Enhanced Recovery After Surgery for SPK Transplantation Recipients
Study Details
Study Description
Brief Summary
108 patients underwent elective SPK surgery were randomly divided into ERAS group (E) and routine care group (T). The ERAS group was consisted of evidenced-based systematic optimization approaches, while the control group received routine care.
Condition or Disease | Intervention/Treatment | Phase |
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N/A |
Detailed Description
Primary results: the postoperative length of stay (LoS) and hospitalization costs; second results: post-operative analgesia score (NRS) , the incidence of post-operative nausea and vomiting (PONV) , urinary catheter removal time by 7 days , post-operative gastric tube indwelling time, the incidence of ambulation within 6 days . the dosage of dobutamine using , the dosage of norepinephrine using, and the total amount of fluid and urine volume . MAP and lactate level . Peak systolic velocity (PSV) and (resistance index) RI of grafts were checked between two groups.
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
---|---|
Experimental: ERAS group ERAS group was consisted of evidenced-based systematic optimization approaches |
Procedure: Enhanced recovery for SPK recipients
Pre-operative, perioperative and post-operative were consisted of evidenced-based systematic optimization approaches.
|
No Intervention: Traditional group The control group received routine care |
Outcome Measures
Primary Outcome Measures
- Length of hospital stay (LoS) [Record all the period time from the day of admiting to hospital to the day of discharge from hospital(days).]
Record the time for SPK recipients of LoS (days)
- Hospital costs (US dollar) [Total costs(dollar) of the patients spended from the day of admiting to hospital to the day of discharge from hospital(days).]
The total cost of treatment for the patients.
Secondary Outcome Measures
- Perioperative complications [After the surgery acomplishment(see detail above):record the NRS within 40hours after the surgery, occurrence rate of the PPCs within 2 weeks after the surgery, ocurrence rate of the ambulation within 6 days after the surgery, etc.]
48 hours post-operative analgesia score (NRS), the incidence of post-operative nausea and vomiting (PONV) , urinary catheter removal time by 7 days , post-operative gastric tube indwelling time, the incidence of ambulation within 6 days
Eligibility Criteria
Criteria
Inclusion Criteria:
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Patients were aged 20-62 years
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Body mass index (BMI) of 18.5-32.9 kg/m2
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Voluntary participation for elective SPK surgery
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ERSD and DN patients waiting for SPK transplantation surgery.
Exclusion Criteria:
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History of allergy to narcotic drugs
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cardiopulmonary insufficiency
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congestive heart failure
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myasthenia gravis
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neurological disease
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mental illness
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severe liver dysfunction
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hyperkalaemia
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malignant hyperthermia
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unwilling to participate in the study for any reason, or had participated in another study within the 3 months
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
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1 | Second affiliated hospital of Guangzhou Medical University | Guangzhou | Guangdong | China | 510260 |
Sponsors and Collaborators
- Second Affiliated Hospital of Guangzhou Medical University
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- 2020-hs-67