Acute Kidney Injury Among Pediatric Cancer Patients At South Egypt Cancer Institute

Sponsor

Assiut University (Other)

Overall Status

Not yet recruiting

CT.gov ID

NCT06081608

Collaborator

(none)

Enrollment

Anticipated Duration (Months)

Study Details

Study Description

Brief Summary

Cancer is the second most frequent cause of premature death in children. The incidence of pediatric cancer varies by region and country, but it is generally considered rare with an estimated 300,000 new cases diagnosed worldwide. Acute kidney injury in pediatric cancer patients refers to the sudden and often temporary loss of renal function, which can lead to a variety of complications if not treated correctly.

Condition or Disease	Intervention/Treatment	Phase
To Determine the Cumulative Incidence of AKI Using KDIGO Criteria in Pediatric Patients With Malignancy in South Egypt Cancer Institute (SECI)	Diagnostic Test: kidney function test

Detailed Description

Primary: To determine the cumulative incidence of AKI using KDIGO criteria in pediatric patients with malignancy in South Egypt Cancer Institute (SECI)
Secondary:

Incidence of Hospital-acquired and community-acquired AKI
Asses the risk factors of the incidence of AKI
To determine in-hospital outcome (time to in-hospital death, length of hospital stay, and time to kidney recovery) of AKI.

This is a prospective study that will be carried out in the Paediatric Oncology and Haematological Malignancies Department including patients diagnosed with malignant tumours and hospitalized from 1st April 2023 for one year duration.

Study Design

Study Type:

Observational [Patient Registry]

Anticipated Enrollment :

2 participants

Observational Model:

Cohort

Time Perspective:

Prospective

Official Title:

Acute Kidney Injury Among Pediatric Cancer Patients At South Egypt Cancer Institute

Anticipated Study Start Date :

Nov 1, 2023

Anticipated Primary Completion Date :

Apr 1, 2024

Anticipated Study Completion Date :

Sep 1, 2024

Outcome Measures

Primary Outcome Measures

To determine the cumulative incidence of AKI using KDIGO criteria in pediatric patients with malignancy in South Egypt Cancer Institute (SECI) [from November 2023 till November 2024]

Eligibility Criteria

Criteria

Ages Eligible for Study:

30 Days to 18 Years

Sexes Eligible for Study:

All

Inclusion Criteria:

• Children of both sexes (aged from 1 month to 18 years at diagnosis)
Patients with either hematological malignancies or solid tumors admitted to the Paediatric Oncology and Haematological Malignancies Department

Exclusion Criteria:

Children who had an unconfirmed cancer diagnosis.
Children more than 18 years at diagnosis.
Children with preexisting chronic kidney disease (CKD) that defined as the presence of structural or functional kidney damage that persist over minimum of three month
The patient underwent hematopoietic stem cell transplantation. Patients with 1 s.Cr level.
Patient underwent renal transplant.

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

Assiut University

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

Responsible Party:

Ahmed Mohamed Amir Fathy Riad, resident doctor, Assiut University

ClinicalTrials.gov Identifier:

NCT06081608

Other Study ID Numbers:

First Posted:

Oct 13, 2023

Last Update Posted:

Oct 13, 2023

Last Verified:

Oct 1, 2023

Individual Participant Data (IPD) Sharing Statement:

Undecided

Plan to Share IPD:

Undecided

Additional relevant MeSH terms:

Acute Kidney Injury

Study Results

No Results Posted as of Oct 13, 2023