LTDEP: To Map Human Lower Thoracic Dermatomes by Epidural Block

Sponsor
Tongji Hospital (Other)
Overall Status
Completed
CT.gov ID
NCT03022136
Collaborator
(none)
50
1
1
4.9
10.1

Study Details

Study Description

Brief Summary

Significant differences exist among various dermatome maps. In addition, there were no anatomical landmarks to evaluate the dermatome at the back. The investigators aim to map the sensory innervations of lower thoracic nerves and find the dorsal landmarks to evaluate sensory innervations by epidural block. Patients undergoing urological surgery will receive epidural block. Fifty patients with superior border of complete sensory loss to ice from T9 to T12 (anterior median line) will be included in this study. The sensory loss to ice will be evaluated at midclavicular line, anterior axillary line, posterior axillary line, scapular line and posterior median line. The level of vertebrae will be identified and marked by ultrasound. The superior border of complete sensory loss to ice from anterior median line to posterior median line will be recorded for every patient. The dermatome map of T9 to T12 will be drawn. The landmarks of sensory innervations at posterior median line will be established using vertebrae.

Condition or Disease Intervention/Treatment Phase
  • Other: cold sensation method
N/A

Detailed Description

Background: The tract for percutaneous nephrolithotomy is typically established in the 11th intercostal space or in the subcostal area. According to Keegan and Garrett's dermatome map, the somatic pain could be controlled if the 11th and 12th the spinal nerve been blocked. However, the investigators found that if the 11th and the 12th spinal nerve had been blocked by evaluating the landmarks of ventral landmarks (xiphoid process , umbilicus and pubic symphysis), the somatic pain of percutaneous nephrolithotomy could not be controlled. In order to find the reason, the investigators compared the four main dermatome maps created by Henry Head, Foerster, Keegan and Lee. There are significant differences of dermatome among these maps. In addition, there were no landmarks to evaluate the dermatome at the back.

Objectives: To map the sensory innervations of lower thoracic nerves and find the dorsal landmarks to evaluate sensory innervations by epidural block.

Methods: Adult patients undergoing elective percutaneous nephrolithotomy, ureteroscopic lithotripsy, transuretheral resection of prostate and transuretheral resection of bladder tumor will receive epidural block with 0.5% ropivacaine. Complete Sensory loss to ice will be evaluated at anterior median line as soon as the surgery was completed. The superior border of complete sensory loss to ice will be identified by ventral landmaks (xiphoid process , umbilicus and pubic symphysis). Fifty patients with superior border of complete sensory loss to ice from T9 to T12 will be included in this study. The sensory loss to ice will be evaluated at anterior median line, midclavicular line, anterior axillary line, posterior axillary line, scapular line and posterior median line. The level of vertebrae will be identified and marked by ultrasound. The superior border of complete sensory loss to ice form anterior median line to posterior median line will be drawn and recorded for every patient. The dermatome map from T9 to T12 will be drawn. The landmarks of sensory innervations at posterior median line will be established using vertebrae..

Study Design

Study Type:
Interventional
Actual Enrollment :
50 participants
Allocation:
N/A
Intervention Model:
Single Group Assignment
Masking:
None (Open Label)
Primary Purpose:
Other
Official Title:
Observation Study of Thoracic Dermatomes
Actual Study Start Date :
Feb 1, 2017
Actual Primary Completion Date :
Jul 1, 2017
Actual Study Completion Date :
Jul 1, 2017

Arms and Interventions

Arm Intervention/Treatment
Experimental: Epidural Block

Epidural block for patients undergoing urological surgery

Other: cold sensation method
Complete sensory loss to ice will be evaluated form anterior median line to posterior median line at the end of surgery.

Outcome Measures

Primary Outcome Measures

  1. Superior border of sensory block was assessed by cold sensation method [at the end of surgery]

    The sensory loss to ice will be evaluated at anterior median line, midclavicular line, anterior axillary line, posterior axillary line, scapular line and posterior median line. The level of vertebrae will be identified and marked by ultrasound. The upper border of complete sensory loss to ice form anterior median line to posterior median line will be drawn and recorded for every patient.

Eligibility Criteria

Criteria

Ages Eligible for Study:
18 Years to 60 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
  • Patients scheduled for percutaneous nephtolithotomy, ureteroscopy lithotripsy, transurethral resection of bladder tumor or transurethral resection of the prostate

  • American Society of Anesthesiologists physical statusⅠ-Ⅲ

  • Informed consent

Exclusion Criteria:
  • Coagulopathy, on anticoagulants

  • History of surgery on spine

  • Spine deformity

  • A known allergy to the drugs being used

  • Tumer or infection at the site of puncture

  • refusal to participate in the study

Contacts and Locations

Locations

Site City State Country Postal Code
1 Tongji Hospital Wuhan Hubei China 430030

Sponsors and Collaborators

  • Tongji Hospital

Investigators

  • Principal Investigator: Yong Liu, MD, Department of Anesthesiology,Tongji Hospital,Wuhan

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Liu Yong, Principal Investigator, Tongji Hospital
ClinicalTrials.gov Identifier:
NCT03022136
Other Study ID Numbers:
  • Der-201701
First Posted:
Jan 16, 2017
Last Update Posted:
Jul 17, 2018
Last Verified:
Jul 1, 2018
Individual Participant Data (IPD) Sharing Statement:
Yes
Plan to Share IPD:
Yes
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Keywords provided by Liu Yong, Principal Investigator, Tongji Hospital
Additional relevant MeSH terms:

Study Results

No Results Posted as of Jul 17, 2018