An Evaluation of a Dynamic Web-Based Visualization of Community Immunity

Sponsor

Laval University (Other)

Overall Status

Not yet recruiting

CT.gov ID

NCT04787913

Collaborator

(none)

5,440

Enrollment

Arms

Anticipated Duration (Months)

Study Details

Study Description

Brief Summary

This study is a PhD project conducted by Ms. Hina Hakim, supervised by Dr. Holly O. Witteman, PhD, and co-supervised Dr. Daniel Reinharz, professors and researchers at the Faculty of Medicine at Laval University. The purpose of this study is to evaluate the effects of visualization conveying the concept of community immunity or herd immunity on risk perception (towards individual, family, community and vulnerable people in communities) (primary outcome) and on emotions, attitudes, knowledge, and behavioural intentions (secondary outcomes).

Condition or Disease	Intervention/Treatment	Phase
Understanding of Community Immunity as a Concept	Behavioral: herdimm Behavioral: guardianmeasles Behavioral: theotheredmundmeasles Behavioral: sbsnewsgeneric Behavioral: publichealthagencycanadaflu Behavioral: robertkochgeneric	N/A

Detailed Description

Visualization is a powerful communication mechanism that uses pre-attentive processing to communicate large amounts of information rapidly in understandable and compelling ways (Healey and Enns 2012). A systematic review demonstrates that there are some interventions available for conveying the concept of community immunity, and very few evaluate interventions for their effects on vaccine intentions and uptake as well as their precursors, such as knowledge, attitudes, knowledge and none on emotions (Hakim et al. 2018).

The purpose of this study is to evaluate the effects of visualization conveying the concept of community immunity on risk perception (to individual, family, community and vulnerable people in communities) (primary outcome) and on emotions, attitudes, knowledge, and behavioural intentions (secondary outcomes).

Study Design

Study Type:

Interventional

Anticipated Enrollment :

5440 participants

Allocation:

Randomized

Intervention Model:

Factorial Assignment

Intervention Model Description:

This study will be a multi-armed factorial randomized controlled trial. Each participant will be randomly allocated to focus on one of four possible vaccine-preventable diseases: measles, pertussis, flu (influenza), or a generic vaccine-preventable disease (hereby referred to as "generic"). All aspects of the study (visualization, questionnaire) will be focused on that one disease for that participant. The primary and secondary outcomes of the study which are risk perception, emotion, knowledge, trust in information provided, attitudes and a validated scale about vaccination (Betsch et al. 2018) will be assessed in an online questionnaire. Because three online visualizations are available only in English whereas our study will be conducted in both English and French, we will use slightly different randomization patterns for English- and French-speaking participants.This study will be a multi-armed factorial randomized controlled trial. Each participant will be randomly allocated to focus on one of four possible vaccine-preventable diseases: measles, pertussis, flu (influenza), or a generic vaccine-preventable disease (hereby referred to as "generic"). All aspects of the study (visualization, questionnaire) will be focused on that one disease for that participant. The primary and secondary outcomes of the study which are risk perception, emotion, knowledge, trust in information provided, attitudes and a validated scale about vaccination (Betsch et al. 2018) will be assessed in an online questionnaire. Because three online visualizations are available only in English whereas our study will be conducted in both English and French, we will use slightly different randomization patterns for English- and French-speaking participants.

Masking:

Single (Investigator)

Masking Description:

This will be a single-blinded study because we cannot mask participants to the fact that they have been randomized to a visualization e.g., about measles. However, participants will not necessarily know the purpose of the study arm to which they are assigned,and investigators will be blinded to study arm during data analysis (investigators are not aware of whether the next eligible participant will be receiving treatment or control intervention.)

Primary Purpose:

Health Services Research

Official Title:

An Evaluation of a Dynamic Web-Based Visualization of Community Immunity

Anticipated Study Start Date :

Mar 1, 2021

Anticipated Primary Completion Date :

May 1, 2021

Anticipated Study Completion Date :

Dec 1, 2021

Arms and Interventions

Arm	Intervention/Treatment
No Intervention: controlgeneric No intervention provided. Participant answers outcome questions about an unnamed vaccine-preventable disease. English and French.
No Intervention: controlmeasles No intervention provided. Participant answers outcome questions about measles. English and French.
No Intervention: controlpertussis No intervention provided. Participant answers outcome questions about pertussis. English and French.
No Intervention: controlflu No intervention provided. Participant answers outcome questions about flu. English and French.
Experimental: herdimmgeneric Web-based application (main intervention) provided. Participant answers outcome questions about an unnamed vaccine-preventable disease. English and French.	Behavioral: herdimm In this visualization participants can build their own avatar representing themselves and 8 other avatars representing people around them, like their family or coworkers. Our visualization then uses these avatars in a brief narrated video explaining how herd immunity works.
Experimental: herdimmmeasles Web-based application (main intervention) provided. Participant answers outcome questions about measles. English and French.	Behavioral: herdimm In this visualization participants can build their own avatar representing themselves and 8 other avatars representing people around them, like their family or coworkers. Our visualization then uses these avatars in a brief narrated video explaining how herd immunity works.
Experimental: herdimmpertussis Web-based application (main intervention) provided. Participant answers outcome questions about pertussis. English and French.	Behavioral: herdimm In this visualization participants can build their own avatar representing themselves and 8 other avatars representing people around them, like their family or coworkers. Our visualization then uses these avatars in a brief narrated video explaining how herd immunity works.
Experimental: herdimmflu Web-based application (main intervention) provided. Participant answers outcome questions about flu. English and French.	Behavioral: herdimm In this visualization participants can build their own avatar representing themselves and 8 other avatars representing people around them, like their family or coworkers. Our visualization then uses these avatars in a brief narrated video explaining how herd immunity works.
Active Comparator: robertkochgeneric Web-based application (comparator) provided. Participant answers outcome questions about an unnamed vaccine-preventable disease. English only.	Behavioral: robertkochgeneric A web-based application showing how herd immunity works in general: http://rocs.hu-berlin.de/D3/herd/
Active Comparator: sbsnewsgeneric Video (comparator) provided. Participant answers outcome questions about an unnamed vaccine-preventable disease. English only.	Behavioral: sbsnewsgeneric A video showing how herd immunity works in general: https://www.sbs.com.au/news/two-sydney-babies-too-young-to-be-vaccinated-infected-with-measles
Active Comparator: guardianmeasles Video (comparator) provided. Participant answers outcome questions about measles. English only.	Behavioral: guardianmeasles A screen capture of an interactive visualization: https://www.theguardian.com/society/ng-interactive/2015/feb/05/-sp-watch-how-measles-outbreak-spreads-when-kids-get-vaccinated
Active Comparator: theotheredmundmeasles Video (comparator) provided. Participant answers outcome questions about measles. English only.	Behavioral: theotheredmundmeasles A gif showing measles spreading through populations with differing levels of vaccine coverage: https://imgur.com/gallery/8M7q8#J7LANQ4
Active Comparator: publichealthagencycanadaflu Video (comparator) provided. Participant answers outcome questions about flu. English and French.	Behavioral: publichealthagencycanadaflu A video showing how herd immunity works in the context of influenza: https://www.canada.ca/fr/sante-publique/services/video/la-grippe-n-en-passez-pas-les-maux.html

Outcome Measures

Primary Outcome Measures

Risk perception [immediately after intervention or control]
6 ad hoc questions assessing risk perception

Secondary Outcome Measures

emotions, attitudes, knowledge, and behavioural intentions [immediately after intervention or control]
ad hoc questions and 5C scale (Betsch et al.)

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Yes

Inclusion Criteria:

Members of the general population in Canada
At least 18 years old
Able to provide free and informed consent
Able to read and understand French or English
Able to use a computer

Exclusion Criteria:

No internet access

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

Laval University

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

Responsible Party:

Laval University

ClinicalTrials.gov Identifier:

NCT04787913

Other Study ID Numbers:

herdimm

First Posted:

Mar 9, 2021

Last Update Posted:

Mar 9, 2021

Last Verified:

Mar 1, 2021

Individual Participant Data (IPD) Sharing Statement:

Yes

Plan to Share IPD:

Yes

Studies a U.S. FDA-regulated Drug Product:

Studies a U.S. FDA-regulated Device Product:

Keywords provided by Laval University

herd immunity

community immunity

web-based application

visualization

Study Results

No Results Posted as of Mar 9, 2021