Home-HIT and Type 1 Diabetes
Study Details
Study Description
Brief Summary
This study aimed to use a multi-disciplinary approach to evaluate a 6-week home-based high-intensity interval training (Home-HIT) intervention in people with type 1 diabetes.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
N/A |
Detailed Description
This study aimed to use a multi-disciplinary approach to evaluate a home-based high-intensity interval training (Home-HIT) intervention in people with type 1 diabetes.
Eleven individuals with type 1 diabetes (4 men/7 women; age 30±3 years; BMI 27.1±1.2 kg·m-2; V ̇O2peak 32.4±2.1 ml∙kg∙min-1; duration of type 1 diabetes 10±2 years) completed six weeks of Home-HIT. The effect of Home-HIT on V ̇O2peak, blood pressure, insulin dose and glycaemic profile was assessed pre and post-training. Adherence and ability to meet target heart rate (HR) thresholds (compliance) were monitored using a HR monitor and mobile phone application. Change in glycaemia was measured pre, post and 1h post exercise sessions throughout the six-week period. A qualitative online survey was completed post-training.
This is the first study to combine physiological outcomes with a qualitative evaluation of a training intervention in people with type 1 diabetes. Home-HIT resulted in high adherence alongside increased V ̇O2peak and decreased insulin dose. Because Home-HIT is time-efficient and removes barriers to exercise including fear of hypoglycaemia, it may represent an effective strategy to increase exercise participation in people with type 1 diabetes.
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Experimental: Training 6 weeks of home-based high intensity interval training |
Behavioral: Home-HIT
Participants completed 6 weeks of home-based high-intensity interval training 3 times per week
|
Outcome Measures
Primary Outcome Measures
- change in maximal aerobic capacity [change in baseline maximal aerobic capacity at 6 weeks]
Maximal aerobic capacity was measured pre and post 6 week training intervention using a MOXUS gas analyser on a stationary cycle ergometer
- adherence over the course of the training programme [adherence to the training programme over the course of the 6 week intervention]
session completion rate (adherence) was assessed
- Compliance over the course of the training programme [compliance to the training programme over the course of the 6 week intervention]
ability to meet target heart rates (compliance) was assessed
Secondary Outcome Measures
- change in insulin sensitivity [change in baseline insulin sensitivity at 6 weeks]
insulin dose was recorded pre and post training by participants
- change in glycaemic control [change in baseline glycaemic control at 6 weeks]
participants recorded their blood glucose concentrations in the first and final weeks of the intervention
Eligibility Criteria
Criteria
Inclusion Criteria:
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duration of type 1 diabetes >6 months,
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no significant history of hyper- or hypoglycaemia
Exclusion Criteria:
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duration of type 1 diabetes <6 months,
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significant history of hyper- or hypoglycaemia,
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pregnancy or planning pregnancy,
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uncontrolled hypertension (>180/100 mmHg),
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angina
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autonomic neuropathy,
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taking any medication that affects heart rate (HR)
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major surgery planned within 6 weeks of the study
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severe nonproliferative
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unstable proliferative retinopathy
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Liverpool John Moores University | Liverpool | Merseyside | United Kingdom | L3 3AF |
Sponsors and Collaborators
- Liverpool John Moores University
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- Home-HIT_T1D