Troponin Leaks in Emergency Department Patients Presenting With Supraventricular Tachycardia (SVT)

Sponsor

Spectrum Health - Lakeland (Other)

Overall Status

Completed

CT.gov ID

NCT02810561

Collaborator

(none)

Enrollment

Duration (Months)

Study Details

Study Description

Brief Summary

The goal of this study is twofold. First the investigators would like to determine the trajectory of troponin leaks; if it can be shown that the participants who have only minimal elevations of their repeat troponin universally decrease on the 3rd level then future patients may see significantly improved length of stay. Second, given conflicting results in the literature, the investigators would like to determine if elevated troponin levels correlate to later cardiovascular complications. These complications will be defined as Death, Myocardial Infarction, Cardiovascular intervention (such as coronary artery stenting or bypass). As the investigator is a single hospital system in this county it is uniquely positioned to be able to review this retrospectively.

Condition or Disease	Intervention/Treatment	Phase
Supraventricular Tachycardia	Other: No Intervention

Detailed Description

The investigators therefore propose retrospectively studying participants diagnosed with Supraventricular Tachycardia who had troponin(s) checked in the ED between January 1, 2012 and May 31, 2016 to allow a minimum of a year follow-up for our combined endpoint. The investigators will record the participants troponin value(s) in addition to the age, sex, race, heart rate, creatinine value. The investigators will compare the participants with positive troponins (and hopefully participants with strongly positive troponins) with those who are negative for troponin for presence of the combined end point via chart review.

Study Design

Study Type:

Observational

Actual Enrollment :

63 participants

Observational Model:

Cohort

Time Perspective:

Retrospective

Official Title:

Time Course and the Significance of Troponin Leaks in Emergency Department Patients Presenting With Supraventricular Tachycardia (SVT)

Study Start Date :

Jan 1, 2012

Actual Primary Completion Date :

Jul 1, 2016

Actual Study Completion Date :

Jul 1, 2016

Outcome Measures

Primary Outcome Measures

Troponin-I Level [6 hours after initial EKG]
Measured in ng/ml

Secondary Outcome Measures

Death/ Need for Cardiac Stent Placement or Coronary Bypass Artery Graft [6 months]

Eligibility Criteria

Criteria

Ages Eligible for Study:

N/A and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Yes

Inclusion Criteria:

Supraventricular Tachycardia with troponin elevation

Exclusion Criteria:

Other cardiac arrhythmias or conditions with increased troponin

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

Spectrum Health - Lakeland

Investigators

Principal Investigator: Matthew Hysell, MD, Lakeland Health Emergency Department

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

Responsible Party:

Spectrum Health - Lakeland

ClinicalTrials.gov Identifier:

NCT02810561

Other Study ID Numbers:

LH01

First Posted:

Jun 23, 2016

Last Update Posted:

Aug 17, 2022

Last Verified:

Aug 1, 2022

Individual Participant Data (IPD) Sharing Statement:

Undecided

Plan to Share IPD:

Undecided

Keywords provided by Spectrum Health - Lakeland

Troponin

Additional relevant MeSH terms:

Tachycardia

Tachycardia, Supraventricular

Emergencies

Study Results

No Results Posted as of Aug 17, 2022