The Role of Auditory Feedback in Guiding Upper Extremity Movements

Sponsor

Sunnybrook Health Sciences Centre (Other)

Overall Status

Unknown status

CT.gov ID

NCT02100306

Collaborator

(none)

Enrollment

Location

Arm

Duration (Months)

1.6

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Stroke is one of the leading causes of disability, with an estimated prevalence of 50,000 cases per year in Canada. Less than half of stroke patients regain use of their arm and hand. There is currently no intervention regime that is the gold standard, despite the variety of therapeutic techniques used to treat the upper extremity post-stroke. The use of external feedback to improve motor learning is a technique that has been less studied but shows promise. Therefore, the purpose of this proof of principle study it to test whether different auditory feedback frequencies can facilitate reaching ability in people with stroke. In addition brain scans will be collected that will enable us to determine how stroke severity may impact on one's ability to improve with this technique.

We hypothesize that patients who receive less feedback (50% alternate) will have enhanced learning relative to the patients who receive more feedback (100%).

Condition or Disease	Intervention/Treatment	Phase
Stroke	Behavioral: Auditory Feedback 100% Behavioral: Auditory Feedback 50% alternate	N/A

Study Design

Study Type:

Interventional

Anticipated Enrollment :

26 participants

Allocation:

N/A

Intervention Model:

Single Group Assignment

Masking:

None (Open Label)

Primary Purpose:

Basic Science

Study Start Date :

May 1, 2014

Anticipated Primary Completion Date :

Sep 1, 2015

Anticipated Study Completion Date :

Sep 1, 2015

Arms and Interventions

Arm	Intervention/Treatment
Experimental: Patients Patients will receive: Auditory Feedback 100% Auditory Feedback 50% alternate	Behavioral: Auditory Feedback 100% Patients will receive constant auditory feedback across training trials. Behavioral: Auditory Feedback 50% alternate Patients will receive alternating auditory feedback (1 trial auditory feedback; 1 trial no auditory feedback) across trials

Arm

Intervention/Treatment

Experimental: Patients

Patients will receive: Auditory Feedback 100% Auditory Feedback 50% alternate

Behavioral: Auditory Feedback 100%

Patients will receive constant auditory feedback across training trials.

Behavioral: Auditory Feedback 50% alternate

Patients will receive alternating auditory feedback (1 trial auditory feedback; 1 trial no auditory feedback) across trials

Outcome Measures

Primary Outcome Measures

Change in movement error from baseline [participants will be followed for the duration of the study, an expected 3 hours per day for 2 weeks (5 days per week/10 days total)]

Secondary Outcome Measures

Change in range of motion [participants will be followed for the duration of the study, an expected 3 hours per day for 2 weeks (5 days per week/10 days total)]
Change in movement duration [participants will be followed for the duration of the study, an expected 3 hours per day for 2 weeks (5 days per week/10 days total)]

Eligibility Criteria

Criteria

Ages Eligible for Study:

30 Years to 85 Years

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Yes

Inclusion Criteria:

Unilateral first time MCA ischemic stroke
Stroke patients should have some movement of shoulder/elbow (no movement of hand - e.g. hand, fingers - is OK)
2 months post
between 30-85 years

Exclusion Criteria:

prior stroke
severe comprehension (or cognitive) deficit that compromises informed consent or understanding of instructions
contraindications to MRI (e.g. claustrophobia, metal implants)
neurodegenerative or psychiatric disease
apraxia
auditory deficits that would impair testing
prior musculoskeletal injury to back or upper extremity (including shoulder subluxation from stroke)
skin conditions that would preclude taping of goniometers

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Sunnybrook Health Sciences Centre	Toronto	Ontario	Canada	M4N 3M5

Sponsors and Collaborators

Sunnybrook Health Sciences Centre

Investigators

Principal Investigator: Joyce Chen, PhD, Canadian Partnership for Stroke Recovery

Study Documents (Full-Text)

None provided.

More Information

Additional Information:

Related Info

Publications

None provided.

Responsible Party:

Sunnybrook Health Sciences Centre

ClinicalTrials.gov Identifier:

NCT02100306

Other Study ID Numbers:

JCH-1234-SF

First Posted:

Mar 31, 2014

Last Update Posted:

Mar 31, 2014

Last Verified:

Mar 1, 2014

Study Results

No Results Posted as of Mar 31, 2014