Effect of Turner Syndrome on Number Sense

Sponsor

Stanford University (Other)

Overall Status

Withdrawn

CT.gov ID

NCT03459651

Collaborator

(none)

Enrollment

Location

Arm

Actual Duration (Days)

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

This study evaluates approximate number sense (ANS) in children, adolescents, and adult women with Turner syndrome compared to age-matched healthy peers. One primary aim of this project is to assess the effectiveness of an online ANS training tool in enhancing complex mathematics ability. Participants will undergo weekly training sessions in their own home. Half of the participants will complete 2 training sessions a week for 8 weeks, and the second half will complete 1 training session for 8 weeks.

Condition or Disease	Intervention/Treatment	Phase
Turner Syndrome	Behavioral: ANS training	N/A

Study Design

Study Type:

Interventional

Actual Enrollment :

0 participants

Allocation:

N/A

Intervention Model:

Single Group Assignment

Masking:

None (Open Label)

Primary Purpose:

Treatment

Official Title:

Investigation of the Role of Turner Syndrome on Approximate Number Sense

Actual Study Start Date :

Apr 1, 2022

Actual Primary Completion Date :

Apr 2, 2022

Actual Study Completion Date :

Apr 2, 2022

Arms and Interventions

Arm	Intervention/Treatment
Experimental: ANS training	Behavioral: ANS training In-home computer-based ANS training

Arm

Intervention/Treatment

Experimental: ANS training

Behavioral: ANS training

In-home computer-based ANS training

Outcome Measures

Primary Outcome Measures

Single and multiple-operand addition and subtraction accuracy [8 weeks]
Task accuracy calculated as the percentage of trials answered correctly.
Single and multiple-operand addition and subtraction response time [8 weeks]
Average amount of time, in seconds, required to answer each question on the task.

Eligibility Criteria

Criteria

Ages Eligible for Study:

6 Years to 40 Years

Sexes Eligible for Study:

Female

Accepts Healthy Volunteers:

Yes

Inclusion Criteria:

Children, adolescents, and adult women with Turner syndrome.
Healthy controls.
Normal or corrected to normal vision.

Exclusion Criteria:

Major psychiatric or developmental disorder (e.g., bipolar disorder, major depression, psychotic disorders, intellectual disability, autism spectrum disorder).
Chemical dependency
Currently taking the following medications: antidepressant, antipsychotic, and anti-seizures drugs.

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Center for Interdisciplinary Brain Sciences Research	Stanford	California	United States	94305

Sponsors and Collaborators

Stanford University

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

Responsible Party:

Joseph Michael Baker, Instructor, Stanford University

ClinicalTrials.gov Identifier:

NCT03459651

Other Study ID Numbers:

092883

First Posted:

Mar 9, 2018

Last Update Posted:

May 9, 2022

Last Verified:

May 1, 2022

Individual Participant Data (IPD) Sharing Statement:

Undecided

Plan to Share IPD:

Undecided

Studies a U.S. FDA-regulated Drug Product:

Studies a U.S. FDA-regulated Device Product:

Keywords provided by Joseph Michael Baker, Instructor, Stanford University

numeracy

number sense

Additional relevant MeSH terms:

Turner Syndrome

Gonadal Dysgenesis

Syndrome

Study Results

No Results Posted as of May 9, 2022