Error-enhanced Learning & Recovery in 2 & 3 Dimensions
Study Details
Study Description
Brief Summary
This study is being done to see how errors lead to improvement. Specifically, we are evaluating the errors stroke participants make during an upper extremity exercise program when reaching for a target using their affected arm. Once we understand the participant's reaching errors, we plan to create a customized reaching exercise according to the individual's specific error tendencies which will lead to better performance on movement ability after training.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Early Phase 1 |
Detailed Description
The neuroplasticity of motor re-learning is a key pathway for recovery in neurorehabilitation. One critical challenge to devising treatment plans for motor recovery is the wide variation that exists between individuals, across movement repetitions, and even within movements. Development of a learning model that looks at these factors would better relate diagnoses to treatments, providing personalization and efficiency to therapy. This proposal aims to advance rehabilitation by building a modeling framework that explores the trends and exploits a fundamental learning process - error.
We are using research lab equipment at the Shirley Ryan AbilityLab (SRALab) Hospital's Robotics group. The equipment will be used to implement the reaching exercises and measure participant movement. The equipment includes:
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Barret b.u.r.t. arm robot with Teneo forearm attachment
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LookinGlass display system
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LeapTM Sensor tracking tool
Day 1: Participants will undergo a screening and consenting session with a research therapist to assess enrollment eligibility.
Day2: If the participant meets all inclusion/exclusion criteria, they will return and complete a series of upper extremity outcome measures to characterize impairment level.
Day 3 and 4: The participant will then complete 1-2 intervention sessions using the Barret b.u.r.t. arm, LookinGlass display screen, and LeapTM tracking sensor. This intervention study will last anywhere from 15-min-90 min depending the equipment functioning. The intervention will consist of two phases:
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Learning Phase to determine the individual's error likelihood
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Training Phase to apply determined error likelihood to see if there are any changes in performance
Our goal is to preliminarily test the direct effect of this new treatment in preparation for the randomized controlled study to come. Understanding how error leads to better performance will help us program future devices for therapy for optimal outcomes.
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Experimental: Stroke Participants Single intervention session |
Other: customized reaching exercise
Learning Phase: approximately 15 minutes of a reaching exercise to determine the individual's movement error likelihood
Training Phase: approximately 45 minutes of a reaching exercise with a customized model applied that is based upon the participants movement error likelihood.
|
Outcome Measures
Primary Outcome Measures
- Movement errors [60-90 minutes]
The frequency of errors made during a reaching exercise
Eligibility Criteria
Criteria
Inclusion Criteria:
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Chronic stroke (at least 8 months post stroke)
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Available medical records and radiographic information about lesion locations
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Hemiparesis
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Some degree of both shoulder and elbow movement
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A "moderate" impairment of arm function (Fugl-Meyer score between 15-50)
Exclusion Criteria:
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Bilateral paresis
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Severe tactile deficits using the Two-Point Discrimination Test
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Severe Spasticity preventing movement
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Aphasia, cognitive impairment, or affective dysfunction that would influence ability to perform the experiment
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Inability to provide informed consent
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Severe current medical problems
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Diffuse/multiple lesion sites or multiple stroke events
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Hemispatial neglect or visual field cut that would prevent subjects from seeing the targets
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Individuals under the age of 21 will no be included since this study is focused on motor behavior and learning of fully developed nervous system
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Inability to attain and maintain testing positions
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Botox injection to the affected upper extremity within the previous 4 months
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Concurrent participation in upper extremity rehabilitation either as part of a research study intervention protocol or a prescribed therapy
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Participation in previous, similar robotics intervention study
None of the following special populations will be included in this research study:
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Adults unable to consent
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Individuals who are not yet adults (infants, children, teenagers)
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Pregnant women
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Prisoners
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Vulnerable Populations
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Shirley Ryan AbilityLab | Chicago | Illinois | United States | 60611 |
| 2 | Shirley Ryan AbilityLab | Chicago | Illinois | United States | 60611 |
Sponsors and Collaborators
- Shirley Ryan AbilityLab
Investigators
- Principal Investigator: James Patton, PhD, Shirley Ryan AbilityLab
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- STU00215000