Diagnostic Value of HS-CRP in Stable Angina.

• Sponsor: Shiraz University of Medical Sciences (Other)
• Overall Status: Completed
• CT.gov ID: NCT00719992
• Collaborator: (none)
• Enrollment: 97
• Location: 1
• Arms: 2
• Duration (Months): 16
• Patients Per Site Per Month: 6.1

Study Details

Study Description

Brief Summary

The aim of this study was to assess the amount of additive value of HS-CRP levels to a positive exercise tolerance test (ETT) in predicting coronary artery disease (CAD) using coronary angiography as the gold standard. The investigators concluded that HS-CRP can be used as a single predictor of coronary vessel involvement in patients with stable angina and positive ETT.

Condition or Disease	Intervention/Treatment	Phase
Stable Angina; Positive ETT	Procedure: coronary angiography	N/A

Detailed Description

the investigators included 97 patients with positive ETT and stable angina and saw that Hs-CRP is the only predictor of severity of CAD as compared with coronary angiography in stable angina patients.

Study Design

• Study Type: Interventional
• Actual Enrollment: 97 participants
• Allocation: Non-Randomized
• Intervention Model: Parallel Assignment
• Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
• Primary Purpose: Diagnostic
• Official Title: Diagnostic Value of HS-CRP in Stable Angina Patients With Positive Exercise Test as Compared With Coronary Angiography.
• Study Start Date: Apr 1, 2006
• Actual Primary Completion Date: Aug 1, 2007
• Actual Study Completion Date: Aug 1, 2007

Arms and Interventions

Arm	Intervention/Treatment
Experimental: 1 positive ETT, High HS-CRP	Procedure: coronary angiography; effect of level of HS-CRP
Active Comparator: 2 positive ETT, Low HS-CRP	Procedure: coronary angiography; effect of level of HS-CRP

Outcome Measures

Primary Outcome Measures

1. significant coronary lesion []

Secondary Outcome Measures

1. severity of CAD []

Eligibility Criteria

Criteria

• Ages Eligible for Study: 43 Years to 64 Years
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:

• Stable angina

• Positive ETT

Exclusion Criteria:

• Unability to perform ETT

• Contraindications for ETT and angiography study

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Cardiology Ward Shiraz University of Medical Sciences	Shiraz	Fars	Iran, Islamic Republic of	51318

Sponsors and Collaborators

• Shiraz University of Medical Sciences

Investigators

• Study Director: javad kojuri, M.D., Shiraz University of Medical Sciences

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• ClinicalTrials.gov Identifier: NCT00719992
• Other Study ID Numbers: 4543
• First Posted: Jul 22, 2008
• Last Update Posted: Jul 22, 2008
• Last Verified: Jul 1, 2008

• Keywords provided by , ,: Exercise tolerance test; HS-CRP; Coronary angiography; Patients
• Additional relevant MeSH terms: Angina Pectoris; Angina, Stable

Study Results

No Results Posted as of Jul 22, 2008