Ped-Urolithia: Stone Disease of the Urinary Tract in Children: Clinical Presentation, Diagnostic Methods, Therapeutic Management, Evolution and Prognosis

Sponsor

University Hospital, Strasbourg, France (Other)

Overall Status

Recruiting

CT.gov ID

NCT06032364

Collaborator

(none)

140

Enrollment

Location

Anticipated Duration (Months)

11.6

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The incidence of stone disease of the urinary tract in children is increasingly increasing with a remarkable economic impact for its management.

This incidence is variable according to race, geographic region, socio-economic status and dietary habits.

Oxalo-calcium stones are the most common but the biochemical nature of urinary stones varies depending on the region where those of a phosphatic nature are characterized by a higher incidence in Europe.

The diagnosis is confirmed by imaging. The unprepared abdomen (ASP) has low diagnostic accuracy. The scanner is the reference tool but remains an irradiating examination.

Risk factors for disease recurrence include primarily the presence of an underlying urinary metabolic abnormality and young age. Urinary metabolic abnormalities vary from one study to another.

The understanding of lithogenesis, its evaluation as well as the therapeutic options is essential for adequate and adapted management in the pediatric population.

Condition or Disease	Intervention/Treatment	Phase
Urinary Lithiasis

Study Design

Study Type:

Observational

Anticipated Enrollment :

140 participants

Observational Model:

Case-Only

Time Perspective:

Retrospective

Official Title:

Stone Disease of the Urinary Tract in Children: Clinical Presentation, Diagnostic Methods, Therapeutic Management, Evolution and Prognosis

Actual Study Start Date :

Aug 23, 2023

Anticipated Primary Completion Date :

Aug 23, 2024

Anticipated Study Completion Date :

Aug 23, 2024

Outcome Measures

Primary Outcome Measures

Study of the modalities of the therapeutic management of children with urinary stones, retrospective description of the evolutionary aspects and the risk factors associated with recurrence. [Files analysed retrospectively from January 01, 2010 to December 31, 2022 will be examined]
This study is retrospective on already existing data

Eligibility Criteria

Criteria

Ages Eligible for Study:

1 Year to 17 Years

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion criteria:

Patients aged less than 18 years.
Both sexes.
Subjects presenting with lithiasis of the urinary tree in one of the two departments concerned between 01/01/2010 and 12/31/2022
Subject not opposing, after information, the reuse of their data for the purposes of this research.
Holders of parental authority who do not object, after being informed, to the reuse of their child's data for the purposes of this research.