The Influence of Caffeine Supplementation on Specific Performance and Training Activities

Sponsor

Poznan University of Life Sciences (Other)

Overall Status

Suspended

CT.gov ID

NCT03822663

Collaborator

Poznan University of Physical Education (Other)

Enrollment

Location

Arms

45.5

Anticipated Duration (Months)

1.1

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The purpose of this study is to verify the effect of acute caffeine (CAF) and placebo (PLA) supplementation on physical capacity and discipline-specific exercise performance in athletes, in a randomised, double-blind, placebo-controlled crossover trial.

Condition or Disease	Intervention/Treatment	Phase
Supplementation Sports	Dietary Supplement: Caffeine supplementation Dietary Supplement: Placebo treatment	Phase 3

Detailed Description

Caffeine (CAF) is often proposed as an ergogenic agent, especially during high-intensity efforts. CAF supplementation may reduce effort-induced multi-faceted symptoms of fatigue and can improve psychomotor functions (like agility or decision-making processes), which is required during the intermittent high-intensity efforts in combat sports and speed-strength disciplines. Moreover, it is suggested that CAF treatment is associated with increased glycolytic activity during simulated or real training/competition bouts, which results in performance and physical capacity improvement.

However, there are hardly any data on the individual CAF-induced and dose-dependent changes in physical capacity and discipline-specific performance in combat sports and speed-strength disciplines. Therefore, the study aims to examine the effect of acute, different-dose CAF ingestion on physical capacity and discipline-specific performance in combat sports and speed-strength athletes, in a randomized, double-blind, placebo-controlled crossover trial.

Study Design

Study Type:

Interventional

Anticipated Enrollment :

50 participants

Allocation:

Randomized

Intervention Model:

Crossover Assignment

Masking:

Triple (Participant, Investigator, Outcomes Assessor)

Primary Purpose:

Treatment

Official Title:

The Influence of Caffeine Supplementation on Discipline-Specific Performance and Training Activities in Combat Sports and Speed-Strength Disciplines

Actual Study Start Date :

May 15, 2017

Anticipated Primary Completion Date :

Feb 1, 2021

Anticipated Study Completion Date :

Mar 1, 2021

Arms and Interventions

Arm	Intervention/Treatment
Experimental: Caffeine supplementation Group taking oral CAF (Caffeine) supplementation in a different-dose crossover regimen.	Dietary Supplement: Caffeine supplementation The experimental procedure for each athlete includes an acute CAF supplementation in a different-dose crossover regimen in order to assess whether the dose affects the actual physical capacity and discipline-specific exercise performance (doses: 3.0-, 6.0- and 9.0 mg/kg of body mass, respectively). CAF (pure pharmaceutical caffeine) will be administered in the dissolved form. On testing days, the supplements will be taken 45 min before physical and exercise capacity test session. Between the CAF and PLA or a PLA and CAF treatments, a minimum 7-day washout period will be introduced.
Placebo Comparator: Placebo treatment Group taking oral supplementation with placebo.	Dietary Supplement: Placebo treatment The experimental procedure for each athlete will include PLA supplementation. Placebo will be administered in the dissolved form. On testing days, the PLA will be taken 45 min before physical and exercise capacity test session. Between the PLA and CAF or a CAF and PLA treatments, a minimum 7-day washout period will be introduced.

Arm

Intervention/Treatment

Experimental: Caffeine supplementation

Group taking oral CAF (Caffeine) supplementation in a different-dose crossover regimen.

Dietary Supplement: Caffeine supplementation

The experimental procedure for each athlete includes an acute CAF supplementation in a different-dose crossover regimen in order to assess whether the dose affects the actual physical capacity and discipline-specific exercise performance (doses: 3.0-, 6.0- and 9.0 mg/kg of body mass, respectively). CAF (pure pharmaceutical caffeine) will be administered in the dissolved form. On testing days, the supplements will be taken 45 min before physical and exercise capacity test session. Between the CAF and PLA or a PLA and CAF treatments, a minimum 7-day washout period will be introduced.

Placebo Comparator: Placebo treatment

Group taking oral supplementation with placebo.

Dietary Supplement: Placebo treatment

The experimental procedure for each athlete will include PLA supplementation. Placebo will be administered in the dissolved form. On testing days, the PLA will be taken 45 min before physical and exercise capacity test session. Between the PLA and CAF or a CAF and PLA treatments, a minimum 7-day washout period will be introduced.

Outcome Measures

Primary Outcome Measures

Changes in discipline-specific exercise capacity after caffeine supplementation and placebo treatment [Baseline and during 1 day of acute CAF and PLA supplementation]
Assessment of the discipline-specific exercise capacity tests carried out at baseline, and after CAF and PLA supplementation

Secondary Outcome Measures

Changes in sports training / competition activities after discipline-specific exercise tests [Baseline and during 1 day of acute CAF and PLA supplementation]
Assessment of the sports training / competition activities after discipline-specific exercise tests carried out at baseline, and after CAF and PLA supplementation
Changes in rate of perceived exertion after discipline-specific exercise tests [Baseline and during 1 day of acute CAF and PLA supplementation]
Assessment of the Borg Rating of Perceived Exertion (RPE) scale after discipline-specific exercise tests carried out at baseline, and after CAF and PLA supplementation
Changes in heart rate during discipline-specific exercise tests [Baseline and during 1 day of acute CAF and PLA supplementation]
Assessment of the Heart Rate during and after discipline-specific exercise tests carried out at baseline, and after CAF and PLA supplementation

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years to 40 Years

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Yes

Inclusion Criteria:

written consent to participate,
a current medical clearance to practice sports,
training experience: at least 2 years,
minimum of 4 workout sessions (in the discipline covered by the study) a week.

Exclusion Criteria:

current injury,
any health-related contraindication,
declared general feeling of being unwell,
unwilling to follow the study protocol.

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Poznan University of Life Sciences, ul.Wojska Polskiego 31	Poznań	Wielkopolska	Poland	60-624

Sponsors and Collaborators

Poznan University of Life Sciences
Poznan University of Physical Education

Investigators

Principal Investigator: Krzysztof Durkalec-Michalski, PhD, Poznan University of Life Sciences

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

Responsible Party:

Krzysztof Durkalec-Michalski, PhD, Principal Investigator, Poznan University of Life Sciences

ClinicalTrials.gov Identifier:

NCT03822663

Other Study ID Numbers:

ULS00007

First Posted:

Jan 30, 2019

Last Update Posted:

Apr 10, 2020

Last Verified:

Apr 1, 2020

Individual Participant Data (IPD) Sharing Statement:

Undecided

Plan to Share IPD:

Undecided

Studies a U.S. FDA-regulated Drug Product:

Studies a U.S. FDA-regulated Device Product:

Keywords provided by Krzysztof Durkalec-Michalski, PhD, Principal Investigator, Poznan University of Life Sciences

Additional relevant MeSH terms:

Caffeine

Study Results

No Results Posted as of Apr 10, 2020