Working Memory Training in Adults With Substance Abuse and Executive Function Deficits.
Study Details
Study Description
Brief Summary
The purpose of this study is to evaluate the effects of a computerized working memory training program on substance abuse, psychosocial functioning, cognitive performance and psychiatric problems in adults with substance abuse and attention problems.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Phase 2 |
Detailed Description
The primary aim of this study is to examine the effects of 5 weeks of computerized working memory training on substance abuse. Secondary aims are to explore whether effects are mediated by changes in executive functions and/or moderated by personality. Also, effects on measures of psychosocial functioning, depression, anxiety and attention will be explored. Follow-up assessment will be conducted at 6 months post training.
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Experimental: Cogmed working memory training 30-40 minutes of Cogmed computerized working memory training 3-5 days a week for 5-8 weeks. Every training session consists of a set of visual- and verbal working memory tasks that are trained on during the session. |
Behavioral: Computerized Cogmed working memory training
Computerized working memory training with Cogmed QM software. The QM software consists of a set of verbal and visual working memory tasks which is trained for 25-40 minutes each session.
|
| Active Comparator: Treatment as usual Treatment as usual can consist of medication, psychotherapy, counseling, and psychological assessment. After a 8 week period participants in this arm well be offered Cogmed working memory training. |
Behavioral: Treatment as usual
Treatment as usual can consist of medication, psychotherapy, counseling, and psychological assessment.
|
Outcome Measures
Primary Outcome Measures
- Change from baseline in substance abuse measured with Substance abuse scales in Adult Self Report (ASR; ASEBA). [Baseline and at 25 weeks]
Secondary Outcome Measures
- Change from baseline in Adult Self Report (ASR; ASEBA) Attention problems scale. [Baseline and at 25 weeks]
- Change from baseline in Adult Self Report (ASR; ASEBA) Internalizing index. [Baseline and at 25 weeks]
- Change from baseline in Adult Self Report (ASR; ASEBA) Externalizing index. [Baseline and at 25 weeks]
- Change from baseline in Adult Self Report (ASR; ASEBA) Adaptive functioning scales. [Baseline and at 25 weeks]
- Change from baseline in Executive functioning measured with Behavior Rating Inventory of Executive Function-Adult (BRIEF-A). [Baseline and at 25 weeks]
- Change from baseline in verbal working memory measured with performance on Digit span. [Baseline and at 25 weeks]
- Change from baseline in visual working memory measured with performance on Span board. [Baseline and at 25 weeks]
- Change from baseline in focused attention measured with performance on Conners Continuous Performance Test-II (CCPT-II). [Baseline and at 25 weeks]
- Change from baseline in vigilance measured with performance on Conners Continuous Performance Test-II (CCPT-II). [Baseline and at 25 weeks]
- Change from baseline in reading speed measured with performance on Reading speed in Diagnostic Reading and Writing Test (DLS; Swedish version). [Baseline and at 25 weeks]
Eligibility Criteria
Criteria
Inclusion Criteria:
- Treatment seeking adults with substance abuse and executive function deficits.
Exclusion Criteria:
-
Acute intoxication or abstinence symptoms of any substance.
-
Psychosis.
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Psychiatric Research Centre | Örebro | Sweden | 701 16 |
Sponsors and Collaborators
- Örebro Läns Landsting
Investigators
- Study Director: Lars Kjellin, Docent, Örebro Läns Landsting
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- RA02