Lung Ultrasound Score and Weaning Outcome

• Sponsor: Cairo University (Other)
• Overall Status: Completed
• CT.gov ID: NCT05289960
• Collaborator: (none)
• Enrollment: 50
• Location: 1
• Arms: 2
• Actual Duration (Months): 14.9
• Patients Per Site Per Month: 3.3

Study Details

Study Description

Brief Summary

Objectives: Failure of extubation of patients on mechanical ventilation is one of the common problems in the ICU.

Aim of work: To evaluate the validity of lung ultrasound score in prediction of weaning outcomes and post-extubation distress.

Condition or Disease	Intervention/Treatment	Phase
Lung Ultrasound Score; Acute Respiratory Failure	Other: lung ultrasound	N/A

Detailed Description

Methods: A prospective observational study of 50 patients planned for extubation who passed a spontaneous breathing trial, lung ultrasound score and serum level of NT-PRO BNP were done to all patients at end of spontaneous breathing trial, and all patients were followed after extubation and monitored for oxygenation, re-intubation rate, ICU stay, and ICU mortality.

Study Design

• Study Type: Interventional
• Actual Enrollment: 50 participants
• Allocation: Non-Randomized
• Intervention Model: Parallel Assignment
• Masking: None (Open Label)
• Primary Purpose: Health Services Research
• Official Title: Lung Ultrasound Score for Prediction of Weaning Outcome
• Actual Study Start Date: Dec 1, 2020
• Actual Primary Completion Date: Feb 28, 2022
• Actual Study Completion Date: Mar 1, 2022

Arms and Interventions

Arm	Intervention/Treatment
Other: patients eligible for weaning by spontaneous breathing trial	Other: lung ultrasound; Lung ultrasound score was done at the end of SBT using curved array ultrasound probe 2-5 MHz, Siemens X300, Korea
Other: non invasive ventilation after weaning	Other: lung ultrasound; Lung ultrasound score was done at the end of SBT using curved array ultrasound probe 2-5 MHz, Siemens X300, Korea

Outcome Measures

Primary Outcome Measures

1. Extubation success [48 hours]

   number of participants that do not need for respiratory support neither NIV nor intubation for one week during ICU stay

Eligibility Criteria

Criteria

• Ages Eligible for Study: 18 Years to 80 Years
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:

• 1. Patients age > 18 years

1. Patients intubated and mechanically ventilated for more than 48 hours in the intensive care unit and planned for extubation.

Exclusion Criteria:

• 1. Patients < or =18 years 2. Patients with left ventricular failure

1. Right ventricular failure

2. Pulmonary hypertension

3. Aortic valve disease

4. Hyperthyroidism

5. Tracheostomy

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Cairo University Hospitals	Cairo		Egypt	11345

Sponsors and Collaborators

• Cairo University

Investigators

• Principal Investigator: farouk faris, MD, Cairo University

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: Mostafa Farouk, lecturer, Cairo University
• ClinicalTrials.gov Identifier: NCT05289960
• Other Study ID Numbers: MS-490-2020
• First Posted: Mar 22, 2022
• Last Update Posted: Apr 1, 2022
• Last Verified: Mar 1, 2022

• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No
• Additional relevant MeSH terms: Respiratory Insufficiency

Study Results

No Results Posted as of Apr 1, 2022