OC and ICTP in Gingival Crevicular Fluid During Piezocision Accelerated Orthodontic Treatment
Study Details
Study Description
Brief Summary
The aim of this study was to evaluate the tooth movement with and without piezocision with regard to the levels of osteocalcin and cross-linked C-terminal telopeptides of type I collagen in the gingival crevicular fluid.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
N/A |
Detailed Description
15 systemically healthy subjects requiring extraction of the maxillary 1. premolars with distalization of the maxillary canines were enrolled to the study. Piezocisions were performed on the distal and mesial sides of the right maxillary canines while the left maxillary canines served as controls. Canine distalization was performed via closed-coil springs applying 150 g of force per side by using miniscrews as anchorage. Gingival crevicular fluid samples were collected from both mesial and distal sides of right and left maxillary canines at 0, 1, 7, 14 and 28 days. The gingival crevicular fluid levels of osteocalcin and cross-linked C-terminal telopeptides of type I collagen were determined by using ELISA. The rate of tooth movement was measured on 14 and 28 days.
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Experimental: Piezocision Piezocision was performed on the mesial and distal side of the maxillary right canine tooth which was served as the piezocision group. Then canine distalization was performed via closed-coil springs applying 150 g of force by using mini-screws as anchorage. |
Procedure: Piezocision
Piezocisions were performed on the mesial and distal sides of the right maxillary canines. Then canine distalization was performed via closed-coil springs applying 150 g of force by using mini-screws as anchorage.
|
| Active Comparator: Control Maxillary left canine served as the control group and canine distalization was performed via closed-coil springs applying 150 g of force by using mini-screws as anchorage. |
Procedure: Control
The mesial and distal sides of the left maxillary canines served as controls and canine distalization was performed via closed-coil springs applying 150 g of force by using mini-screws as anchorage.
|
Outcome Measures
Primary Outcome Measures
- Gingival crevicular fluid osteocalcin level (ng/ml) [28 days after canine distalization]
Gingival crevicular fluid samples were collected from mesial and distal sides of the maxillary right and left canines.The gingival crevicular fluid level of osteocalcin was determined by using ELISA
- Gingival crevicular fluid cross-linked C-terminal telopeptides of type I level (ng/ml) [28 days after canine distalization]
Gingival crevicular fluid samples were collected from mesial and distal sides of the maxillary right and left canines.The gingival crevicular fluid level of cross-linked C-terminal telopeptides of type I collagen was determined by using ELISA.
Secondary Outcome Measures
- The amount of canine movement (mm) [Baseline (day 0) before canine distalization and, 14 and 28 days after canine distalization]
All measurements were performed on the dental cast model using a digital caliper. The amount of space closure was based on the measurements of the distance between the contact points of the distal surface of canine and the mesial surface of second premolar. The change of distance between the three observation periods represented the amount of canine movement.
- Retraction rate (mm/day) of canine movement [14 and 28 days after canine distalization]
All measurements were performed on the dental cast model using a digital caliper. The amount of space closure was based on the measurements of the distance between the contact points of the distal surface of canine and the mesial surface of second premolar. The change of distance between the three observation periods represented the amount of canine movement, which was divided by the number of days between two sessions to obtain the retraction rate on daily basis
Eligibility Criteria
Criteria
Inclusion Criteria:
-
Class I, Class II or Class III malocclusion,
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Proclined incisors requiring extraction of the maxillary first premolars with subsequent retraction of the maxillary canines
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No previous orthodontic treatment
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Good oral hygiene and periodontal health (plaque and gingival indices less or equal 1, probing depth less or equal 3 mm, no radiographic bone loss).
Exclusion Criteria:
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having systemic diseases that could affect bone and tooth movement
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smoking
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Marmara University Faculty of Dentistry | İstanbul | Turkey | 34854 |
Sponsors and Collaborators
- Marmara University
Investigators
- Principal Investigator: Hatice Selin Yıldırım, Dr., Marmara University, Faculty of Dentistry, Department of Peridontology
Study Documents (Full-Text)
None provided.More Information
Publications
- Alfaqeeh SA, Anil S. Osteocalcin and N-telopeptides of type I collagen marker levels in gingival crevicular fluid during different stages of orthodontic tooth movement. Am J Orthod Dentofacial Orthop. 2011 Jun;139(6):e553-9. doi: 10.1016/j.ajodo.2011.03.005.
- Dibart S, Surmenian J, Sebaoun JD, Montesani L. Rapid treatment of Class II malocclusion with piezocision: two case reports. Int J Periodontics Restorative Dent. 2010 Oct;30(5):487-93.
- Raj SC, Praharaj K, Barik AK, Patnaik K, Mahapatra A, Mohanty D, Katti N, Mishra D, Panda SM. Retraction With and Without Piezocision-Facilitated Orthodontics: A Randomized Controlled Trial. Int J Periodontics Restorative Dent. 2020 Jan/Feb;40(1):e19-e26. doi: 10.11607/prd.3968.
- 04.03.2013.38