IRMA2: Evaluation of New Diagnostic Methods of Cardio-embolic Related (Atrial Fibrillation) Cerebral Infarction
Study Details
Study Description
Brief Summary
The aim of the study is to estimate the contribution of abdominal imaging by magnetic resonance Imaging (MRI) and abdominal scanner in the detection of subdiaphragmatic infarction associated to the atrial fibrillation in the cerebral infarction.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
N/A |
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Experimental: Stroke
|
Procedure: MRI
Procedure: Abdominal scanner
|
Outcome Measures
Primary Outcome Measures
- Number of patients with subdiaphragmatic infarctions detected by abdominal MRI [14 days]
Secondary Outcome Measures
- Number of patients with subdiaphragmatic infarctions detected by abdominal scanner [14 days]
Eligibility Criteria
Criteria
Inclusion Criteria:
-
Patient over 18
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Patient having a CHADS-VAsc Score ≥ 2;
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Patient hospitalized for a secondary established ischemic accident in an atrial fibrillation not anticoagulated (INR<2 and/or receiving antiplatelet (aspirin, clopidogrel)) for less than 14 days;
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Patient affiliated to a national insurance scheme or beneficiary
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Patient having given a written consent
Exclusion Criteria:
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Patient presenting cognitive disorders incompatible with the planned examinations (MRI / SCANNER).
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Pacemaker or implantable defibrillator, or other contraindication in the MRI (metallic eye brightness, intra cerebral clip).
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Contraindication in injected scanner.
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Current pregnancy
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Hôpital Foch | Suresnes | France | 92150 |
Sponsors and Collaborators
- Hopital Foch
Investigators
- Principal Investigator: Bertrand Lapergue, MD, Hôpital Foch
Study Documents (Full-Text)
None provided.More Information
Publications
- Abboud H, Labreuche J, Gongora-Riverra F, Jaramillo A, Duyckaerts C, Steg PG, Hauw JJ, Amarenco P. Prevalence and determinants of subdiaphragmatic visceral infarction in patients with fatal stroke. Stroke. 2007 May;38(5):1442-6. Epub 2007 Mar 22.
- Flint AC, Tayal AH. The search for paroxysmal atrial fibrillation in cryptogenic stroke: leave no stone unturned. Neurology. 2013 Apr 23;80(17):1542-3. doi: 10.1212/WNL.0b013e31828f1938. Epub 2013 Mar 27.
- Slaoui T, Klein IF, Guidoux C, Cabrejo L, Meseguer E, Abboud H, Lavalllée PC, Mazighi M, Labreuche J, Amarenco P. Prevalence of subdiaphragmatic visceral infarction in cardioembolic stroke. Neurology. 2010 Mar 30;74(13):1030-2. doi: 10.1212/WNL.0b013e3181d76aaa. Epub 2010 Mar 3.
- White H, Boden-Albala B, Wang C, Elkind MS, Rundek T, Wright CB, Sacco RL. Ischemic stroke subtype incidence among whites, blacks, and Hispanics: the Northern Manhattan Study. Circulation. 2005 Mar 15;111(10):1327-31.
- 2016/02
- 2016-A00020-51