Clincosm LogoSign in Get a demo

SNP-based Prediction of Recurrence Risk in Kidney Stone Patients

Sponsor
The First Affiliated Hospital of Guangzhou Medical University (Other)
Overall Status
Recruiting
CT.gov ID
NCT04937192
Collaborator
Xiangya Hospital of Central South University (Other), Wuhan University Renmin Hospital (Other), The Second Affiliated Hospital of Kunming Medical University (Other), The 2nd.Hospital of Tianjin Medical University (Other), Shenzhen People's Hospital (Other), 301 Hospital (Other), Zhongda Hospital Southeast University (Other), People's Hospital of Xinjiang (Other), ZhuZhou Central Hospital (Other), Baoshan No.2 People's Hospital (Other), Guangdong No.2 People's Hospital (Other), Dehong People's Hospital (Other), Second Affiliated Hospital of Guangzhou Medical University (Other), Jiangmen Central Hospital (Other), Huizhou Municipal Central Hospital (Other), Yongzhou Center Hospital (Other), Shenzhen Longgang Central Hospital (Other)
1,300
Enrollment
1
Location
131.9
Anticipated Duration (Months)
9.9
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The goal of this study is to gain new knowledge about genetic risk factors that may affect the kidney stone recurrence. The study seeks to understand if different forms of genes result in an increased risk of kidney stone recurrence.

Condition or Disease Intervention/Treatment Phase
  • Other: No intervention

Detailed Description

In this study, investigators are prospectively testing whether SNP are associated with kidney stone recurrence. Investigators will test the hypothesis that SNP predispose kidney stone patients to recurrence.

Investigators hope to identify predictors for the kidney stone recurrence. This would allow the identification of a subpopulation of kidney stone patients that would benefit most from prevention measures.

Study Design

Study Type:
Observational
Anticipated Enrollment :
1300 participants
Observational Model:
Cohort
Time Perspective:
Prospective
Official Title:
SNP-based Prediction of Recurrence Risk in Kidney Stone Patients: a Prospective Multicenter Observational Study
Actual Study Start Date :
Jan 1, 2013
Anticipated Primary Completion Date :
Dec 31, 2022
Anticipated Study Completion Date :
Dec 31, 2023

Arms and Interventions

Arm Intervention/Treatment
Kidney stone former

Other: No intervention
No intervention

Outcome Measures

Primary Outcome Measures

  1. Stone-free survival [From date of stone-free until the date of first stone recurrence (up to 7 years)]

    Time to first stone recurrence from stone-free

Eligibility Criteria

Criteria

Ages Eligible for Study:
18 Years and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:

  • Age 18 or older

  • Kidney stone former who the stone was removed completely.

  • Ability to give informed consent

Exclusion Criteria:
  • Patient refuses or is unable to give consent

Contacts and Locations

Locations

Site City State Country Postal Code
1 The First Affiliated Hospital of Guangzhou Medical University Guangzhou Guangdong China 510120

Sponsors and Collaborators

  • The First Affiliated Hospital of Guangzhou Medical University
  • Xiangya Hospital of Central South University
  • Wuhan University Renmin Hospital
  • The Second Affiliated Hospital of Kunming Medical University
  • The 2nd.Hospital of Tianjin Medical University
  • Shenzhen People's Hospital
  • 301 Hospital
  • Zhongda Hospital Southeast University
  • People's Hospital of Xinjiang
  • ZhuZhou Central Hospital
  • Baoshan No.2 People's Hospital
  • Guangdong No.2 People's Hospital
  • Dehong People's Hospital
  • Second Affiliated Hospital of Guangzhou Medical University
  • Jiangmen Central Hospital
  • Huizhou Municipal Central Hospital
  • Yongzhou Center Hospital
  • Shenzhen Longgang Central Hospital

Investigators

  • Principal Investigator: Guohua Zeng, M.D., The First Affiliated Hospital of Guangzhou Medical University

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Guohua Zeng, Vice president, The First Affiliated Hospital of Guangzhou Medical University
ClinicalTrials.gov Identifier:
NCT04937192
Other Study ID Numbers:
  • MRER2013-001
First Posted:
Jun 23, 2021
Last Update Posted:
Jun 23, 2021
Last Verified:
Jun 1, 2021
Individual Participant Data (IPD) Sharing Statement:
Undecided
Plan to Share IPD:
Undecided
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Keywords provided by Guohua Zeng, Vice president, The First Affiliated Hospital of Guangzhou Medical University
SNP
Kidney stone
Recurrence
Additional relevant MeSH terms:
Kidney Calculi
Nephrolithiasis
Recurrence
Calculi

Study Results

No Results Posted as of Jun 23, 2021