Thyroid Hormone Values and Anti-thyroid Peroxidase Antibody Positivity in Recurrent Pregnancy Loss
Sponsor
Zonguldak Bulent Ecevit University (Other)
Overall Status
Completed
CT.gov ID
NCT05680376
Collaborator
(none)
103
1
57
1.8
Study Details
Study Description
Brief Summary
The aim of this study is to compare the thyroid hormone values and anti-thyroid peroxidase (anti-TPO) levels of women with a diagnosis of recurrent pregnancy loss (RPL) and healthy pregnancies. The primary objective is to find out the relationship between recurrent pregnancy loss with thyroid hormone levels and anti-TPO positivity.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
|
Study Design
Study Type:
Observational
Actual Enrollment
:
103 participants
Observational Model:
Case-Control
Time Perspective:
Retrospective
Official Title:
Relationship Between Habitual Abortion With Thyroid Hormone Values and Anti-TPO (Anti-thyroid Peroxidase Antibody) Positivity
Actual Study Start Date
:
Jan 1, 2018
Actual Primary Completion Date
:
Oct 1, 2022
Actual Study Completion Date
:
Oct 1, 2022
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Recurrent Pregnancy loss patients with a diagnosis of recurrent miscarriage |
|
| Healthy Controls healthy women at same age and similar demographics |
Outcome Measures
Primary Outcome Measures
- Anti-thyroid Peroxidase Antibodies [4 years]
presence of Anti-thyroid Peroxidase Antibodies in both groups
- Thyroid Hormone Levels [4 years]
levels of Thyroid stimulant Hormone, Thyroxin and triiodothyronine levels
Eligibility Criteria
Criteria
Ages Eligible for Study:
18 Years
to 45 Years
Sexes Eligible for Study:
Female
Accepts Healthy Volunteers:
No
Inclusion Criteria:
-
women with 2 or more pregnancy loses
-
for controls women with least one healthy baby
Exclusion Criteria:
-
any other metabolic disease
-
women with one miscarriage
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Zonguldak Bulent Ecevit University Faculty of Medicine | Zonguldak | Turkey |
Sponsors and Collaborators
- Zonguldak Bulent Ecevit University
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
Büşra Özgen Çeviker,
Resident at Family Medicine Department,
Zonguldak Bulent Ecevit University
ClinicalTrials.gov Identifier:
NCT05680376
Other Study ID Numbers:
- 2022/17
First Posted:
Jan 11, 2023
Last Update Posted:
Jan 11, 2023
Last Verified:
Dec 1, 2022
Individual Participant Data (IPD) Sharing Statement:
No
Plan to Share IPD:
No
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Keywords provided by Büşra Özgen Çeviker,
Resident at Family Medicine Department,
Zonguldak Bulent Ecevit University
Additional relevant MeSH terms: