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Standardized Management of Complex Twins

Sponsor
Caixia Liu (Other)
Overall Status
Not yet recruiting
CT.gov ID
NCT04921150
Collaborator
Shengjing Hospital (Other)
100
Enrollment
39
Anticipated Duration (Months)

Study Details

Study Description

Brief Summary

At present, the incidence of monochorionic twins in all pregnancies is around 3-5‰ worldwide.In 2019, the twin Committee of China Maternal and Child Health Association conducted statistics from 48 medical units all over the country, showing that there were 4,876 cases of monochorionic twins, accounting for 10.2‰ of all pregnancies.In addition to increased incidence of preterm delivery, miscarriage, and maternal complication, the unique placental vascular structure of monochorionic twins is associated with complex fetal complication such as twin-twin transfusion syndrome, selective intraurine growth restriction, twin anaemia-erythrocytosis sequence, twin reversed arterial perfusion sequence, one of twin with dysplasia, twins with single amniotic sac and conjunctions are common. At present, there is no unified standard for the diagnosis and treatment of these complicated twins, and various treatment methods have a great impact on the pregnancy outcome and fetal prognosis.Therefore, the standardized management of complex twins benefits diagnosis and treatment of complex twins and improves fetal prognosis.

Condition or Disease Intervention/Treatment Phase
  • Other: standardization management
 N/A

Study Design

Study Type:
Interventional
Anticipated Enrollment :
100 participants
Allocation:
Non-Randomized
Intervention Model:
Sequential Assignment
Masking:
None (Open Label)
Primary Purpose:
Treatment
Official Title:
Standardized Management of Complex Twins
Anticipated Study Start Date :
Jun 1, 2021
Anticipated Primary Completion Date :
Sep 1, 2024
Anticipated Study Completion Date :
Sep 1, 2024

Outcome Measures

Primary Outcome Measures

  1. Standardized management system of twin pregnancy clinic [1 year]

    S/D score and Apgar score of complex twin pregnancy assessed by clinical doctors

Eligibility Criteria

Criteria

Ages Eligible for Study:
N/A and Older
Sexes Eligible for Study:
Female
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:

complex twin disease 18-45 years

Exclusion Criteria:

single pregnancy normal twin pregnancy

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

  • Caixia Liu
  • Shengjing Hospital

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Caixia Liu, Clinical Professor, Shengjing Hospital
ClinicalTrials.gov Identifier:
NCT04921150
Other Study ID Numbers:
  • SMOCT
First Posted:
Jun 10, 2021
Last Update Posted:
Jun 10, 2021
Last Verified:
Jun 1, 2021
Individual Participant Data (IPD) Sharing Statement:
No
Plan to Share IPD:
No
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No

Study Results

No Results Posted as of Jun 10, 2021