VA Genetic Tissue Banking

Sponsor

US Department of Veterans Affairs (U.S. Fed)

Overall Status

Completed

CT.gov ID

NCT00032578

Collaborator

(none)

1,000

Enrollment

Locations

125

Patients Per Site

Study Details

Study Description

Brief Summary

This project is a program-wide genetic tissue databank for the Department of Veterans Affairs Cooperative Studies Program (CSP). The genetic tissue bank has four components: a central repository for DNA and other genetic tissue specimens; a Scientific Advisory Committee of individuals with expertise in the genetics and epidemiology of diseases with special importance to the VA (including cardiovascular, neurologic, respiratory, psychological and other disorders); an Ethics Oversight Committee of individuals with expertise in bioethics and the law, as they apply to the collection and use of genetic tissue, and a Coordinating Center that administers the tissue bank, coordinates the scientific and ethics oversight committees, maintains central access to clinical study data linked to the tissue bank, and provides statistical analysis.

Condition or Disease	Intervention/Treatment	Phase
Tissue Banking

Detailed Description

Intervention: No intervention.

Primary Hypothesis: It is feasible and cost-effective to create a CSP-wide facility for banking genetic tissue in CSP studies.

Study Abstract: This is a program-wide genetic tissue databank for the Department of Veterans Affairs Cooperative Studies Program (CSP). The study has five components: a central repository for DNA and other genetic tissue specimens; a Scientific Advisory Committee of individuals with expertise in the genetics and epidemiology of diseases with special importance to the VA (including cardiovascular, neurologic, respiratory, psychological and other disorders); an Ethical Oversight Committee of individuals with expertise in bioethics and the law, as they apply to the collection and use of genetic tissue, A Veteran's Advisory Group, and a Coordinating Center administers the tissue bank, coordinates the three oversight committees, maintains central access to clinical study data linked to the tissue bank, and provides statistical analysis.

Study Design

Study Type:

Observational

Official Title:

CSP #478 (FeAST-DNA), Genetic Tissue Banking in VA Clinical Research: A Cooperative Studies Program Demonstration Project

Study Start Date :

Jan 1, 2000

Outcome Measures

Primary Outcome Measures

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

This DNA Banking substudy piggybacks on VA Cooperative Studies Clinical Trials. All participants who are randomized to selected CSP clinical trials are eligible to participate in the Banking Initiative.

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Little Rock VAMC	Little Rock	Arkansas	United States	72205
2	VA Palo Alto Health Care System	Palo Alto	California	United States	94304
3	Louisville VAMC	Louisville	Kentucky	United States	40206
4	Durham VA Medical Center	Durham	North Carolina	United States	27705
5	VA Pittsburgh Health Care System	Pittsburgh	Pennsylvania	United States	15213
6	Salt Lake City VA Medical Center	Salt Lake City	Utah	United States	84148
7	White River Junction VAMC	White River Junction	Vermont	United States	05009
8	Madison VA Medical Center	Madison	Wisconsin	United States	53705

Sponsors and Collaborators

US Department of Veterans Affairs

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

Responsible Party:

, ,

ClinicalTrials.gov Identifier:

NCT00032578

Other Study ID Numbers:

478Fe

First Posted:

Mar 28, 2002

Last Update Posted:

Jan 21, 2009

Last Verified:

Jun 1, 2006

Study Results

No Results Posted as of Jan 21, 2009