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TRANSPARK_LONG: The Diagnostic Value of Early Transcranial Ultrasound in Patients With Extrapyramidal Diseases in a Swedish Population

Sponsor
Region Skane (Other)
Overall Status
Not yet recruiting
CT.gov ID
NCT06032585
Collaborator
(none)
80
Enrollment
24
Anticipated Duration (Months)

Study Details

Study Description

Brief Summary

Popular science summary of the project The purpose of the study is to investigate in a Swedish population how well our previous ultrasound findings match the final diagnosis (PD, APS or ET) after a particularly long follow-up time, which greatly increases the certainty that the diagnosis does not change more and is thus correct. We also want to study whether the initial ultrasound findings have changed during the control interval and whether measurement results regarding the diameter in one of the fluid-filled rooms in the brain (third ventricle) can be correlated with the development of cognitive impairment or dementia later in the course of the disease. For this, we have got ethical permission to go into the patients' medical records and to call a subgroup back to the clinic to be able to do a new examination and a memory test.

Condition or Disease Intervention/Treatment Phase

    Study Design

    Study Type:
    Observational
    Anticipated Enrollment :
    80 participants
    Observational Model:
    Case-Only
    Time Perspective:
    Retrospective
    Official Title:
    TRANSPARK_LONG: The Diagnostic Value of Early Transcranial Ultrasound in Patients With Extrapyramidal Diseases in a Swedish Population: an Evaluation in the Form of a Retrospective Cohort Study With a Long Follow-up Time
    Anticipated Study Start Date :
    Oct 1, 2023
    Anticipated Primary Completion Date :
    Oct 1, 2024
    Anticipated Study Completion Date :
    Oct 1, 2025

    Arms and Interventions

    Arm Intervention/Treatment
    Patients with parkinsonism

    Parkinsonism incl. tremor, parkinsons, atypical parkinsons

    Outcome Measures

    Primary Outcome Measures

    1. Correlation [over 7-10 yrs]

      Correlation between US findings and diagnosis

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years to 100 Years
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    No
    Inclusion Criteria:

    • Patients with parkinsonism or essential tremor who came into contact with our clinic before 2017

    • Satisfactory transcranial bone window

    • Previous TU (clinical indication)

    Exclusion Criteria:
    • No transcranial bone window

    Contacts and Locations

    Locations

    No locations specified.

    Sponsors and Collaborators

    • Region Skane

    Investigators

    None specified.

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    Region Skane
    ClinicalTrials.gov Identifier:
    NCT06032585
    Other Study ID Numbers:
    • Dnr 2022-06697-01
    First Posted:
    Sep 13, 2023
    Last Update Posted:
    Sep 13, 2023
    Last Verified:
    Sep 1, 2023
    Individual Participant Data (IPD) Sharing Statement:
    Undecided
    Plan to Share IPD:
    Undecided
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No
    Additional relevant MeSH terms:
    Parkinsonian Disorders

    Study Results

    No Results Posted as of Sep 13, 2023