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The V-Tachogram:Decreasing Ventricular Arrythmias When Injecting Contrast in the Left Ventricle

Sponsor
Trillium Health Centre (Other)
Overall Status
Unknown status
CT.gov ID
NCT00288756
Collaborator
(none)
156
Enrollment
1
Location
1
Duration (Months)
153.2
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The purpose of this study is to determine if increasing the linear rise rate of injection of x-ray contrast in the heart during left ventriculograms(part of a cardiac Catheterization procedure) will decrease the incidence of arrythmias and improve image quality?

Condition or Disease Intervention/Treatment Phase
  • Procedure: lv injection of contrast

Detailed Description

The LV angiogram is performed frequently as part of the cardiac catheterization procedure. It is done by injecting a bolus of x-ray contrast into the ventricle through a pigtail catheter over a short period of time and observing the heart as it is pumped out. This provides information on regional wall motion abnormalities, ejection fraction, and mitral regurgitation. A common occurrence when performing a LV angio is frequent PVC's or V-tach during the injection, it has been suggested that ectopic's occurs about 54% of the time and that interpretability was limited 30% of the time(3) This is rarely serious and subsides at the end of the injection but the irregularity of the contractions does affect the diagnostic quality of the exam.

In an attempt to decrease the incidence of ventricular ectopic's during the LV angiogram Contrast injections with a greater linear rise increasing the injection duration to at least ½ the flow rate, greater than previous settings should decrease the tension and the contrast jets coming out of the catheter, decreasing the fling of the catheter at the initiation of the injection. Whether this affects the quality of the angiogram with a pig tail vs. a straight catheter will also need to be considered?

Study Design

Study Type:
Observational
Observational Model:
Defined Population
Time Perspective:
Other
Study Start Date :
Jul 1, 2006
Study Completion Date :
Aug 1, 2006

Outcome Measures

Primary Outcome Measures

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    0 Years and Older
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    Yes
    Inclusion Criteria:
    • Only ventriculograms that the operator deems necessary for the booked procedure will be considered. Only operators agreeing to the for mentioned settings will participate in the study. Patients will be randomized consecutively and should conclude in 3 to 4 weeks.
    Exclusion Criteria:
    • Patients with aortic valve disease, a-fib, and frequent benign ectopic beats and patients unable to follow instructions to stop breathing will be excluded.

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Trillium Health Centre Mississauga Ontario Canada L5B 1B8

    Sponsors and Collaborators

    • Trillium Health Centre

    Investigators

    • Principal Investigator: Peter Vandermyden, RN, staff RN Trillium Health Centre

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    , ,
    ClinicalTrials.gov Identifier:
    NCT00288756
    Other Study ID Numbers:
    • 01
    First Posted:
    Feb 8, 2006
    Last Update Posted:
    Sep 13, 2006
    Last Verified:
    Sep 1, 2006
    Keywords provided by , ,
    arrythmias
    Additional relevant MeSH terms:
    Arrhythmias, Cardiac

    Study Results

    No Results Posted as of Sep 13, 2006