Ultrasonographic Predictors of Hypotension After Induction

• Sponsor: Antalya Training and Research Hospital (Other)
• Overall Status: Recruiting
• CT.gov ID: NCT05239234
• Collaborator: (none)
• Enrollment: 100
• Location: 1
• Anticipated Duration (Months): 3
• Patients Per Site Per Month: 33.4

Study Details

Study Description

Brief Summary

The purpose of the study is to evaluate the predictive value of the inferior vena cava collapsibility index and caval aorta index for detecting hypotension after induction of general anesthesia.

Condition or Disease	Intervention/Treatment	Phase
General Anesthesia; Hypotension on Induction	Other: Inferior vena cava-Aorta diameter index

Detailed Description

Since cardiovascular depressant and vasodilatory effects of anesthetic agents, patients may be at risk of hypotension after induction of general anesthesia. Previous studies reported that, for evaluating volume status, some ultrasonographic measurements such as inferior vena cava collapsibility index (IVCCI) could be used. Also some studies stated that measurement of aorta diameter index (IVC : Ao index) is reliable to predict hypotension after induction of spinal anesthesia. At the study, the investigators aimed to investigate the predictive values of the inferior vena cava collapsibility index and caval aorta index under ultrasound guidance in predicting post-induction hypotension in patients under general anesthesia.

Study Design

• Study Type: Observational
• Anticipated Enrollment: 100 participants
• Observational Model: Cohort
• Time Perspective: Prospective
• Official Title: Pre-operative Ultrasonographic Evaluation of Inferior Vena Cava Collapsibility Index and Caval Aorta Index to Predict Hypotension After Induction of General Anesthesia
• Actual Study Start Date: Mar 2, 2022
• Anticipated Primary Completion Date: May 1, 2022
• Anticipated Study Completion Date: Jun 1, 2022

Outcome Measures

Primary Outcome Measures

1. Diagnostic value of IVCCI to detect post-induction hypotension assessed by Receiver operating characteristic (ROC) curve analysis. [20 minutes]

   Measurement of inferior vena cava collapsibility index.

2. Diagnostic value of IVC : Ao index to detect post-induction hypotension assessed by ROC curve analysis. [20 minutes]

   Measurement of inferior vena cava-Aorta diameter index.

Eligibility Criteria

Criteria

• Ages Eligible for Study: 18 Years to 75 Years
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:

• patients more than 18 years of age

• American Society of Anesthesiologists' (ASA) physical status 1 or 2

Exclusion Criteria:

• BMI more than 30 kg/m²

• Use of angiotensin converting enzyme inhibitors

• pregnancy,

• emergency operations

• baseline arterial systolic blood pressure less than 90 mmHg

• mean arterial blood pressure less than 70 mmHg

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Antalya Training and Researching Hospital	Antalya		Turkey

Sponsors and Collaborators

• Antalya Training and Research Hospital

Investigators

• Principal Investigator: Enes Eskin, M.D., Antalya Training and Research Hospital

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: Antalya Training and Research Hospital
• ClinicalTrials.gov Identifier: NCT05239234
• Other Study ID Numbers: AntalyaTRH55
• First Posted: Feb 14, 2022
• Last Update Posted: Mar 16, 2022
• Last Verified: Jan 1, 2022

• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No
• Additional relevant MeSH terms: Hypotension

Study Results

No Results Posted as of Mar 16, 2022