Evaluation of Some Prognostic Factors in Acute Aluminum Phosphide Intoxicated Cases

• Sponsor: Zagazig University (Other)
• Overall Status: Completed
• CT.gov ID: NCT05215444
• Collaborator: (none)
• Enrollment: 42
• Location: 1
• Actual Duration (Months): 5.9
• Patients Per Site Per Month: 7.1

Study Details

Study Description

Brief Summary

study of some laboratory and clinical findings which may show the severity of aluminium phosphide toxicity and the need of the cases to be admitted to ICU

Condition or Disease	Intervention/Treatment	Phase
Aluminum Phosphide Poisoning	Diagnostic Test: some prognostic factors

Detailed Description

aluminium phosphide poisoning is a major cause of death in intoxicated and suicidal cases since there is no antidote and there is no specific investigation for it so there is a need for further study to identify the cause of death and the most specific investigation in the case of AlP toxicity

Study Design

• Study Type: Observational
• Actual Enrollment: 42 participants
• Observational Model: Cohort
• Time Perspective: Prospective
• Official Title: Evaluation of Some Prognostic Factors in Acute Aluminum Phosphide Intoxicated Cases
• Actual Study Start Date: Jan 1, 2021
• Actual Primary Completion Date: Jan 30, 2021
• Actual Study Completion Date: Jun 30, 2021

Arms and Interventions

Arm	Intervention/Treatment
survivors	Diagnostic Test: some prognostic factors; cortisol level, renin, troponin I, MDA ,catalase, super oxide dismutase, liver functions, kidney functions, arterial blood gases, sodium level, potassium level. white blood cells count
non survivors	Diagnostic Test: some prognostic factors; cortisol level, renin, troponin I, MDA ,catalase, super oxide dismutase, liver functions, kidney functions, arterial blood gases, sodium level, potassium level. white blood cells count

Outcome Measures

Primary Outcome Measures

1. prognosis [the first 24 post poisoning]

   predict the mortality of intoxicated AlP cases

Eligibility Criteria

Criteria

• Ages Eligible for Study: 15 Years to 45 Years
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: Yes

Inclusion Criteria:

1. History of exposure or intake of Aluminum phosphide.

2. Clinical picture of Acute Aluminum phosphide poisoning including severe vomiting, hypotension, abdominal pain, cardio-pulmonary distress.

3. Cases of the age of 15 to 45 years old

Exclusion Criteria:

• 1. Cases with an unclear history. 2. History of co-morbidities or systemic diseases because of the possibility of misleading laboratory results.

1. History of co-ingestion of drugs or another poison.

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Faculty of Medicine Zagazig University	Zagazig	Sharkia	Egypt	44511

Sponsors and Collaborators

• Zagazig University

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: shymaa mohamed nasrallah, demonstrator, Zagazig University
• ClinicalTrials.gov Identifier: NCT05215444
• Other Study ID Numbers: 6655
• First Posted: Jan 31, 2022
• Last Update Posted: Jan 31, 2022
• Last Verified: Jan 1, 2022

• Individual Participant Data (IPD) Sharing Statement: No
• Plan to Share IPD: No
• Additional relevant MeSH terms: Poisoning

Study Results

No Results Posted as of Jan 31, 2022