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SpeckleShake: Use of Laser Speckle to Study Post Occlusive Reactive Hyperhemia in Healthy Subjects

Sponsor
University Hospital, Angers (Other)
Overall Status
Completed
CT.gov ID
NCT01169974
Collaborator
(none)
41
Enrollment
1
Location
22.1
Actual Duration (Months)
1.9
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The investigators aim to test the hypothesis that Laser speckle contrast imaging allows for the measurement of cutaneous blood flow following various durations of tourniquet ischemia.

Condition or Disease Intervention/Treatment Phase
  • Other: tourniquet ischemia

Detailed Description

Ischemia and post occlusive reactive hyperemia in the skin is tested in healthy normal subjects for tourniquet ischemias of 1, 2 & 3 minutes at rest.

Study Design

Study Type:
Observational
Actual Enrollment :
41 participants
Observational Model:
Cohort
Time Perspective:
Prospective
Official Title:
Evaluation Chez Des Sujets Volontaires Sains de l'ischémie-reperfusion cutanée
Actual Study Start Date :
Feb 1, 2011
Actual Primary Completion Date :
Sep 1, 2012
Actual Study Completion Date :
Dec 4, 2012

Arms and Interventions

Arm Intervention/Treatment
healthy volunteers

Other: tourniquet ischemia
Recording of cutaneous blood flow on the forearm at rest before and following tourniquet ischemias of 1 , 2 & 3 minutes
Other Names:
  • Laser doppler flowmetry
  • Transcutaneous oxygen pressure
  • Near infra-red spectrometry
  • Plethysmography

    		•

    Outcome Measures

    Primary Outcome Measures

    1. Laser speckle [with 2 minutes of ischemia]

      Peak value of laser speckle signal

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years and Older
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    Yes
    Inclusion Criteria:

    • Healthy volunteers

    • Affiliation to the French health system

    Exclusion Criteria:
    • Any disease or chronic treatment

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 University hospital Angers France

    Sponsors and Collaborators

    • University Hospital, Angers

    Investigators

    • Principal Investigator: Guillaume Mahe, University Hospital in Angers

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    University Hospital, Angers
    ClinicalTrials.gov Identifier:
    NCT01169974
    Other Study ID Numbers:
    • CHU P 2010-18
    First Posted:
    Jul 26, 2010
    Last Update Posted:
    Nov 1, 2017
    Last Verified:
    Oct 1, 2017
    Keywords provided by University Hospital, Angers
    Microcirculation
    laser flowmetry
    Skin
    Physiology

    Study Results

    No Results Posted as of Nov 1, 2017