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STIF-CTS: Stiffness of the Skin and Joints in Relation to Carpal Tunnel Syndrome

Sponsor
St. Antonius Hospital (Other)
Overall Status
Unknown status
CT.gov ID
NCT01081860
Collaborator
(none)
40
Enrollment
1
Location
7
Duration (Months)
5.7
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The exact etiology of CTS remains yet unknown. A rise in carpal tunnel pressure is well documented, but why this phenomenon occurs is yet unknown in most patients. There is an absolute or relative narrowing of the carpal tunnel, which results in a compression of the median nerve.

The investigators postulate, that a stiffer flexor retinaculum (roof of carpal tunnel) will be less compliant. As a consequence of this stiffer retinaculum the pressure in the carpal tunnel will rise more quickly in stiff patients resulting in CTS-complaints.

A relation between connective tissue composition and joint stiffness is proven. This relationship possibly extends to a relation between stiffness of the skin, joint stiffness and the prevalence of CTS.

Condition or Disease Intervention/Treatment Phase

    Study Design

    Study Type:
    Observational
    Anticipated Enrollment :
    40 participants
    Observational Model:
    Case-Control
    Time Perspective:
    Cross-Sectional
    Official Title:
    Correlation of Joint Stiffness and Stiffness of the Skin and the Prevelation of Carpal Tunnel Syndrome (CTS)
    Study Start Date :
    May 1, 2010
    Anticipated Primary Completion Date :
    Nov 1, 2010
    Anticipated Study Completion Date :
    Dec 1, 2010

    Arms and Interventions

    Arm Intervention/Treatment
    Carpal tunnel syndrome

    Patients with carpal tunnel syndrome
    Trigger finger

    Patients with trigger fingers
    Dupuytren Contracture

    Patients with Dupuytren
    Trauma to the hand

    Patients with an acute trauma to the hand

    Outcome Measures

    Primary Outcome Measures

    1. Joint stiffness [In the 1st month]

      The active range of motion (elbow, wrist, knee and ankle) is measured with a standard goniometer.

    2. Stiffness of the skin [in the 1st month]

      Skinstiffness is measured with a suction cup

    Secondary Outcome Measures

    1. Physical activities [In the 1st month]

      Boston Questionairre

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years to 60 Years
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    Yes
    Inclusion Criteria:

    • Caucasian

    • Carpal tunnel release OR Trigger finger OR Dupuytren OR an acute trauma to the hand

    Exclusion Criteria:

    • Hypo-/hyperthyroidism

    • Diabetes

    • Arthritis

    • Pregnancy

    • Obesity (BMI >30)

    • Anatomical anomalies

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 St Antonius Hospital Nieuwegein Utrecht Netherlands 3430EM

    Sponsors and Collaborators

    • St. Antonius Hospital

    Investigators

    • Principal Investigator: A.B. Mink van der Molen, dr., St. Antonius Hospital

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    , ,
    ClinicalTrials.gov Identifier:
    NCT01081860
    Other Study ID Numbers:
    • STIF CTS
    First Posted:
    Mar 5, 2010
    Last Update Posted:
    Apr 27, 2010
    Last Verified:
    Apr 1, 2010
    Keywords provided by , ,
    Carpal tunnel syndrome
    CTS
    Skinstiffness
    Jointstiffness
    Additional relevant MeSH terms:
    Carpal Tunnel Syndrome
    Syndrome

    Study Results

    No Results Posted as of Apr 27, 2010