Action Observation Treatment on Motor Function in Upper Limb of Patients With Chronic Stroke

Sponsor
Riphah International University (Other)
Overall Status
Completed
CT.gov ID
NCT05084820
Collaborator
(none)
14
1
2
10
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Study Details

Study Description

Brief Summary

To determine the effects of action observation treatment on motor functions in upper limb of patients with chronic stroke

Condition or Disease Intervention/Treatment Phase
  • Combination Product: Action observation treatment
  • Combination Product: conventional treatment
N/A

Detailed Description

Stroke is one of the major cause of death in Pakistan and also a prime source of disability in older adults.Mirror neuron system depends on motor regions, and its dominant aspect is that,it is activated for implementation of motor activity and also for its observation. This "dual activation" characteristic of mirror neuron helps in improving the observation and execution of different actions.

aim of this study is to determine the effects of action observation treatment on motor function in upper limb of patients with chronic stroke.

An RCT will be conducted on 14 chronic stroke patients from Omar Hospital and Riphah Rehabilitation Centre Lahore. Patients will be randomly allocated into control group (n=7) and Experimental group (n=7) by lottery method. Control group will be given only conventional treatment that included stretching, strengthening, pinching, gripping, reaching and grasping exercises, while Experimental group received conventional treatment and action observation treatment 3 days/ week for 4 weeks. Treatment outcomes will be assessed on Modified Barthel Index and Fugl-Meyer Assessment for upper extremity (FMA-UE)

Study Design

Study Type:
Interventional
Actual Enrollment :
14 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Intervention Model Description:
each participant will be requested to draw either number one or two from a box.number one refers to group A and number two refers to group B. Group A patients will receive conventional treatment of 40 minutes in total. group B is experimental group , patients will watch videos of 5 common motor tasks that implicit the usage of items to be used for action observation treatment.each participant will be requested to draw either number one or two from a box.number one refers to group A and number two refers to group B. Group A patients will receive conventional treatment of 40 minutes in total. group B is experimental group , patients will watch videos of 5 common motor tasks that implicit the usage of items to be used for action observation treatment.
Masking:
Single (Outcomes Assessor)
Primary Purpose:
Treatment
Official Title:
Effects of Action Observation Treatment on Motor Function in Upper Limb of Patients With Chronic Stroke
Actual Study Start Date :
Oct 15, 2020
Actual Primary Completion Date :
Jul 15, 2021
Actual Study Completion Date :
Aug 15, 2021

Arms and Interventions

Arm Intervention/Treatment
Experimental: Action observation treatment

Action observation treatment

Combination Product: Action observation treatment
Participants will watch 5 videos of motor tasks; each video is of 30 sec and watch for 4 times (i.e. for 2 minutes). Then patient will execute the motor act, soon after the observation with an affected limb for 2 minutes, with total rest time of 5 minutes for this treatment. Conventional treatment of muscle stretching, strengthening and ROM exercises will be given for 15 minutes including rest. Total treatment time is 40 minutes.

Active Comparator: conventional treatment

conventional treatment

Combination Product: conventional treatment
conventional treatment of 40 minutes in total will be performed including Stretching (for 8-10 sec with set of 5 repetitions/ session on each side for 3 minutes total with rest), strengthening (weighted bicep curls, side arm raise and open arm movement exercises with set of 5 repetitions/ session for 9 minutes total with rest), Range of motion exercises active and passive with set of 5 repetitions/ session for 3 minutes total with rest and gripping,reaching, grasping exercises (on each side for total 25 minutes including rest) with assistance of physiotherapist

Outcome Measures

Primary Outcome Measures

  1. modified barthal index [40 minutes]

    The Modified Barthel Index score was used for practical evaluation in activities of daily living. The MBI comprises of 10 items, 6 out of 10 items scored from 0-2 points, 2 items scored from 0-3 points and other 2 items scored from 0-3 points, giving a highest total score of 20 points.

  2. Fugl-Meyer Assessment test [40 minutes]

    Fugl-Meyer Assessment test for Upper extermity.to assess level of motor impairment and its recovery after treatment. The FMA-UE comprises of 7 times.

Eligibility Criteria

Criteria

Ages Eligible for Study:
50 Years to 70 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
  • Chronic Stroke patients (with more than 6 months- 4 years) illness

  • Patients that were able to communicate and comprehend oral instructions

  • Patients with Mini Mental State Examination (MMSE) score more than 24

Exclusion Criteria:
  • Patients having psychiatric histories.

  • Visual and hearing impaired patients

  • Patients with speech impairment

  • Patients with arthritic deformities in upper limb (with or without using assistive device)

  • Patients with diagnosed mental illness.

Contacts and Locations

Locations

Site City State Country Postal Code
1 Riphah international university Islamabad Fedral Pakistan 44000

Sponsors and Collaborators

  • Riphah International University

Investigators

  • Principal Investigator: zeest hashmi, MS NMPT, Riphah International University

Study Documents (Full-Text)

None provided.

More Information

Publications

Responsible Party:
Riphah International University
ClinicalTrials.gov Identifier:
NCT05084820
Other Study ID Numbers:
  • REC/Lhr/20/0213 Hira Rehman
First Posted:
Oct 20, 2021
Last Update Posted:
Oct 20, 2021
Last Verified:
Oct 1, 2021
Individual Participant Data (IPD) Sharing Statement:
No
Plan to Share IPD:
No
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Keywords provided by Riphah International University
Additional relevant MeSH terms:

Study Results

No Results Posted as of Oct 20, 2021