ESTRIE-TC: Stress Echocardiography Versus Coronary Angiography for Left Main Stenosis Detection

Sponsor

Université de Sherbrooke (Other)

Overall Status

Withdrawn

CT.gov ID

NCT01620320

Collaborator

(none)

Enrollment

Location

Duration (Months)

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Left main stenosis use to be treated by bypass but with the improvement of angioplasty techniques, an increasing number of patients are submit to left main coronary angioplasty. Consequences of left main intra stent stenosis can be disastrous yet, for the moment, no precise recommendation concerning the follow up of these patients exist. The investigators ought to determine if stress echocardiography can predict left main intra stent stenosis as well (non inferiorly)as control angiography that use to be done.

Condition or Disease	Intervention/Treatment	Phase
Left Main Coronary Artery Disease Stenosis	Other: Stress echocardiography

Detailed Description

All patients of the study will pass coronary angiogram and stress echocardiography (treadmill of dobutamine).

Study Design

Study Type:

Observational

Actual Enrollment :

0 participants

Observational Model:

Cohort

Time Perspective:

Prospective

Official Title:

Évaluation de l'Echographie de Stress Par Comparaison à la Coronarographie Comme Outil Non Invasif de détection de la resténose Intra endoprothèse du Tronc Commun

Study Start Date :

Jul 1, 2010

Anticipated Primary Completion Date :

Jul 1, 2012

Anticipated Study Completion Date :

Jul 1, 2013

Arms and Interventions

Arm	Intervention/Treatment
Stress echography Nine to twelve months after their left main angioplasty, patients will go through a stress echo and then the usual control angiography (done routinely in most patient in our center). Patients will act as their own control.	Other: Stress echocardiography Patients able to exercise will have a treadmill test + echography; the others will have a dobutamine echography. Other Names: Dobutamine echocardiography Treadmill echocardiography

Arm

Intervention/Treatment

Stress echography

Nine to twelve months after their left main angioplasty, patients will go through a stress echo and then the usual control angiography (done routinely in most patient in our center). Patients will act as their own control.

Other: Stress echocardiography

Patients able to exercise will have a treadmill test + echography; the others will have a dobutamine echography.

Other Names:

Dobutamine echocardiography

Treadmill echocardiography

Outcome Measures

Primary Outcome Measures

Correlation between stress echocardiography results for the detection of left main prosthesis stenosis with coronary angiogram results. [9 to 12 months after left main angioplasty]

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria:

patients over 18 years old able to give consent and having had left main angioplasty.

Exclusion Criteria:

Bypass on the left anterior descending coronary artery or left circumflex (" protected left main ")
Treating physician judge that angiography need to be done straightaway
Follow up elsewhere than the CHUS
Patient refusal
Pregnant women
Stress echo contraindication(Severe high blood pressure or malignant arrhythmia)or condition that limits interpretation (Left bundle branch block or pacemaker rhythm)