CDS: In Utero Capacity Formation and Socio-economic Outcomes

Sponsor

Harvard University (Other)

Overall Status

Completed

CT.gov ID

NCT01412580

Collaborator

(none)

4,000

Enrollment

Location

137

Duration (Months)

29.2

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Because of the high returns of schooling in developing countries, policymakers pay a lot of attention to increasing school access. But if the mother is deficient in key micronutrients, brain development can biologically constrain children's demand for education. To execute this strategy, the investigators collect cohort observational data on a previous randomized controlled trial with micronutrient supplements offered to HIV-negative pregnant women in Dar es Salaam, Tanzania, between 2001 to 2003.

Condition or Disease	Intervention/Treatment	Phase
Folic Acid Deficiency	Other: observational follow-up

Detailed Description

This is a cohort study which collected follow-up observational data on households which were offered micronutrient supplements. The followup study outcomes include various socio-economic household characteristics and parental post-natal behaviors.

Study Design

Study Type:

Observational

Actual Enrollment :

4000 participants

Observational Model:

Family-Based

Time Perspective:

Prospective

Official Title:

The Contribution of Health in Utero to Capacity Formation, Education and Economic Outcomes: Experimental Evidence From Tanzania

Study Start Date :

Apr 1, 2002

Actual Primary Completion Date :

Sep 1, 2012

Actual Study Completion Date :

Sep 1, 2013

Arms and Interventions

Arm	Intervention/Treatment
observational followup This was an observational follow-up to a larger study in which treatment group was given 20 mg of vitamin B1, 20 mg of vitamin B2, 25 mg of vitamin B6, 100 mg of niacin, 50 μg of vitamin B12, 500 mg of vitamin C, 30 mg of vitamin E, and 0.8 mg of folic acid	Other: observational follow-up observational follow-up

Arm

Intervention/Treatment

observational followup

This was an observational follow-up to a larger study in which treatment group was given 20 mg of vitamin B1, 20 mg of vitamin B2, 25 mg of vitamin B6, 100 mg of niacin, 50 μg of vitamin B12, 500 mg of vitamin C, 30 mg of vitamin E, and 0.8 mg of folic acid

Other: observational follow-up

observational follow-up

Outcome Measures

Primary Outcome Measures

Children's Cognitive Development [During 2011-2012 (1 year)]
Children's Health [During 2011-2012 (1 year)]
BMI, Disease Incidence, Self-reported health
Parental Postnatal Investment Behavior [During 2011-2012 (1 year)]
Outcomes on parental care: care, cognitive stimulation, within-household time and money allocation
Educational Status [During 2011-2012 (1 year)]
School attendance, Student performance (at school), Test Performance

Secondary Outcome Measures

Parental Labor Force Participation [During 2011-2012 (1 year)]
Parent's labor force outcomes: labor status, wages, type of job

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years to 49 Years

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Yes

These were individuals from the larger study and this study is an observational follow-up.

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	MUHAS	Dar es Salaam		Tanzania

Sponsors and Collaborators

Harvard University

Investigators

Study Director: Plamen Nikolov, Harvard University

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

Responsible Party:

Plamen Nikolov, Study Director, Harvard University

ClinicalTrials.gov Identifier:

NCT01412580

Other Study ID Numbers:

F19899-101

First Posted:

Aug 9, 2011

Last Update Posted:

Aug 7, 2019

Last Verified:

Aug 1, 2019

Individual Participant Data (IPD) Sharing Statement:

Plan to Share IPD:

Additional relevant MeSH terms:

Folic Acid Deficiency

Study Results

No Results Posted as of Aug 7, 2019