Retrospective Register for Uveal Melanoma

Sponsor

Medical University of Vienna (Other)

Overall Status

Recruiting

CT.gov ID

NCT05733728

Collaborator

(none)

1,400

Enrollment

Location

95.2

Anticipated Duration (Months)

14.7

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Background: Uveal melanoma (UM) is a common primary ocular malignancy associated with limited overall survival in the advanced stage of the disease. Fundamental breakthrough regarding the management of the disease and the overall-survival have not yet been achieved. Studies with large cohorts are difficult to perform due to limited patient numbers, therefore retrospective analyses are of great potential to gain further knowledge in a disease with high clinical needs.

Aim: The proposed project is a register for patients with UM treated at the Department of Ophthalmology and Optometry at the Medical University of Vienna between 01.01.1997 and 31.12.2021.

Patients and Methods: Patients treated for UM at the Department of Ophthalmology and Optometry at the Medical University of Vienna between 01.01.1997 and 31.12.2021 will be included in the register. Information on the baseline characteristics, survival times and course of the disease will be gathered via retrospective chart review and saved in a password-secured database.

Condition or Disease	Intervention/Treatment	Phase
Uveal Melanoma	Other: any therapy suitable

Study Design

Study Type:

Observational [Patient Registry]

Anticipated Enrollment :

1400 participants

Observational Model:

Cohort

Time Perspective:

Other

Official Title:

Retrospective Register for Uveal Melanoma

Actual Study Start Date :

Jan 23, 2023

Anticipated Primary Completion Date :

Dec 31, 2030

Anticipated Study Completion Date :

Dec 31, 2030

Arms and Interventions

Arm	Intervention/Treatment
Uveal Melanoma	Other: any therapy suitable any therapy suitable

Arm

Intervention/Treatment

Uveal Melanoma

Other: any therapy suitable

any therapy suitable

Outcome Measures

Primary Outcome Measures

Conduction of a Register providing the basis for [1997-2021]
Retrospective studies analyzing the obtained data and easy identification of patients for prospective studies (e.g. long-term survival analysis)

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years to 99 Years

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria

Patients 18 - 99 years
Diagnosis of uveal melanoma Exclusion Criteria
Patients younger than 18 years of age
Inadequate or missing information on the clinical course in patient charts

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Medical University of Vienna	Vienna		Austria	1090

Sponsors and Collaborators

Medical University of Vienna

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

Responsible Party:

Reinhard Told, MD, Medical University of Vienna

ClinicalTrials.gov Identifier:

NCT05733728

Other Study ID Numbers:

1942/2022

First Posted:

Feb 17, 2023

Last Update Posted:

Feb 17, 2023

Last Verified:

Feb 1, 2023

Individual Participant Data (IPD) Sharing Statement:

Plan to Share IPD:

Studies a U.S. FDA-regulated Drug Product:

Studies a U.S. FDA-regulated Device Product:

Additional relevant MeSH terms:

Melanoma

Uveal Neoplasms

Study Results

No Results Posted as of Feb 17, 2023