Temperature and Mortality

Sponsor

Chinese Academy of Sciences (Other)

Overall Status

Completed

CT.gov ID

NCT03259100

Collaborator

(none)

17,000,000

Enrollment

Actual Duration (Months)

Study Details

Study Description

Brief Summary

The investigators evaluated the spatial association between, cardiovascular diseases (CVD) and stroke mortality rate with average ambient temperature (Ta) , and then used this relationship to model future temporal trends in mortality from CVD and stroke till the end of century (2099) using different warming scenarios across the mainland USA.

Condition or Disease	Intervention/Treatment	Phase
Cardiovascular Diseases	Other: all the data collection have done by CDC.

Detailed Description

the investigators used data on mortality rate (per 100,000 individuals) for CVD and stroke (between 2011 and 2013, age>35years) from the publicly available Centers for disease prevention and control (CDC) web site (www.cdc.gov). CVD mortality was defined as the number of deaths per 100,000 personyears due to circulatory causes (International Statistical Classification of Diseases, Tenth Revision, codes I00-I99).Oak Ridge National laboratory was the source of the ambient temperature data (http://www.daac.ornl.gov: files B01, B02 and C07).The investigators obtained data on prevalence of HTN (HTN was defined as systolic blood pressure (BP) of at least 140 mm Hg, self-reported use of antihypertensive treatment, or both) from county health rankings and roadmaps organisation (www.countyhealthrankings.org), which were estimated based on National Health and Nutrition Examination Survey in five two-year waves from 1999-2008 including 26,349 adults aged 30 years and older and from the Behavioral Risk Factor Surveillance System (BRFSS) from 1997-2009 including 1,283,722 adults aged 30 years and older.

Study Design

Study Type:

Observational

Actual Enrollment :

17000000 participants

Observational Model:

Ecologic or Community

Time Perspective:

Retrospective

Official Title:

Impact of Increasing Temperature Over the Coming Century on Mortality From CVD and Stroke

Actual Study Start Date :

Jan 1, 2011

Actual Primary Completion Date :

Jan 1, 2012

Actual Study Completion Date :

Feb 1, 2013

Outcome Measures

Primary Outcome Measures

spatial association between, cardiovascular diseases (CVD) and stroke mortality rate with average ambient temperature [2011-2013]
spatial association between, cardiovascular diseases (CVD) and stroke mortality rate with average ambient temperature

Eligibility Criteria

Criteria

Ages Eligible for Study:

35 Years and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria:

age>35 years

Exclusion Criteria:

None

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

Chinese Academy of Sciences

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Additional Information:

CDC website

Publications

Mazidi M, Speakman JR. Ambient particulate air pollution (PM2.5) is associated with the ratio of type 2 diabetes to obesity. Sci Rep. 2017 Aug 22;7(1):9144. doi: 10.1038/s41598-017-08287-1.

Responsible Party:

John Speakman, Principal Investigator, Chinese Academy of Sciences

ClinicalTrials.gov Identifier:

NCT03259100

Other Study ID Numbers:

CDC and IPCC

First Posted:

Aug 23, 2017

Last Update Posted:

Aug 24, 2017

Last Verified:

Aug 1, 2017

Individual Participant Data (IPD) Sharing Statement:

Yes

Plan to Share IPD:

Yes

Studies a U.S. FDA-regulated Drug Product:

Studies a U.S. FDA-regulated Device Product:

Additional relevant MeSH terms:

Cardiovascular Diseases

Study Results

No Results Posted as of Aug 24, 2017