des Moines | Iowa | United States | 50309 |
| 138 | Broadlawns Medical Center | Des Moines | Iowa | United States | 50314 |
| 139 | Medical Oncology and Hematology Associates-Laurel | Des Moines | Iowa | United States | 50314 |
| 140 | Mercy Medical Center - Des Moines | Des Moines | Iowa | United States | 50314 |
| 141 | Iowa Lutheran Hospital | Des Moines | Iowa | United States | 50316 |
| 142 | McFarland Clinic PC-Trinity Cancer Center | Fort Dodge | Iowa | United States | 50501 |
| 143 | Trinity Regional Medical Center | Fort Dodge | Iowa | United States | 50501 |
| 144 | McFarland Clinic PC-Jefferson | Jefferson | Iowa | United States | 50129 |
| 145 | McFarland Clinic PC-Marshalltown | Marshalltown | Iowa | United States | 50158 |
| 146 | Methodist West Hospital | West Des Moines | Iowa | United States | 50266-7700 |
| 147 | Mercy Medical Center-West Lakes | West Des Moines | Iowa | United States | 50266 |
| 148 | Central Care Cancer Center - Garden City | Garden City | Kansas | United States | 67846 |
| 149 | Central Care Cancer Center - Great Bend | Great Bend | Kansas | United States | 67530 |
| 150 | Saint Luke's South Hospital | Overland Park | Kansas | United States | 66213 |
| 151 | Cotton O'Neil Cancer Center / Stormont Vail Health | Topeka | Kansas | United States | 66606 |
| 152 | Flaget Memorial Hospital | Bardstown | Kentucky | United States | 40004 |
| 153 | Commonwealth Cancer Center-Corbin | Corbin | Kentucky | United States | 40701 |
| 154 | Saint Joseph Radiation Oncology Resource Center | Lexington | Kentucky | United States | 40504 |
| 155 | Saint Joseph Hospital East | Lexington | Kentucky | United States | 40509 |
| 156 | Saint Joseph London | London | Kentucky | United States | 40741 |
| 157 | Jewish Hospital | Louisville | Kentucky | United States | 40202 |
| 158 | The James Graham Brown Cancer Center at University of Louisville | Louisville | Kentucky | United States | 40202 |
| 159 | Saints Mary and Elizabeth Hospital | Louisville | Kentucky | United States | 40215 |
| 160 | Jewish Hospital Medical Center Northeast | Louisville | Kentucky | United States | 40245 |
| 161 | Jewish Hospital Medical Center South | Shepherdsville | Kentucky | United States | 40165 |
| 162 | Hematology/Oncology Clinic PLLC | Baton Rouge | Louisiana | United States | 70809 |
| 163 | Ochsner LSU Health Monroe Medical Center | Monroe | Louisiana | United States | 71202 |
| 164 | Tulane University Health Sciences Center | New Orleans | Louisiana | United States | 70112 |
| 165 | Ochsner Medical Center Jefferson | New Orleans | Louisiana | United States | 70121 |
| 166 | LSU Health Sciences Center at Shreveport | Shreveport | Louisiana | United States | 71103 |
| 167 | Saint Agnes Hospital | Baltimore | Maryland | United States | 21229 |
| 168 | Tufts Medical Center | Boston | Massachusetts | United States | 02111 |
| 169 | Mercy Medical Center | Springfield | Massachusetts | United States | 01104 |
| 170 | Hickman Cancer Center | Adrian | Michigan | United States | 49221 |
| 171 | Saint Joseph Mercy Hospital | Ann Arbor | Michigan | United States | 48106 |
| 172 | University of Michigan Comprehensive Cancer Center | Ann Arbor | Michigan | United States | 48109 |
| 173 | Bronson Battle Creek | Battle Creek | Michigan | United States | 49017 |
| 174 | IHA Hematology Oncology Consultants-Brighton | Brighton | Michigan | United States | 48114 |
| 175 | Saint Joseph Mercy Brighton | Brighton | Michigan | United States | 48114 |
| 176 | Henry Ford Cancer Institute-Downriver | Brownstown | Michigan | United States | 48183 |
| 177 | IHA Hematology Oncology Consultants-Canton | Canton | Michigan | United States | 48188 |
| 178 | Saint Joseph Mercy Canton | Canton | Michigan | United States | 48188 |
| 179 | Caro Cancer Center | Caro | Michigan | United States | 48723 |
| 180 | IHA Hematology Oncology Consultants-Chelsea | Chelsea | Michigan | United States | 48118 |
| 181 | Saint Joseph Mercy Chelsea | Chelsea | Michigan | United States | 48118 |
| 182 | Hematology Oncology Consultants-Clarkston | Clarkston | Michigan | United States | 48346 |
| 183 | Newland Medical Associates-Clarkston | Clarkston | Michigan | United States | 48346 |
| 184 | Henry Ford Macomb Hospital-Clinton Township | Clinton Township | Michigan | United States | 48038 |
| 185 | Henry Ford Medical Center-Fairlane | Dearborn | Michigan | United States | 48126 |
| 186 | Henry Ford Hospital | Detroit | Michigan | United States | 48202 |
| 187 | Ascension Saint John Hospital | Detroit | Michigan | United States | 48236 |
| 188 | Great Lakes Cancer Management Specialists-Doctors Park | East China Township | Michigan | United States | 48054 |
| 189 | Genesee Cancer and Blood Disease Treatment Center | Flint | Michigan | United States | 48503 |
| 190 | Genesee Hematology Oncology PC | Flint | Michigan | United States | 48503 |
| 191 | Genesys Hurley Cancer Institute | Flint | Michigan | United States | 48503 |
| 192 | Hurley Medical Center | Flint | Michigan | United States | 48503 |
| 193 | Helen DeVos Children's Hospital at Spectrum Health | Grand Rapids | Michigan | United States | 49503 |
| 194 | Mercy Health Saint Mary's | Grand Rapids | Michigan | United States | 49503 |
| 195 | Spectrum Health at Butterworth Campus | Grand Rapids | Michigan | United States | 49503 |
| 196 | Academic Hematology Oncology Specialists | Grosse Pointe Woods | Michigan | United States | 48236 |
| 197 | Great Lakes Cancer Management Specialists-Van Elslander Cancer Center | Grosse Pointe Woods | Michigan | United States | 48236 |
| 198 | Michigan Breast Specialists-Grosse Pointe Woods | Grosse Pointe Woods | Michigan | United States | 48236 |
| 199 | Allegiance Health | Jackson | Michigan | United States | 49201 |
| 200 | Bronson Methodist Hospital | Kalamazoo | Michigan | United States | 49007 |
| 201 | West Michigan Cancer Center | Kalamazoo | Michigan | United States | 49007 |
| 202 | Borgess Medical Center | Kalamazoo | Michigan | United States | 49048 |
| 203 | Sparrow Hospital | Lansing | Michigan | United States | 48912 |
| 204 | Hope Cancer Clinic | Livonia | Michigan | United States | 48154 |
| 205 | Saint Mary Mercy Hospital | Livonia | Michigan | United States | 48154 |
| 206 | Great Lakes Cancer Management Specialists-Macomb Medical Campus | Macomb | Michigan | United States | 48044 |
| 207 | Michigan Breast Specialists-Macomb Township | Macomb | Michigan | United States | 48044 |
| 208 | Saint Mary's Oncology/Hematology Associates of Marlette | Marlette | Michigan | United States | 48453 |
| 209 | Toledo Clinic Cancer Centers-Monroe | Monroe | Michigan | United States | 48162 |
| 210 | Mercy Health Mercy Campus | Muskegon | Michigan | United States | 49444 |
| 211 | Lakeland Hospital Niles | Niles | Michigan | United States | 49120 |
| 212 | Cancer and Hematology Centers of Western Michigan - Norton Shores | Norton Shores | Michigan | United States | 49444 |
| 213 | Henry Ford Medical Center-Columbus | Novi | Michigan | United States | 48377 |
| 214 | 21st Century Oncology-Pontiac | Pontiac | Michigan | United States | 48341 |
| 215 | Hope Cancer Center | Pontiac | Michigan | United States | 48341 |
| 216 | Newland Medical Associates-Pontiac | Pontiac | Michigan | United States | 48341 |
| 217 | Saint Joseph Mercy Oakland | Pontiac | Michigan | United States | 48341 |
| 218 | Huron Medical Center PC | Port Huron | Michigan | United States | 48060 |
| 219 | Lake Huron Medical Center | Port Huron | Michigan | United States | 48060 |
| 220 | Spectrum Health Reed City Hospital | Reed City | Michigan | United States | 49677 |
| 221 | Great Lakes Cancer Management Specialists-Rochester Hills | Rochester Hills | Michigan | United States | 48309 |
| 222 | Ascension Saint Mary's Hospital | Saginaw | Michigan | United States | 48601 |
| 223 | Oncology Hematology Associates of Saginaw Valley PC | Saginaw | Michigan | United States | 48604 |
| 224 | Lakeland Medical Center Saint Joseph | Saint Joseph | Michigan | United States | 49085 |
| 225 | Marie Yeager Cancer Center | Saint Joseph | Michigan | United States | 49085 |
| 226 | Henry Ford Macomb Health Center - Shelby Township | Shelby | Michigan | United States | 48315 |
| 227 | Bhadresh Nayak MD PC-Sterling Heights | Sterling Heights | Michigan | United States | 48312 |
| 228 | Ascension Saint Joseph Hospital | Tawas City | Michigan | United States | 48764 |
| 229 | Munson Medical Center | Traverse City | Michigan | United States | 49684 |
| 230 | Advanced Breast Care Center PLLC | Warren | Michigan | United States | 48088 |
| 231 | Great Lakes Cancer Management Specialists-Macomb Professional Building | Warren | Michigan | United States | 48093 |
| 232 | Macomb Hematology Oncology PC | Warren | Michigan | United States | 48093 |
| 233 | Michigan Breast Specialists-Warren | Warren | Michigan | United States | 48093 |
| 234 | Saint John Macomb-Oakland Hospital | Warren | Michigan | United States | 48093 |
| 235 | Henry Ford West Bloomfield Hospital | West Bloomfield | Michigan | United States | 48322 |
| 236 | Saint Mary's Oncology/Hematology Associates of West Branch | West Branch | Michigan | United States | 48661 |
| 237 | Metro Health Hospital | Wyoming | Michigan | United States | 49519 |
| 238 | Huron Gastroenterology PC | Ypsilanti | Michigan | United States | 48106 |
| 239 | IHA Hematology Oncology Consultants-Ann Arbor | Ypsilanti | Michigan | United States | 48197 |
| 240 | Riverwood Healthcare Center | Aitkin | Minnesota | United States | 56431 |
| 241 | Mayo Clinic Health System in Albert Lea | Albert Lea | Minnesota | United States | 56007 |
| 242 | Essentia Health Saint Joseph's Medical Center | Brainerd | Minnesota | United States | 56401 |
| 243 | Fairview Ridges Hospital | Burnsville | Minnesota | United States | 55337 |
| 244 | Minnesota Oncology - Burnsville | Burnsville | Minnesota | United States | 55337 |
| 245 | Cambridge Medical Center | Cambridge | Minnesota | United States | 55008 |
| 246 | Mercy Hospital | Coon Rapids | Minnesota | United States | 55433 |
| 247 | Essentia Health - Deer River Clinic | Deer River | Minnesota | United States | 56636 |
| 248 | Essentia Health Saint Mary's - Detroit Lakes Clinic | Detroit Lakes | Minnesota | United States | 56501 |
| 249 | Essentia Health Cancer Center | Duluth | Minnesota | United States | 55805 |
| 250 | Essentia Health Saint Mary's Medical Center | Duluth | Minnesota | United States | 55805 |
| 251 | Miller-Dwan Hospital | Duluth | Minnesota | United States | 55805 |
| 252 | Fairview Southdale Hospital | Edina | Minnesota | United States | 55435 |
| 253 | Lake Region Healthcare Corporation-Cancer Care | Fergus Falls | Minnesota | United States | 56537 |
| 254 | Essentia Health - Fosston | Fosston | Minnesota | United States | 56542 |
| 255 | Unity Hospital | Fridley | Minnesota | United States | 55432 |
| 256 | Essentia Health Hibbing Clinic | Hibbing | Minnesota | United States | 55746 |
| 257 | Fairview Clinics and Surgery Center Maple Grove | Maple Grove | Minnesota | United States | 55369 |
| 258 | Minnesota Oncology Hematology PA-Maplewood | Maplewood | Minnesota | United States | 55109 |
| 259 | Saint John's Hospital - Healtheast | Maplewood | Minnesota | United States | 55109 |
| 260 | Abbott-Northwestern Hospital | Minneapolis | Minnesota | United States | 55407 |
| 261 | Hennepin County Medical Center | Minneapolis | Minnesota | United States | 55415 |
| 262 | Health Partners Inc | Minneapolis | Minnesota | United States | 55454 |
| 263 | Monticello Cancer Center | Monticello | Minnesota | United States | 55362 |
| 264 | New Ulm Medical Center | New Ulm | Minnesota | United States | 56073 |
| 265 | Essentia Health - Park Rapids | Park Rapids | Minnesota | United States | 56470 |
| 266 | Fairview Northland Medical Center | Princeton | Minnesota | United States | 55371 |
| 267 | North Memorial Medical Health Center | Robbinsdale | Minnesota | United States | 55422 |
| 268 | Mayo Clinic in Rochester | Rochester | Minnesota | United States | 55905 |
| 269 | Park Nicollet Clinic - Saint Louis Park | Saint Louis Park | Minnesota | United States | 55416 |
| 270 | Regions Hospital | Saint Paul | Minnesota | United States | 55101 |
| 271 | United Hospital | Saint Paul | Minnesota | United States | 55102 |
| 272 | Essentia Health Sandstone | Sandstone | Minnesota | United States | 55072 |
| 273 | Saint Francis Regional Medical Center | Shakopee | Minnesota | United States | 55379 |
| 274 | Lakeview Hospital | Stillwater | Minnesota | United States | 55082 |
| 275 | Essentia Health Virginia Clinic | Virginia | Minnesota | United States | 55792 |
| 276 | Ridgeview Medical Center | Waconia | Minnesota | United States | 55387 |
| 277 | Rice Memorial Hospital | Willmar | Minnesota | United States | 56201 |
| 278 | Minnesota Oncology Hematology PA-Woodbury | Woodbury | Minnesota | United States | 55125 |
| 279 | Fairview Lakes Medical Center | Wyoming | Minnesota | United States | 55092 |
| 280 | Saint Louis Cancer and Breast Institute-Ballwin | Ballwin | Missouri | United States | 63011 |
| 281 | Central Care Cancer Center - Bolivar | Bolivar | Missouri | United States | 65613 |
| 282 | Cox Cancer Center Branson | Branson | Missouri | United States | 65616 |
| 283 | Siteman Cancer Center at West County Hospital | Creve Coeur | Missouri | United States | 63141 |
| 284 | Freeman Health System | Joplin | Missouri | United States | 64804 |
| 285 | Mercy Hospital Joplin | Joplin | Missouri | United States | 64804 |
| 286 | Saint Luke's Hospital of Kansas City | Kansas City | Missouri | United States | 64111 |
| 287 | Saint Luke's East - Lee's Summit | Lee's Summit | Missouri | United States | 64086 |
| 288 | Delbert Day Cancer Institute at PCRMC | Rolla | Missouri | United States | 65401 |
| 289 | Mercy Clinic-Rolla-Cancer and Hematology | Rolla | Missouri | United States | 65401 |
| 290 | Heartland Regional Medical Center | Saint Joseph | Missouri | United States | 64506 |
| 291 | Saint Louis Cancer and Breast Institute-South City | Saint Louis | Missouri | United States | 63109 |
| 292 | Washington University School of Medicine | Saint Louis | Missouri | United States | 63110 |
| 293 | Mercy Hospital South | Saint Louis | Missouri | United States | 63128 |
| 294 | Siteman Cancer Center-South County | Saint Louis | Missouri | United States | 63129 |
| 295 | Siteman Cancer Center at Christian Hospital | Saint Louis | Missouri | United States | 63136 |
| 296 | Mercy Hospital Saint Louis | Saint Louis | Missouri | United States | 63141 |
| 297 | Siteman Cancer Center at Saint Peters Hospital | Saint Peters | Missouri | United States | 63376 |
| 298 | Mercy Hospital Springfield | Springfield | Missouri | United States | 65804 |
| 299 | CoxHealth South Hospital | Springfield | Missouri | United States | 65807 |
| 300 | Mercy Hospital Washington | Washington | Missouri | United States | 63090 |
| 301 | Community Hospital of Anaconda | Anaconda | Montana | United States | 59711 |
| 302 | Billings Clinic Cancer Center | Billings | Montana | United States | 59101 |
| 303 | Saint Vincent Healthcare | Billings | Montana | United States | 59101 |
| 304 | Saint Vincent Frontier Cancer Center | Billings | Montana | United States | 59102 |
| 305 | Bozeman Deaconess Hospital | Bozeman | Montana | United States | 59715 |
| 306 | Saint James Community Hospital and Cancer Treatment Center | Butte | Montana | United States | 59701 |
| 307 | Benefis Healthcare- Sletten Cancer Institute | Great Falls | Montana | United States | 59405 |
| 308 | Great Falls Clinic | Great Falls | Montana | United States | 59405 |
| 309 | Kalispell Regional Medical Center | Kalispell | Montana | United States | 59901 |
| 310 | Saint Patrick Hospital - Community Hospital | Missoula | Montana | United States | 59802 |
| 311 | Community Medical Hospital | Missoula | Montana | United States | 59804 |
| 312 | CHI Health Saint Francis | Grand Island | Nebraska | United States | 68803 |
| 313 | CHI Health Good Samaritan | Kearney | Nebraska | United States | 68847 |
| 314 | Saint Elizabeth Regional Medical Center | Lincoln | Nebraska | United States | 68510 |
| 315 | Nebraska Medicine-Village Pointe | Omaha | Nebraska | United States | 68118 |
| 316 | Alegent Health Immanuel Medical Center | Omaha | Nebraska | United States | 68122 |
| 317 | Alegent Health Bergan Mercy Medical Center | Omaha | Nebraska | United States | 68124 |
| 318 | Alegent Health Lakeside Hospital | Omaha | Nebraska | United States | 68130 |
| 319 | Creighton University Medical Center | Omaha | Nebraska | United States | 68131 |
| 320 | University of Nebraska Medical Center | Omaha | Nebraska | United States | 68198 |
| 321 | Midlands Community Hospital | Papillion | Nebraska | United States | 68046 |
| 322 | Carson Tahoe Regional Medical Center | Carson City | Nevada | United States | 89703 |
| 323 | Cancer and Blood Specialists-Henderson | Henderson | Nevada | United States | 89052 |
| 324 | Comprehensive Cancer Centers of Nevada - Henderson | Henderson | Nevada | United States | 89052 |
| 325 | Comprehensive Cancer Centers of Nevada-Horizon Ridge | Henderson | Nevada | United States | 89052 |
| 326 | Las Vegas Cancer Center-Henderson | Henderson | Nevada | United States | 89052 |
| 327 | OptumCare Cancer Care at Seven Hills | Henderson | Nevada | United States | 89052 |
| 328 | 21st Century Oncology-Henderson | Henderson | Nevada | United States | 89074 |
| 329 | Comprehensive Cancer Centers of Nevada-Southeast Henderson | Henderson | Nevada | United States | 89074 |
| 330 | Las Vegas Urology - Green Valley | Henderson | Nevada | United States | 89074 |
| 331 | Las Vegas Urology - Pebble | Henderson | Nevada | United States | 89074 |
| 332 | Urology Specialists of Nevada - Green Valley | Henderson | Nevada | United States | 89074 |
| 333 | Las Vegas Urology - Pecos | Las Vegas | Nevada | United States | 89074 |
| 334 | Desert West Surgery | Las Vegas | Nevada | United States | 89102 |
| 335 | OptumCare Cancer Care at Charleston | Las Vegas | Nevada | United States | 89102 |
| 336 | University Medical Center of Southern Nevada | Las Vegas | Nevada | United States | 89102 |
| 337 | Hope Cancer Care of Nevada | Las Vegas | Nevada | United States | 89103 |
| 338 | Cancer and Blood Specialists-Shadow | Las Vegas | Nevada | United States | 89106 |
| 339 | Radiation Oncology Centers of Nevada Central | Las Vegas | Nevada | United States | 89106 |
| 340 | Urology Specialists of Nevada - Central | Las Vegas | Nevada | United States | 89106 |
| 341 | 21st Century Oncology | Las Vegas | Nevada | United States | 89109 |
| 342 | HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway | Las Vegas | Nevada | United States | 89109 |
| 343 | Sunrise Hospital and Medical Center | Las Vegas | Nevada | United States | 89109 |
| 344 | HealthCare Partners Medical Group Oncology/Hematology-San Martin | Las Vegas | Nevada | United States | 89113 |
| 345 | Las Vegas Prostate Cancer Center | Las Vegas | Nevada | United States | 89113 |
| 346 | Las Vegas Urology - Sunset | Las Vegas | Nevada | United States | 89113 |
| 347 | Urology Specialists of Nevada - Southwest | Las Vegas | Nevada | United States | 89113 |
| 348 | Radiation Oncology Centers of Nevada Southeast | Las Vegas | Nevada | United States | 89119 |
| 349 | 21st Century Oncology-Vegas Tenaya | Las Vegas | Nevada | United States | 89128 |
| 350 | Ann M Wierman MD LTD | Las Vegas | Nevada | United States | 89128 |
| 351 | Cancer and Blood Specialists-Tenaya | Las Vegas | Nevada | United States | 89128 |
| 352 | Comprehensive Cancer Centers of Nevada - Northwest | Las Vegas | Nevada | United States | 89128 |
| 353 | HealthCare Partners Medical Group Oncology/Hematology-Tenaya | Las Vegas | Nevada | United States | 89128 |
| 354 | Las Vegas Urology - Cathedral Rock | Las Vegas | Nevada | United States | 89128 |
| 355 | Las Vegas Urology - Smoke Ranch | Las Vegas | Nevada | United States | 89128 |
| 356 | OptumCare Cancer Care at MountainView | Las Vegas | Nevada | United States | 89128 |
| 357 | Urology Specialists of Nevada - Northwest | Las Vegas | Nevada | United States | 89128 |
| 358 | Alliance for Childhood Diseases/Cure 4 the Kids Foundation | Las Vegas | Nevada | United States | 89135 |
| 359 | Comprehensive Cancer Centers of Nevada - Town Center | Las Vegas | Nevada | United States | 89144 |
| 360 | Comprehensive Cancer Centers of Nevada-Summerlin | Las Vegas | Nevada | United States | 89144 |
| 361 | Summerlin Hospital Medical Center | Las Vegas | Nevada | United States | 89144 |
| 362 | Las Vegas Cancer Center-Medical Center | Las Vegas | Nevada | United States | 89148-2405 |
| 363 | 21st Century Oncology-Fort Apache | Las Vegas | Nevada | United States | 89148 |
| 364 | Comprehensive Cancer Centers of Nevada | Las Vegas | Nevada | United States | 89148 |
| 365 | OptumCare Cancer Care at Fort Apache | Las Vegas | Nevada | United States | 89148 |
| 366 | HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills | Las Vegas | Nevada | United States | 89149 |
| 367 | Comprehensive Cancer Centers of Nevada - Central Valley | Las Vegas | Nevada | United States | 89169 |
| 368 | University Cancer Center | Las Vegas | Nevada | United States | 89169 |
| 369 | Hope Cancer Care of Nevada-Pahrump | Pahrump | Nevada | United States | 89048 |
| 370 | Renown Regional Medical Center | Reno | Nevada | United States | 89502 |
| 371 | Saint Mary's Regional Medical Center | Reno | Nevada | United States | 89503 |
| 372 | Radiation Oncology Associates | Reno | Nevada | United States | 89509 |
| 373 | Morristown Medical Center | Morristown | New Jersey | United States | 07960 |
| 374 | Glens Falls Hospital | Glens Falls | New York | United States | 12801 |
| 375 | UNC Lineberger Comprehensive Cancer Center | Chapel Hill | North Carolina | United States | 27599 |
| 376 | Carolinas Medical Center/Levine Cancer Institute | Charlotte | North Carolina | United States | 28203 |
| 377 | Vidant Oncology-Kenansville | Kenansville | North Carolina | United States | 28349 |
| 378 | Vidant Oncology-Kinston | Kinston | North Carolina | United States | 28501 |
| 379 | Vidant Oncology-Richlands | Richlands | North Carolina | United States | 28574 |
| 380 | Essentia Health Cancer Center-South University Clinic | Fargo | North Dakota | United States | 58103 |
| 381 | Essentia Health - Jamestown Clinic | Jamestown | North Dakota | United States | 58401 |
| 382 | Indu and Raj Soin Medical Center | Beavercreek | Ohio | United States | 45431 |
| 383 | Strecker Cancer Center-Belpre | Belpre | Ohio | United States | 45714 |
| 384 | Saint Elizabeth Boardman Hospital | Boardman | Ohio | United States | 44512 |
| 385 | Dayton Physicians LLC-Miami Valley South | Centerville | Ohio | United States | 45459 |
| 386 | Miami Valley Hospital South | Centerville | Ohio | United States | 45459 |
| 387 | Geauga Hospital | Chardon | Ohio | United States | 44024 |
| 388 | Adena Regional Medical Center | Chillicothe | Ohio | United States | 45601 |
| 389 | Good Samaritan Hospital - Cincinnati | Cincinnati | Ohio | United States | 45220 |
| 390 | Oncology Hematology Care Inc-Kenwood | Cincinnati | Ohio | United States | 45236 |
| 391 | Bethesda North Hospital | Cincinnati | Ohio | United States | 45242 |
| 392 | TriHealth Cancer Institute-Westside | Cincinnati | Ohio | United States | 45247 |
| 393 | TriHealth Cancer Institute-Anderson | Cincinnati | Ohio | United States | 45255 |
| 394 | Case Western Reserve University | Cleveland | Ohio | United States | 44106 |
| 395 | MetroHealth Medical Center | Cleveland | Ohio | United States | 44109 |
| 396 | Cleveland Clinic Foundation | Cleveland | Ohio | United States | 44195 |
| 397 | Mount Carmel East Hospital | Columbus | Ohio | United States | 43213 |
| 398 | Columbus Oncology and Hematology Associates Inc | Columbus | Ohio | United States | 43214 |
| 399 | Riverside Methodist Hospital | Columbus | Ohio | United States | 43214 |
| 400 | Grant Medical Center | Columbus | Ohio | United States | 43215 |
| 401 | The Mark H Zangmeister Center | Columbus | Ohio | United States | 43219 |
| 402 | Mount Carmel Health Center West | Columbus | Ohio | United States | 43222 |
| 403 | Doctors Hospital | Columbus | Ohio | United States | 43228 |
| 404 | Good Samaritan Hospital - Dayton | Dayton | Ohio | United States | 45406 |
| 405 | Miami Valley Hospital | Dayton | Ohio | United States | 45409 |
| 406 | Dayton Physician LLC-Miami Valley Hospital North | Dayton | Ohio | United States | 45415 |
| 407 | Miami Valley Hospital North | Dayton | Ohio | United States | 45415 |
| 408 | Dayton Veterans Affairs Medical Center | Dayton | Ohio | United States | 45428 |
| 409 | Delaware Health Center-Grady Cancer Center | Delaware | Ohio | United States | 43015 |
| 410 | Grady Memorial Hospital | Delaware | Ohio | United States | 43015 |
| 411 | Dublin Methodist Hospital | Dublin | Ohio | United States | 43016 |
| 412 | Armes Family Cancer Center | Findlay | Ohio | United States | 45840 |
| 413 | Blanchard Valley Hospital | Findlay | Ohio | United States | 45840 |
| 414 | Orion Cancer Care | Findlay | Ohio | United States | 45840 |
| 415 | Atrium Medical Center-Middletown Regional Hospital | Franklin | Ohio | United States | 45005-1066 |
| 416 | Dayton Physicians LLC-Atrium | Franklin | Ohio | United States | 45005 |
| 417 | Central Ohio Breast and Endocrine Surgery | Gahanna | Ohio | United States | 43230 |
| 418 | Dayton Physicians LLC-Wayne | Greenville | Ohio | United States | 45331 |
| 419 | Wayne Hospital | Greenville | Ohio | United States | 45331 |
| 420 | Mount Carmel Grove City Hospital | Grove City | Ohio | United States | 43123 |
| 421 | Greater Dayton Cancer Center | Kettering | Ohio | United States | 45409 |
| 422 | First Dayton Cancer Care | Kettering | Ohio | United States | 45420 |
| 423 | Kettering Medical Center | Kettering | Ohio | United States | 45429 |
| 424 | Fairfield Medical Center | Lancaster | Ohio | United States | 43130 |
| 425 | Saint Rita's Medical Center | Lima | Ohio | United States | 45801 |
| 426 | OhioHealth Mansfield Hospital | Mansfield | Ohio | United States | 44903 |
| 427 | Marietta Memorial Hospital | Marietta | Ohio | United States | 45750 |
| 428 | OhioHealth Marion General Hospital | Marion | Ohio | United States | 43302 |
| 429 | UH Seidman Cancer Center at Landerbrook Health Center | Mayfield Heights | Ohio | United States | 44124 |
| 430 | UH Seidman Cancer Center at Lake Health Mentor Campus | Mentor | Ohio | United States | 44060 |
| 431 | UH Seidman Cancer Center at Southwest General Hospital | Middleburg Heights | Ohio | United States | 44130 |
| 432 | Knox Community Hospital | Mount Vernon | Ohio | United States | 43050 |
| 433 | Licking Memorial Hospital | Newark | Ohio | United States | 43055 |
| 434 | Newark Radiation Oncology | Newark | Ohio | United States | 43055 |
| 435 | Mercy Health Perrysburg Cancer Center | Perrysburg | Ohio | United States | 43551 |
| 436 | Southern Ohio Medical Center | Portsmouth | Ohio | United States | 45662 |
| 437 | UH Seidman Cancer Center at Firelands Regional Medical Center | Sandusky | Ohio | United States | 44870 |
| 438 | Springfield Regional Cancer Center | Springfield | Ohio | United States | 45504 |
| 439 | Springfield Regional Medical Center | Springfield | Ohio | United States | 45505 |
| 440 | Saint Vincent Mercy Medical Center | Toledo | Ohio | United States | 43608 |
| 441 | Mercy Health - Saint Anne Hospital | Toledo | Ohio | United States | 43623 |
| 442 | Toledo Clinic Cancer Centers-Toledo | Toledo | Ohio | United States | 43623 |
| 443 | Dayton Physicians LLC-Upper Valley | Troy | Ohio | United States | 45373 |
| 444 | Upper Valley Medical Center | Troy | Ohio | United States | 45373 |
| 445 | Saint Joseph Warren Hospital | Warren | Ohio | United States | 44484 |
| 446 | Saint Ann's Hospital | Westerville | Ohio | United States | 43081 |
| 447 | UH Seidman Cancer Center at Saint John Medical Center | Westlake | Ohio | United States | 44145 |
| 448 | Saint Elizabeth Youngstown Hospital | Youngstown | Ohio | United States | 44501 |
| 449 | Genesis Healthcare System Cancer Care Center | Zanesville | Ohio | United States | 43701 |
| 450 | Mercy Hospital Oklahoma City | Oklahoma City | Oklahoma | United States | 73120 |
| 451 | Saint Alphonsus Medical Center-Baker City | Baker City | Oregon | United States | 97814 |
| 452 | Saint Charles Health System | Bend | Oregon | United States | 97701 |
| 453 | Clackamas Radiation Oncology Center | Clackamas | Oregon | United States | 97015 |
| 454 | Providence Cancer Institute Clackamas Clinic | Clackamas | Oregon | United States | 97015 |
| 455 | Bay Area Hospital | Coos Bay | Oregon | United States | 97420 |
| 456 | Providence Newberg Medical Center | Newberg | Oregon | United States | 97132 |
| 457 | Saint Alphonsus Medical Center-Ontario | Ontario | Oregon | United States | 97914 |
| 458 | Providence Portland Medical Center | Portland | Oregon | United States | 97213 |
| 459 | Providence Saint Vincent Medical Center | Portland | Oregon | United States | 97225 |
| 460 | Oregon Health and Science University | Portland | Oregon | United States | 97239 |
| 461 | Saint Charles Health System-Redmond | Redmond | Oregon | United States | 97756 |
| 462 | Lehigh Valley Hospital-Cedar Crest | Allentown | Pennsylvania | United States | 18103 |
| 463 | Lehigh Valley Hospital - Muhlenberg | Bethlehem | Pennsylvania | United States | 18017 |
| 464 | Geisinger Medical Center | Danville | Pennsylvania | United States | 17822 |
| 465 | Pocono Medical Center | East Stroudsburg | Pennsylvania | United States | 18301 |
| 466 | Geisinger Medical Center-Cancer Center Hazleton | Hazleton | Pennsylvania | United States | 18201 |
| 467 | Lehigh Valley Hospital-Hazleton | Hazleton | Pennsylvania | United States | 18201 |
| 468 | Geisinger Medical Oncology-Lewisburg | Lewisburg | Pennsylvania | United States | 17837 |
| 469 | Lewistown Hospital | Lewistown | Pennsylvania | United States | 17044 |
| 470 | Thomas Jefferson University Hospital | Philadelphia | Pennsylvania | United States | 19107 |
| 471 | Allegheny General Hospital | Pittsburgh | Pennsylvania | United States | 15212 |
| 472 | West Penn Hospital | Pittsburgh | Pennsylvania | United States | 15224 |
| 473 | Pottstown Hospital | Pottstown | Pennsylvania | United States | 19464 |
| 474 | Geisinger Cancer Services-Pottsville | Pottsville | Pennsylvania | United States | 17901 |
| 475 | Community Medical Center | Scranton | Pennsylvania | United States | 18510 |
| 476 | Geisinger Medical Oncology-Selinsgrove | Selinsgrove | Pennsylvania | United States | 17870 |
| 477 | Geisinger Medical Group | State College | Pennsylvania | United States | 16801 |
| 478 | Reading Hospital | West Reading | Pennsylvania | United States | 19611 |
| 479 | Geisinger Wyoming Valley/Henry Cancer Center | Wilkes-Barre | Pennsylvania | United States | 18711 |
| 480 | Smilow Cancer Hospital Care Center - Westerly | Westerly | Rhode Island | United States | 02891 |
| 481 | Prisma Health Cancer Institute - Spartanburg | Boiling Springs | South Carolina | United States | 29316 |
| 482 | Medical University of South Carolina | Charleston | South Carolina | United States | 29425 |
| 483 | Prisma Health Cancer Institute - Easley | Easley | South Carolina | United States | 29640 |
| 484 | Prisma Health Cancer Institute - Butternut | Greenville | South Carolina | United States | 29605 |
| 485 | Prisma Health Cancer Institute - Faris | Greenville | South Carolina | United States | 29605 |
| 486 | Prisma Health Greenville Memorial Hospital | Greenville | South Carolina | United States | 29605 |
| 487 | Prisma Health Cancer Institute - Eastside | Greenville | South Carolina | United States | 29615 |
| 488 | Self Regional Healthcare | Greenwood | South Carolina | United States | 29646 |
| 489 | Prisma Health Cancer Institute - Greer | Greer | South Carolina | United States | 29650 |
| 490 | Prisma Health Cancer Institute - Seneca | Seneca | South Carolina | United States | 29672 |
| 491 | Avera Cancer Institute | Sioux Falls | South Dakota | United States | 57105 |
| 492 | Saint Joseph Regional Cancer Center | Bryan | Texas | United States | 77802 |
| 493 | UT Southwestern/Simmons Cancer Center-Dallas | Dallas | Texas | United States | 75390 |
| 494 | UT Southwestern/Simmons Cancer Center-Fort Worth | Fort Worth | Texas | United States | 76104 |
| 495 | M D Anderson Cancer Center | Houston | Texas | United States | 77030 |
| 496 | UT Southwestern Clinical Center at Richardson/Plano | Richardson | Texas | United States | 75080 |
| 497 | American Fork Hospital / Huntsman Intermountain Cancer Center | American Fork | Utah | United States | 84003 |
| 498 | Sandra L Maxwell Cancer Center | Cedar City | Utah | United States | 84720 |
| 499 | Logan Regional Hospital | Logan | Utah | United States | 84321 |
| 500 | Intermountain Medical Center | Murray | Utah | United States | 84107 |
| 501 | McKay-Dee Hospital Center | Ogden | Utah | United States | 84403 |
| 502 | Utah Valley Regional Medical Center | Provo | Utah | United States | 84604 |
| 503 | Riverton Hospital | Riverton | Utah | United States | 84065 |
| 504 | Dixie Medical Center Regional Cancer Center | Saint George | Utah | United States | 84770 |
| 505 | Utah Cancer Specialists-Salt Lake City | Salt Lake City | Utah | United States | 84106 |
| 506 | Huntsman Cancer Institute/University of Utah | Salt Lake City | Utah | United States | 84112 |
| 507 | LDS Hospital | Salt Lake City | Utah | United States | 84143 |
| 508 | University of Virginia Cancer Center | Charlottesville | Virginia | United States | 22908 |
| 509 | Providence Regional Cancer System-Aberdeen | Aberdeen | Washington | United States | 98520 |
| 510 | MultiCare Auburn Medical Center | Auburn | Washington | United States | 98001 |
| 511 | Overlake Medical Center | Bellevue | Washington | United States | 98004 |
| 512 | PeaceHealth Saint Joseph Medical Center | Bellingham | Washington | United States | 98225 |
| 513 | Harrison HealthPartners Hematology and Oncology-Bremerton | Bremerton | Washington | United States | 98310 |
| 514 | Harrison Medical Center | Bremerton | Washington | United States | 98310 |
| 515 | Highline Medical Center-Main Campus | Burien | Washington | United States | 98166 |
| 516 | Providence Regional Cancer System-Centralia | Centralia | Washington | United States | 98531 |
| 517 | Swedish Cancer Institute-Edmonds | Edmonds | Washington | United States | 98026 |
| 518 | Saint Elizabeth Hospital | Enumclaw | Washington | United States | 98022 |
| 519 | Providence Regional Cancer Partnership | Everett | Washington | United States | 98201 |
| 520 | Saint Francis Hospital | Federal Way | Washington | United States | 98003 |
| 521 | MultiCare Gig Harbor Medical Park | Gig Harbor | Washington | United States | 98335 |
| 522 | Swedish Cancer Institute-Issaquah | Issaquah | Washington | United States | 98029 |
| 523 | Kadlec Clinic Hematology and Oncology | Kennewick | Washington | United States | 99336 |
| 524 | Providence Regional Cancer System-Lacey | Lacey | Washington | United States | 98503 |
| 525 | Saint Clare Hospital | Lakewood | Washington | United States | 98499 |
| 526 | PeaceHealth Saint John Medical Center | Longview | Washington | United States | 98632 |
| 527 | Jefferson Healthcare | Port Townsend | Washington | United States | 98368 |
| 528 | Harrison HealthPartners Hematology and Oncology-Poulsbo | Poulsbo | Washington | United States | 98370 |
| 529 | MultiCare Good Samaritan Hospital | Puyallup | Washington | United States | 98372 |
| 530 | Valley Medical Center | Renton | Washington | United States | 98055 |
| 531 | Pacific Gynecology Specialists | Seattle | Washington | United States | 98104 |
| 532 | Swedish Medical Center-Ballard Campus | Seattle | Washington | United States | 98107 |
| 533 | Fred Hutchinson Cancer Research Center | Seattle | Washington | United States | 98109 |
| 534 | Seattle Cancer Care Alliance | Seattle | Washington | United States | 98109 |
| 535 | Swedish Medical Center-First Hill | Seattle | Washington | United States | 98122-4307 |
| 536 | Swedish Medical Center-Cherry Hill | Seattle | Washington | United States | 98122-5711 |
| 537 | Seattle Cancer Care Alliance at Northwest Hospital | Seattle | Washington | United States | 98133 |
| 538 | University of Washington Medical Center - Montlake | Seattle | Washington | United States | 98195 |
| 539 | PeaceHealth United General Medical Center | Sedro-Woolley | Washington | United States | 98284 |
| 540 | Providence Regional Cancer System-Shelton | Shelton | Washington | United States | 98584 |
| 541 | MultiCare Deaconess Cancer and Blood Specialty Center - Valley | Spokane Valley | Washington | United States | 99216 |
| 542 | MultiCare Deaconess Cancer and Blood Specialty Center - Downtown | Spokane | Washington | United States | 99204 |
| 543 | MultiCare Deaconess Cancer and Blood Specialty Center - North | Spokane | Washington | United States | 99218 |
| 544 | Franciscan Research Center-Northwest Medical Plaza | Tacoma | Washington | United States | 98405 |
| 545 | Mary Bridge Children's Hospital and Health Center | Tacoma | Washington | United States | 98405 |
| 546 | MultiCare Tacoma General Hospital | Tacoma | Washington | United States | 98405 |
| 547 | PeaceHealth Southwest Medical Center | Vancouver | Washington | United States | 98664 |
| 548 | Providence Saint Mary Regional Cancer Center | Walla Walla | Washington | United States | 99362 |
| 549 | North Star Lodge Cancer Center at Yakima Valley Memorial Hospital | Yakima | Washington | United States | 98902 |
| 550 | Providence Regional Cancer System-Yelm | Yelm | Washington | United States | 98597 |
| 551 | United Hospital Center | Bridgeport | West Virginia | United States | 26330 |
| 552 | West Virginia University Charleston Division | Charleston | West Virginia | United States | 25304 |
| 553 | WVUH-Berkely Medical Center | Martinsburg | West Virginia | United States | 25401 |
| 554 | West Virginia University Healthcare | Morgantown | West Virginia | United States | 26506 |
| 555 | Camden Clark Medical Center | Parkersburg | West Virginia | United States | 26101 |
| 556 | ThedaCare Regional Cancer Center | Appleton | Wisconsin | United States | 54911 |
| 557 | Duluth Clinic Ashland | Ashland | Wisconsin | United States | 54806 |
| 558 | Northwest Wisconsin Cancer Center | Ashland | Wisconsin | United States | 54806 |
| 559 | Aurora Cancer Care-Southern Lakes VLCC | Burlington | Wisconsin | United States | 53105 |
| 560 | Marshfield Medical Center-EC Cancer Center | Eau Claire | Wisconsin | United States | 54701 |
| 561 | Mayo Clinic Health System-Eau Claire Clinic | Eau Claire | Wisconsin | United States | 54701 |
| 562 | Aurora Health Center-Fond du Lac | Fond Du Lac | Wisconsin | United States | 54937 |
| 563 | Aurora Health Care Germantown Health Center | Germantown | Wisconsin | United States | 53022 |
| 564 | Aurora Cancer Care-Grafton | Grafton | Wisconsin | United States | 53024 |
| 565 | Saint Vincent Hospital Cancer Center Green Bay | Green Bay | Wisconsin | United States | 54301 |
| 566 | Saint Vincent Hospital Cancer Center at Saint Mary's | Green Bay | Wisconsin | United States | 54303 |
| 567 | Aurora BayCare Medical Center | Green Bay | Wisconsin | United States | 54311 |
| 568 | Aurora Cancer Care-Kenosha South | Kenosha | Wisconsin | United States | 53142 |
| 569 | Gundersen Lutheran Medical Center | La Crosse | Wisconsin | United States | 54601 |
| 570 | University of Wisconsin Hospital and Clinics | Madison | Wisconsin | United States | 53792 |
| 571 | Aurora Bay Area Medical Group-Marinette | Marinette | Wisconsin | United States | 54143 |
| 572 | Marshfield Medical Center-Marshfield | Marshfield | Wisconsin | United States | 54449 |
| 573 | Aurora Cancer Care-Milwaukee | Milwaukee | Wisconsin | United States | 53209 |
| 574 | Aurora Saint Luke's Medical Center | Milwaukee | Wisconsin | United States | 53215 |
| 575 | Aurora Sinai Medical Center | Milwaukee | Wisconsin | United States | 53233 |
| 576 | Marshfield Clinic-Minocqua Center | Minocqua | Wisconsin | United States | 54548 |
| 577 | ProHealth D N Greenwald Center | Mukwonago | Wisconsin | United States | 53149 |
| 578 | Cancer Center of Western Wisconsin | New Richmond | Wisconsin | United States | 54017 |
| 579 | ProHealth Oconomowoc Memorial Hospital | Oconomowoc | Wisconsin | United States | 53066 |
| 580 | Saint Vincent Hospital Cancer Center at Oconto Falls | Oconto Falls | Wisconsin | United States | 54154 |
| 581 | Vince Lombardi Cancer Clinic - Oshkosh | Oshkosh | Wisconsin | United States | 54904 |
| 582 | Aurora Cancer Care-Racine | Racine | Wisconsin | United States | 53406 |
| 583 | Marshfield Medical Center-Rice Lake | Rice Lake | Wisconsin | United States | 54868 |
| 584 | Vince Lombardi Cancer Clinic-Sheboygan | Sheboygan | Wisconsin | United States | 53081 |
| 585 | Marshfield Clinic Stevens Point Center | Stevens Point | Wisconsin | United States | 54482 |
| 586 | Saint Vincent Hospital Cancer Center at Sturgeon Bay | Sturgeon Bay | Wisconsin | United States | 54235-1495 |
| 587 | Aurora Medical Center in Summit | Summit | Wisconsin | United States | 53066 |
| 588 | Vince Lombardi Cancer Clinic-Two Rivers | Two Rivers | Wisconsin | United States | 54241 |
| 589 | ProHealth Waukesha Memorial Hospital | Waukesha | Wisconsin | United States | 53188 |
| 590 | UW Cancer Center at ProHealth Care | Waukesha | Wisconsin | United States | 53188 |
| 591 | Aurora Cancer Care-Milwaukee West | Wauwatosa | Wisconsin | United States | 53226 |
| 592 | Aurora West Allis Medical Center | West Allis | Wisconsin | United States | 53227 |
| 593 | Marshfield Medical Center - Weston | Weston | Wisconsin | United States | 54476 |
| 594 | Cheyenne Regional Medical Center-West | Cheyenne | Wyoming | United States | 82001 |
| 595 | Billings Clinic-Cody | Cody | Wyoming | United States | 82414 |
| 596 | Welch Cancer Center | Sheridan | Wyoming | United States | 82801 |
Sponsors and Collaborators
- ECOG-ACRIN Cancer Research Group
- National Cancer Institute (NCI)
Investigators
- Principal Investigator: Natalie S Callander, ECOG-ACRIN Cancer Research Group
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- EAA173
- NCI-2018-02611
- EAA173
- EAA173
- U10CA180820